| 2024 |
New small molecules for the Treatment of TNBC innovative Polypharmacological In Silico Approach |
Abstract in atti di convegno pubblicato in volume |
Vai |
| 2024 |
Scaffold-Hopping Strategies in Aurone Optimization: A Comprehensive Review of Synthetic Procedures and Biological Activities of Nitrogen and Sulfur Analogues |
Review essay (rassegna critica) |
Vai |
| 2024 |
Bioisosteric heterocyclic analogues of natural bioactive flavonoids by scaffold-hopping approaches: State-of-the-art and perspectives in medicinal chemistry |
Review essay (rassegna critica) |
Vai |
| 2024 |
A novel in silico approach for identifying multi-target JAK/STAT inhibitors as anticancer agents |
Articolo in rivista |
Vai |
| 2023 |
Design and Synthesis of Novel Thieno[3,2-c]quinoline Compounds with Antiproliferative Activity on RET-Dependent Medullary Thyroid Cancer Cells |
Articolo in rivista |
Vai |
| 2023 |
Synthesis of new antiproliferative 1,3,4-substituted-pyrrolo[3,2-c]quinoline derivatives, biological and in silico insights |
Articolo in rivista |
Vai |
| 2023 |
Indicaxanthin Induces Autophagy in Intestinal Epithelial Cancer Cells by Epigenetic Mechanisms Involving DNA Methylation |
Articolo in rivista |
Vai |
| 2023 |
In Silico Mixed Ligand/Structure-Based Design of New CDK-1/PARP-1 Dual Inhibitors as Anti-Breast Cancer Agents |
Articolo in rivista |
Vai |
| 2023 |
In silico lead optimization and synthesis of a new series of thieno[3,2-c]quinoline with antiproliferative activity on RET-dependent medullary thyroid cancer cells |
Abstract in atti di convegno pubblicato in volume |
Vai |
| 2023 |
In Silico Design of New Dual Inhibitors of SARS-CoV-2 MPRO through Ligand- and Structure-Based Methods |
Articolo in rivista |
Vai |
| 2022 |
Targeting SARS-CoV-2 Main Protease for Treatment of COVID-19: Covalent Inhibitors Structure-Activity Relationship Insights and Evolution Perspectives |
Articolo in rivista |
Vai |
| 2022 |
One pot-like regiospecific access to 1-aryl-1H-pyrazol-3(2H)-one derivatives and evaluation of the anticancer activity |
Articolo in rivista |
Vai |
| 2022 |
Phytochemical profile and antioxidant properties of the edible and non-edible portions of black sapote (Diospyros digyna Jacq.) |
Articolo in rivista |
Vai |
| 2022 |
Phytochemical Profile and Antioxidant, Antiproliferative, and Antimicrobial Properties of Rubus idaeus Seed Powder |
Articolo in rivista |
Vai |
| 2022 |
Antiproliferative Activity Predictor: un nuovo tool in silico per predire l’attività antiproliferativa nei confronti del pannello NCI60 |
Abstract in atti di convegno pubblicato in volume |
Vai |
| 2022 |
Antiproliferative Activity Predictor: A New Reliable In Silico Tool for Drug Response Prediction against NCI60 Panel |
Articolo in rivista |
Vai |
| 2021 |
Antiproliferative properties and g-quadruplex-binding of symmetrical naphtho[1,2-b:8,7-b’]dithiophene derivatives |
Articolo in rivista |
Vai |
| 2021 |
Bioactive triterpenes of protium heptaphyllum gum resin extract display cholesterol-lowering potential |
Articolo in rivista |
Vai |
| 2021 |
In silico identification of small molecules as new cdc25 inhibitors through the correlation between chemosensitivity and protein expression pattern |
Articolo in rivista |
Vai |
| 2021 |
Off-target-based design of selective hiv-1 protease inhibitors |
Articolo in rivista |
Vai |
| 2021 |
Identification of biological targets through the correlation between cell line chemosensitivity and protein expression pattern |
Review essay (rassegna critica) |
Vai |
| 2021 |
Quinoline anticancer agents active on DNA and DNA-interacting proteins: From classical to emerging therapeutic targets |
Articolo in rivista |
Vai |
| 2021 |
The dimer-monomer equilibrium of SARS-CoV-2 main protease is affected by small molecule inhibitors |
Articolo in rivista |
Vai |
| 2020 |
Vaccinium macrocarpon (Cranberry)-Based Dietary Supplements: Variation in Mass Uniformity, Proanthocyanidin Dosage and Anthocyanin Profile Demonstrates Quality Control Standard Needed |
Articolo in rivista |
Vai |
| 2020 |
DRUDIT: Web-based DRUgs DIscovery Tools to design small molecules as modulators of biological targets |
Articolo in rivista |
Vai |
| 2020 |
In Silico Insights into the SARS CoV-2 Main Protease Suggest NADH Endogenous Defences in the Control of the Pandemic Coronavirus Infection |
Articolo in rivista |
Vai |
| 2020 |
Quinoline-based molecules targeting c-Met, EGF, and VEGF receptors and the proteins involved in related carcinogenic pathways |
Articolo in rivista |
Vai |
| 2020 |
Identification of an LPS-induced chemo-attractive peptide from ciona robusta |
Articolo in rivista |
Vai |
| 2020 |
Synthesis, biological evaluation, and: In silico studies of novel chalcone: In pyrazoline-based 1,3,5-triazines as potential anticancer agents |
Articolo in rivista |
Vai |
| 2020 |
Design of antitumor drugs targeting c-kit receptor by a new mixed ligand-structure based method |
Articolo in rivista |
Vai |
| 2019 |
METHYLOMIC SIGNATURE AND MOLECULAR MODELLING TO BETTER UNDERSTAND AUTOPHAGY INDUCED BY PHYTOCHEMICAL IN CACO-2
CELLS |
Abstract in atti di convegno pubblicato in volume |
Vai |
| 2019 |
Melatonin reduces inflammatory response in human intestinal epithelial cells stimulated by interleukin-1β |
Articolo in rivista |
Vai |
| 2018 |
Design, synthesis, and biological evaluation of a new class of benzo[b]furan derivatives as antiproliferative agents, with in silico predicted antitubulin activity |
Articolo in rivista |
Vai |
| 2018 |
Protective effects of melatonin in inflamed intestinal epithelium are associated with reduced NF-κB activation and changes in DNA methylation status |
Abstract in atti di convegno pubblicato in volume |
Vai |
| 2018 |
New insights into the mechanism of action of pyrazolo[1,2-a]benzo[1,2,3,4]tetrazin-3-one derivatives endowed with anticancer potential |
Articolo in rivista |
Vai |
| 2018 |
The interaction of Schiff Base complexes of nickel(II) and zinc(II) with duplex and G-quadruplex DNA |
Articolo in rivista |
Vai |
| 2017 |
Kinase Inhibitors in Multitargeted Cancer Therapy |
Articolo in rivista |
Vai |
| 2017 |
Melatonin Inhibits Inflammatory Response of Intestinal Epithelial Cells |
Abstract in atti di convegno pubblicato in volume |
Vai |
| 2017 |
Curcumin-like compounds designed to modify amyloid beta peptide aggregation patterns |
Articolo in rivista |
Vai |
| 2016 |
Drugs Polypharmacology by In Silico Methods: New Opportunities in Drug Discovery |
Articolo in rivista |
Vai |
| 2016 |
G-quadruplex vs. duplex-DNA binding of nickel(II) and zinc(II) Schiff base complexes |
Articolo in rivista |
Vai |
| 2016 |
The Repurposing of Old Drugs or Unsuccessful Lead Compounds by in Silico Approaches: New Advances and Perspectives |
Articolo in rivista |
Vai |
| 2016 |
Heterocyclic Scaffolds for the Treatment of Alzheimer's Disease |
Articolo in rivista |
Vai |
| 2015 |
Theoretical Determination of the pK a Values of Betalamic Acid Related to the Free Radical Scavenger Capacity: Comparison Between Empirical and Quantum Chemical Methods |
Articolo in rivista |
Vai |
| 2015 |
Evaluation of matrix effect on the GC/MS response of eighteen pesticides by multivariate approach |
Proceedings |
Vai |
| 2015 |
Synthesis, antiproliferative activity, and in silico insights of new 3-benzoylamino-benzo[ b ]thiophene derivatives |
Articolo in rivista |
Vai |
| 2015 |
Selective in vitro antileukemic activity (HL-60, K-562, MOLT-4, SR) of new chloro-propyl-pyrazolo[1,2-a]benzo[1,2,5]triazepinones |
Poster pubblicato in volume |
Vai |
| 2015 |
Ni(II) and Zn(II) Schiff Base complexes: B-DNA vs G4-DNA binding |
Abstract in atti di convegno pubblicato in volume |
Vai |
| 2015 |
Zinc complexes as fluorescent chemosensors for nucleic acids: New perspectives for a "boring" element |
Articolo in rivista |
Vai |
| 2014 |
G4-DNA vs. B-DNA binding of Schiff base transition metal complexes |
Proceedings |
Vai |
| 2014 |
Selective G-Quadruplex Stabilizers: Schiff-base Metal Complexes with Anticancer Activity |
Articolo in rivista |
Vai |
| 2014 |
New benzothieno[3,2-d]-1,2,3-triazines with antiproliferative activity: Synthesis, spectroscopic studies, and biological activity |
Articolo in rivista |
Vai |
| 2014 |
1,2,3-Triazole in Heterocyclic Compounds, Endowed with Biological Activity, through 1,3-Dipolar Cycloadditions |
Articolo in rivista |
Vai |
| 2014 |
In silico, spectroscopic, and biological insights on annelated pyrrolo[3,2-e]pyrimidines with antiproliferative activity |
Articolo in rivista |
Vai |
| 2014 |
Nickel(II), copper(II) and zinc(II) metallo-intercalators: structural details of the DNA-binding by a combined experimental and computational investigation |
Articolo in rivista |
Vai |
| 2014 |
Molecular dynamics, dynamic site mapping, and highthroughput virtual screening on leptin and the Ob receptor as anti-obesity target |
Articolo in rivista |
Vai |
| 2014 |
Multivariate analysis in the identification of biological targets for designed molecular structures: The BIOTA protocol |
Articolo in rivista |
Vai |
| 2014 |
NiII, and ZnII Schiff Base Complexes: Telomeric G-quadruplex Stabilizers |
Proceedings |
Vai |
| 2014 |
A human CCT5 gene mutation causing distal neuropathy impairs hexadecamer assembly in an archaeal model |
Articolo in rivista |
Vai |
| 2014 |
Leptin and the ob-receptor as anti-obesity target: recent in silico advances in the comprehension of the protein-protein interaction and rational drug design of anti-obesity lead compounds |
Articolo in rivista |
Vai |
| 2014 |
The Interaction of Small Molecules with Biomolecules |
Proceedings |
Vai |
| 2014 |
The role of side chains in Substituted Pyrrole derivatives towards antiproliferative activity |
Proceedings |
Vai |
| 2014 |
Does ligand symmetry play a role in the stabilization of DNA g-quadruplex host-guest complexes? |
Articolo in rivista |
Vai |
| 2014 |
DA-Phen, a new dopamine aminoacid conjugate: in vivo testing and molecular modeling as dopaminergic modulator |
Proceedings |
Vai |
| 2014 |
Double chained naphthalenes as G4 binders |
Proceedings |
Vai |
| 2014 |
DNA-Binding of NiII, CuII and ZnII Complexes of Salen Derivatives |
Proceedings |
Vai |
| 2013 |
An Unexpected Dimroth Rearrangement Leading to Annelated Thieno[3,2-d][1,2,3]triazolo[1,5-a]pyrimidines with Potent Antitumor Activity |
Articolo in rivista |
Vai |
| 2013 |
Synthesis and biological activities of a new class of heat shock protein 90 inhibitors, designed by energy-based pharmacophore virtual screening |
Articolo in rivista |
Vai |
| 2013 |
The influence of substitution in the quinoxaline nucleus on 1,3-dipolar cycloaddition reactions |
Articolo in rivista |
Vai |
| 2013 |
New annelated thieno[2,3-e][1,2,3]triazolo[1,5-a]pyrimidines, with potent anticancer activity, designed through VLAK protocol |
Articolo in rivista |
Vai |
| 2013 |
Hsp60, a novel target for antitumor therapy: Structure-function features and prospective drugs design |
Articolo in rivista |
Vai |
| 2013 |
DNA-binding of nickel(II), copper(II) and zinc(II) complexes: structure-affinity relationships |
Articolo in rivista |
Vai |
| 2013 |
Verso l’ottimizzazione dell’attività antiproliferativa di derivati pirroloisochinolinici |
Proceedings |
Vai |
| 2013 |
A3 adenosine receptor: Homology modeling and 3D-QSAR studies |
Articolo in rivista |
Vai |
| 2013 |
SELECTIVE G-QUADRUPLEX STABILIZERS: SALPHEN-LIKE COMPLEXES WITH ANTIPROLIFERATIVE ACTIVITY |
Proceedings |
Vai |
| 2013 |
Theoretical Determination Of The pKas Of Betalamic Acid Related To The Free-Radical Scavenger Capacity: Comparison Between Semi-Empirical And Ab Initio Methods |
Proceedings |
Vai |
| 2013 |
Design and synthesis of high affinity compounds for the Hsp60 expression
control in carcinogenic processes |
Proceedings |
Vai |
| 2013 |
Exploring the anticancer potential of pyrazolo[1,2-a]benzo[1,2,3,4]tetrazin-3-one derivatives: The effect on apoptosis induction, cell cycle and proliferation |
Articolo in rivista |
Vai |
| 2013 |
SYNTHESIS AND EVALUATION OF CURCUMIN ANALOGUES AS NEURO-PROTECTIVE AGENTS FOR THE ALZHEIMER'S DISEASE |
Proceedings |
Vai |
| 2012 |
DERIVATI TIENO[3,2-d]-1,2,3-TRIAZIN-4(3H)ONI ANELLATI:UNA NUOVA CLASSE DI INIBITORI DI AURORA CHINASI A |
Proceedings |
Vai |
| 2012 |
Synthesis, characterization and DNA binding studies of potential G4 stabilizer metal complexes |
Proceedings |
Vai |
| 2012 |
IN THE SEARCH OF LEPTIN AGONISTS AS ANTI-OBESITY DRUGS:
PROTEIN/PROTEIN DOCKING, MOLECULAR DYNAMICS, AND
VIRTUAL SCREENING |
Proceedings |
Vai |
| 2012 |
Molecular Modelling on Leptin and the Ob Receptor as anti-obesity target |
Proceedings |
Vai |
| 2012 |
In vitro and in silico studies of polycondensed diazine systems as
anti-parasitic agents |
Articolo in rivista |
Vai |
| 2012 |
Molecular Dynamics studies on Mdm2 complexes: an analysis of the inhibitor
influence |
Articolo in rivista |
Vai |
| 2012 |
Pharmacophore modelling as useful tool in the lead compounds identification
and optimization |
Proceedings |
Vai |
| 2012 |
Antiproliferative activity of Pyrrolo[3,2-c]quinoline derivatives |
Proceedings |
Vai |
| 2012 |
Receptor-guided 3D-QSAR approach for the discovery
of c-kit tyrosine kinase inhibitors |
Articolo in rivista |
Vai |
| 2012 |
Lead optimization through VLAK protocol: New annelated pyrrolo-pyrimidine derivatives as antitumor agents |
Articolo in rivista |
Vai |
| 2012 |
1,2-Dihydropyrazole[1,2-a]benzo[1,2,4]triazine-3-one: deaza analogue tricyclic scaffold with valuable antiproliferative activity |
Proceedings |
Vai |
| 2012 |
Studio del ruolo delle mutazioni “gatekeeper” V654A e T670I di c-kit kinase nell’interazione con inibitori attraverso un approccio misto Dinamica Molecolare/Docking |
Proceedings |
Vai |
| 2012 |
NOVEL ANTAGONISTS FOR AN Hsp60-BASED ANTICANCER
CHAPERONOTHERAPY |
Proceedings |
Vai |
| 2011 |
Nuovi inibitori di Aurora chinasi A come target biologico coinvolto nei processi carcinogenici |
Proceedings |
Vai |
| 2011 |
Synthesis and antiproliferative activity of Naphtalenyl substituted 1,2-dihydropyrazol-5-one and related fused tetrazine |
Proceedings |
Vai |
| 2011 |
Study of the role of “gatekeeper” mutations V654A
and T670I of c-kit kinase in the interaction with
inhibitors by means mixed molecular
dynamics/docking approach |
Articolo in rivista |
Vai |
| 2011 |
In vitro and in silico studies of polycondensed diazine systems as anti-infective agents |
Proceedings |
Vai |
| 2011 |
A3 Adenosine Receptor: homology modeling and
3D-QSAR studies |
Proceedings |
Vai |
| 2011 |
STUDIO DELL'INTERAZIONE DI DNA-NATIVO CON Zn(3-ACETIL-1-(2-NITROFENIL)PENTAN-1,4-DIONATO)2 |
Proceedings |
Vai |
| 2011 |
Virtual lock-and-key approach: The in silico revival of Fischer model by means
of molecular descriptors |
Articolo in rivista |
Vai |
| 2010 |
Inside c-kit tyrosine kinase: molecular modeling and
QSAR in the search of new inhibitors |
Proceedings |
Vai |
| 2010 |
Design, synthesis, and biological evaluation of pyridothienotriazolopyrimidine derivatives as new HSP90 inhibitors |
Proceedings |
Vai |
| 2010 |
TECNICHE DI MODELLISTICA MOLECOLARE NELLA PROGETTAZIONE DI INIBITORI DELL'ATTIVITÀ TRASCRIZIONALE DI HIF-1 |
Proceedings |
Vai |
| 2010 |
Molecular Modeling Approaches in the Discovery of New Drugs for Anti-Cancer Therapy: The Investigation of p53-MDM2 Interaction and its Inhibition by Small Molecules |
Articolo in rivista |
Vai |
| 2010 |
The discovery of new inhibitors of HIF-1 transcriptional activity by virtual screening |
Proceedings |
Vai |
| 2010 |
3D-QSAR Pharmacophore Modeling and in Silico Screening of new Bcl-xl Inhibitors |
Articolo in rivista |
Vai |
| 2010 |
IKK-beta inhibitors: An analysis of drug–receptor interaction by using Molecular Docking and Pharmacophore 3D-QSAR approaches |
Articolo in rivista |
Vai |
| 2010 |
Design of new DNA-interactive agents
by molecular docking and QSPR approach |
Articolo in rivista |
Vai |
| 2010 |
THE PURPOSING OF NEW COMPOUNDS OR THE RE-PURPOSING OF OLD DRUGS BY MEANS OF MULTIVARIATE ANATYSIS ON
MOLECULAR DESCRIPTORS |
Proceedings |
Vai |
| 2010 |
Study of Reactivity in the 1,3-Dipolar Cycloaddition Reactions Leading to New Triazolopyrrolopyrazine Ring Systems |
Articolo in rivista |
Vai |
| 2010 |
THE DISCOVERY OF NEW HIF-1 INHIBITORS THROUGH
MOLECULAR MODELING STUDIES |
Proceedings |
Vai |
| 2009 |
Molecular Modeling and Dynamics of the transcriptionfactor NF-kB complexed with IkB |
Proceedings |
Vai |
| 2009 |
Combined use of PCA and QSAR/QSPR to predict the drugs mechanism of action. An application to the NCI ACAM Database |
Articolo in rivista |
Vai |
| 2009 |
Targeted synthesis of pyrrolo tricycles for selective biomolecules overexpressed in cancer cells |
Proceedings |
Vai |
| 2009 |
PROGETTAZIONE, SINTESI E VALUTAZIONE BIOLOGICA DI NUOVI INIBITORI DI HSP90 |
Proceedings |
Vai |
| 2009 |
In-silico screening of new potential Bcl-2/Bcl-xl inhibitors as apoptosis modulators |
Articolo in rivista |
Vai |
| 2009 |
A QSAR study investigating the potential anti-HIV-1 effect of some Acyclovir and Ganciclovir analogs |
Articolo in rivista |
Vai |
| 2009 |
Inside the Hsp90 inhibitors binding mode through induced fit docking |
Articolo in rivista |
Vai |
| 2009 |
Virtual lock and key approach: the revival of Fischer model |
Proceedings |
Vai |
| 2009 |
Computational methodologies in the discovery of inhibitors of HIV-1 |
Proceedings |
Vai |
| 2009 |
Apoptotic induction on HeLa tumor cell
line. A comparison of activity between
pyrazolo[1,2-a]benzo[1,2,3,4]tetrazinone
derivatives and their synthetic precursors |
Proceedings |
Vai |
| 2009 |
The Role of 1,3-Dipolar Cycloaddition Reactions in the Design and Synthesis of Complex Heterocyclic Scaffolds with Anti-tumor/Anti-infective Activity |
Proceedings |
Vai |
| 2009 |
SCREENING APOPTOTICI SU NUOVI DERIVATI PIRAZOLO[1,2-A]BENZO[1,2,3,4]TETRAZINONI |
Proceedings |
Vai |
| 2009 |
Studi di dinamica molecolare su Mdm2 legata a due differenti inibitori |
Proceedings |
Vai |
| 2009 |
The influence of acidic pH environment in regulating the activity of novel HIF-1 inhibitors |
Proceedings |
Vai |
| 2009 |
Reactivity of asymmetric benzo-condensed diazines with nitrilimine dipoles in the 1,3-dipolar cycloaddition reactions |
Articolo in rivista |
Vai |
| 2009 |
Principal component analysis on molecular descriptors as an alternative point of view in the search of new Hsp90 inhibitors |
Articolo in rivista |
Vai |
| 2008 |
PCA and QSAR/QSPR used in combination to predict the drugs mechanism of action. An application to the NCI ACAM Database |
Proceedings |
Vai |
| 2008 |
Sintesi di Nuovi Derivati del Sistema Triciclico Pirazolo[3,4-d][1,2,3]triazolo[1,5-a]pirimidinico DNA interattivi |
Proceedings |
Vai |
| 2008 |
Bis-1,2,4-triazolo[4,3-a:3',4'-c]quinoxalines of pharmaceutical interest from 1,3-dipolar cycloaddition |
Articolo in rivista |
Vai |
| 2008 |
Pyrazolo[3,4-d][1,2,3]triazolo[1,5-a]pyrimidine: a new ring system through Dimroth rearrangement |
Articolo in rivista |
Vai |
| 2008 |
Pharmacophore modeling e screening in silico di nuovi inibitori della proteina antiapoptotica Bcl-xl |
Proceedings |
Vai |
| 2008 |
BINDING MODES OF HSP90 INHIBITORS INVESTIGATED THROUGH INDUCED FIT DOCKING: IMPORTANCE OF ACTIVE SITE FLEXIBILITY |
Proceedings |
Vai |
| 2008 |
Intercalation of daunomycin into stacked DNA base pairs. DFT study of an anticancer drug |
Articolo in rivista |
Vai |
| 2008 |
La chemiometria ed il molecular modeling in ausilio alla scoperta ed all’ottimizzazione di lead compounds |
Proceedings |
Vai |
| 2008 |
MOLECULAR DYNAMICS AND DOCKING IN THE STUDY OF NEW INHIBITORS OF MDM2-p53 INTERACTION |
Proceedings |
Vai |
| 2008 |
1,3-Dipolar cycloadditions in the synthesis of annelated diazines: design of new scaffolds for anticancer and antimicrobial agents |
Proceedings |
Vai |
| 2008 |
Study on the mechanism of action of antitumor photochemotherapic agents by means of docking and QSPR analysis |
Proceedings |
Vai |
| 2008 |
Identificazione e sintesi di nuovi potenziali inibitori di Heat Shock Protein 90 |
Proceedings |
Vai |
| 2008 |
Investigation of flap motions in wild type and M46I/G51D Mutant HIV-1 Protease by molecular dynamics studies |
Proceedings |
Vai |
| 2008 |
DOCKING AND MULTIVARIATE METHODS TO EXPLORE HIV-1 DRUG-RESISTANCE: A COMPARATIVE ANALYSIS |
Articolo in rivista |
Vai |
| 2008 |
LOOKING FOR NEW HSP-90 INHIBITORS THROUGH A MOLECULAR DOCKING/PHARMACOPHORE APPROACH |
Proceedings |
Vai |
| 2008 |
New imidazo[1,2-c]pyrrolo[3,2-e]pyrimidinone derivatives as potential DNA-binders |
Proceedings |
Vai |
| 2008 |
Principal Component Analysis on molecular descriptors as alternative point of view in the search of new Hsp90 inhibitors |
Proceedings |
Vai |
| 2008 |
Nuovi derivati 3,5-diaril-4,5-diidropirazolici come inibitori di HSP90 |
Proceedings |
Vai |
| 2008 |
Design and Synthesis of 4-Substituted Indolo[3,2-e][1,2,3]triazolo[1,5-a]pyrimidine Derivatives with Antitumor Activity |
Articolo in rivista |
Vai |
| 2007 |
Benzothieno-triazolo-pyrimidine: a new class of potential DNA-binders |
Proceedings |
Vai |
| 2007 |
Sintesi di derivati tetraidrobis-triazolochinossalinici e di nuovi sistemi triazolopirrolopirazinici di interesse biologico mediante cicloaddizioni 1,3-dipolari |
Proceedings |
Vai |
| 2007 |
DNA minor groove binders: an overview on molecular modeling and QSAR approaches |
Articolo in rivista |
Vai |
| 2007 |
Reattività di diazine benzocondensate asimmetriche nelle reazioni di cicloaddizione 1,3-dipolare con dipoli nitriliminici |
Proceedings |
Vai |
| 2007 |
Molecular dynamics studies on HIV-1 protease: a comparison of the flap motions between wild type protease and the M46I/G51D double mutant |
Articolo in rivista |
Vai |
| 2007 |
Protocollo chemiometrico per la predizione del meccanismo di azione di derivati a potenziale attività antitumorale |
Proceedings |
Vai |
| 2007 |
Docking and synthesis of pyrrolopyrimidodiazepinone derivatives (PPDs) and their precursors: new scaffolds for DNA-interacting agents |
Articolo in rivista |
Vai |
| 2007 |
Studi spettroscopici su complessi indolotriazolopirimidina-DNA nativo. |
Proceedings |
Vai |
| 2007 |
Molecular Docking approach on the Topoisomerase I inhibitors series included in the NCI anti-cancer agents mechanism database |
Articolo in rivista |
Vai |
| 2007 |
Bcl-2 come target di farmaci antitumorali modulatori dell'apoptosi |
Proceedings |
Vai |
| 2007 |
Potenziali agenti DNA-interattivi: Benzotieno[2,3-e][1,2,3]triazolo[1,5-a]pirimidine |
Proceedings |
Vai |
| 2007 |
New triazolo-pyrrolopyrazine systems by 1,3-dipolar cycloaddition |
Proceedings |
Vai |
| 2007 |
ISOINDOLO[2,1-C]BENZO[1,2,4]TRIAZINES: A NEW RING SYSTEM WITH ANTIPROLIFERATIVE ACTIVITY |
Articolo in rivista |
Vai |
| 2007 |
Molecular modelling and QSAR in the discovery of HIV-1 integrase inhibitors |
Articolo in rivista |
Vai |
| 2007 |
Pirazolo[3,4-d][1,2,3]triazolo[1,5-a]pirimidina: accesso sintetico tramite cicloaddizioni 1,3-dipolari e riarrangiamento di Dimroth |
Proceedings |
Vai |
| 2006 |
A synthetic approach to new polycyclic ring system of biologial interest through domino reaction: indolo[2,3-e][1,2,3]triazolo[1,5-a]pyrimidine |
Articolo in rivista |
Vai |
| 2006 |
Sintesi di derivati triazolo-chinossalinici e triazolo-pirrolopirazinici di interesse farmaceutico mediante cicloaddizioni 1,3-dipolari |
Proceedings |
Vai |
| 2006 |
NCI Anti-cancer agent mechanism database. An analysis by the combined use of molecular docking and QSPR |
Proceedings |
Vai |
| 2006 |
A convenient synthesis of cycloadduct bis-1,2,4-triazolo[4,3-a:3’,4’-c]quinoxalines by 1,3-dipolar cycloaddition |
Proceedings |
Vai |
| 2006 |
A Multivariate Analysis of HIV-1 Protease Inhibitors and Resistance Induced by Mutation |
Articolo in rivista |
Vai |
| 2006 |
1,3-Dipolar cycloaddition in the synthesis of a new potential DNA-intercalating agent: indolo[3,2-e]pyrrolo[1,2-c]triazolo[1,5-a]pyrimidine |
Proceedings |
Vai |
| 2006 |
A multivariate analysis on HIV-1 protease inhibitors and resistance induced by mutation |
Proceedings |
Vai |
| 2006 |
Bis-1,2,4-triazolo[4,3-a:3’,4’-c]quinoxalines of pharmaceutical interest from 1,3-dipolar cycloaddition |
Proceedings |
Vai |
| 2006 |
MADoSPRO: a new Approach to Molecular Modelling Studies on a Series of DNA Minor Groove Binders |
Articolo in rivista |
Vai |
| 2006 |
Molecular modelling studies on new series of DNA-interactive annelated pyrrolo-pyrimidines |
Proceedings |
Vai |
| 2006 |
Molecular Docking and QSPR approach on NCI Anti-Cancer Agents Mechanism Database Topoisomerase I inhibitors |
Proceedings |
Vai |
| 2005 |
A new Approach to Molecular Modelling Studies on a Series of DNA Minor Groove Binders |
Articolo in rivista |
Vai |
| 2005 |
1-Methyl-3H-pyrazolo[1,2-a]benzo[1,2,3,4]tetrazin-3-ones. Design, Synthesis, and Biological Activity of New Antitumor Agents |
Articolo in rivista |
Vai |
| 2005 |
New Tricyclic System of Biological Interest Thieno[3,2-e][1,2,3]triazolo[1,5-a]pyrimidine Trough Domino Reactions of 2-Azidothiophene. |
Proceedings |
Vai |
| 2005 |
SYNTHESIS AND PHOTOCHEMIOTHERAPEUTIC ACTIVITY OF THIOPYRANO[2,3-E]INDOL-2-ONES |
Articolo in rivista |
Vai |
| 2005 |
SYNTHESIS OF 3,5-BIS(3'-INDOLYL)PYRAZOLES, ANALOGUES OF NORTOPSENTIN |
Proceedings |
Vai |
| 2005 |
In House Methodology to Assign the Mechanism of Action of New Annelated Triazolopyrimidine Derivatives with Anticancer Activity |
Proceedings |
Vai |
| 2005 |
Isoindolo[1,2-a]quinoxaline derivatives with potent antitumor activity. |
Proceedings |
Vai |
| 2005 |
A General Treatment of Solubility. 3. Principal Component Analysis (PCA) of the Solubilities of Diverse Solutes in Diverse Solvents |
Altro |
Vai |
| 2005 |
2,5-bis(3'-Indolyl)thiophenes, Analogues of Marine Alkaloid Nortopsentin. |
Proceedings |
Vai |
| 2005 |
Analisi Multivariata e Docking nello Studio degli Inibitori di HIV-1 Integrasi |
Proceedings |
Vai |
| 2005 |
HIV-1 Protease Inhibitors and Resistance Induced by Mutation. Correlation between Multivariate Analysis and Molecular Docking. |
Proceedings |
Vai |
| 2005 |
2-OXO-[1,4]OXAZINO[3,2-E]INDOLE: A NEW RING SYSTEM WITH POTENTIAL PHOTOBIOLOGICAL PROPERTIES |
Proceedings |
Vai |
| 2005 |
Synthesis and Antiproliferative Activity of [1,2,3,5]tetrazino[5,4-a]indoles, a New Class of Azolo-tetrazinones |
Articolo in rivista |
Vai |
| 2005 |
Annelated Pyrrolo-pyrimidines from Amino-cyanopyrroles and BMMAs as Leads for New DNA-interactive Ring Systems |
Articolo in rivista |
Vai |
| 2004 |
Sintesi ed Attivita’ Fotobiologica di Tiopirano[2,3-c]indol-2-oni |
Proceedings |
Vai |
| 2004 |
Sintesi di Nuovi Derivati 2,5-bis(3’Indolil)tiofeni, Analoghi dell’Alcaloide Marino Nortopsentina. |
Proceedings |
Vai |
| 2004 |
European School of Medicinal Chemistry (Advanced Course of Medicinal Chemistry and National Seminar "E.Duranti" for PhD students) |
Altro |
Vai |
| 2004 |
Studi di Docking su Isomeri della Distamicina e della Netropsina |
Proceedings |
Vai |
| 2004 |
Synthesis and Antiproliferative Activity of [1,2,4]triazino[4,3-a]indoles |
Articolo in rivista |
Vai |
| 2004 |
“QSPR, Sintesi ed Attività Biologica di Nuovi Derivati del Sistema Tetraciclico Indolo[3,2-e][1,2,3]triazolo[1,5-a]pirimidinico.” |
Proceedings |
Vai |
| 2004 |
Pirrolo[3,4-h]chinolinoni: Potenziali Agenti Fotochemioterapici |
Proceedings |
Vai |
| 2004 |
Studi di Modellistica Molecolare e Sintesi di Sistemi Indolotriazolopirimidinici |
Proceedings |
Vai |
| 2004 |
Studi di Molecular Modelling su Derivati del Nuovo Sistema Eterociclico DNA-interattivo Isoindolo[2,1-c]benzo[1,2,4]triazina |
Proceedings |
Vai |
| 2004 |
Principal Component Analysis (PCA) of the Solubility |
Proceedings |
Vai |
| 2004 |
Molecular Modelling Studies on New Series of DNA-Interactive annelated Pyrrolo-pyrimidines |
Proceedings |
Vai |
| 2004 |
Sintesi di Oligopeptidi Pirrolici Isomeri della Distamicina e della Netropsina |
Proceedings |
Vai |
| 2004 |
Docking of indolo- and pyrrolo-pyrimidines to DNA. New DNA-interactive polycycles from amino-indoles/pyrroles and BMMA. |
Articolo in rivista |
Vai |
| 2004 |
A multivariate analysis on non-nucleoside HIV-1 reverse transcriptase inhibitors and resistance induced by mutation |
Articolo in rivista |
Vai |
