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STELLA MARIA CASCIOFERRO

Curriculum and Research

CASCIOFERRO STELLA MARIA

STELLA MARIA CASCIOFERRO

 (CHEM-07/A)

Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche

Contacts

+3909123896820

stellamaria.cascioferro@unipa.it

Curriculum not available

Subjects

Academic Year Subject identification code Subject name ECTS Course of study
2024/2025 01205 ANALISI DEI FARMACI 10 CHIMICA E TECNOLOGIA FARMACEUTICHE
2024/2025 01215 ANALISI DEI MEDICINALI 2 10 FARMACIA

Publications

Date Title Type Record
2024 Exploring the therapeutic potential of a novel series of imidazothiadiazoles targeting focal adhesion kinase (FAK) for pancreatic cancer treatment: synthesis, mechanistic insights and promising antitumor and safety profile Articolo in rivista Go to
2024 Exploring the therapeutic potential of focal adhesion kinase inhibition in overcoming chemoresistance in pancreatic ductal adenocarcinoma Review essay (rassegna critica) Go to
2024 Triazole derivatives inhibit the VOR complex-mediated nuclear transport of extracellular particles: Potential application in cancer and HIV-1 infection Articolo in rivista Go to
2024 Novel [1,3,4]Thiadiazole[3,2-a]pyrimidin-5-ones as Promising Biofilm Dispersal Agents against Relevant Gram-Positive and Gram-Negative Pathogens Articolo in rivista Go to
2023 Recent Developments in the Inhibition of Bacterial Adhesion as Promising Anti-Virulence Strategy Articolo in rivista Go to
2023 Nortopsentins as Leads from Marine Organisms for Anticancer and Anti-Inflammatory Agent Development Review essay (rassegna critica) Go to
2023 Development of a new indole derivative dry powder for inhalation for the treatment of biofilm-associated lung infections Articolo in rivista Go to
2023 Multi or Single-Kinase Inhibitors to Counteract Drug Resistance in Cancer: What is New? Articolo in rivista Go to
2023 Structural Manipulations of Marine Natural Products Inspire a New Library of 3-Amino-1,2,4-Triazine PDK Inhibitors Endowed with Antitumor Activity in Pancreatic Ductal Adenocarcinoma Articolo in rivista Go to
2023 Discovery of the 3-Amino-1,2,4-triazine-Based Library as Selective PDK1 Inhibitors with Therapeutic Potential in Highly Aggressive Pancreatic Ductal Adenocarcinoma Articolo in rivista Go to
2023 A Combination of Polymethoxyflavones from Citrus sinensis and Prenylflavonoids from Humulus lupulus Counteracts IL-1β-Induced Differentiated Caco-2 Cells Dysfunction via a Modulation of NF-κB/Nrf2 Activation Articolo in rivista Go to
2023 1,2,4-Amino-triazine derivatives as pyruvate dehydrogenase kinase inhibitors: Synthesis and pharmacological evaluation Articolo in rivista Go to
2023 1,3,4-Oxadiazole and 1,3,4-Thiadiazole Nortopsentin Derivatives against Pancreatic Ductal Adenocarcinoma: Synthesis, Cytotoxic Activity, and Inhibition of CDK1 Articolo in rivista Go to
2022 Eight-Membered Rings With Two Heteroatoms 1,2 Capitolo o Saggio Go to
2022 Eight-Membered Rings With Two Heteroatoms 1,3 Capitolo o Saggio Go to
2022 Biofilm Formation as Valuable Target to Fight against Severe Chronic Infections Articolo in rivista Go to
2022 Eight-Membered Rings With Two Heteroatoms 1,5 Capitolo o Saggio Go to
2022 A New Oxadiazole-Based Topsentin Derivative Modulates Cyclin-Dependent Kinase 1 Expression and Exerts Cytotoxic Effects on Pancreatic Cancer Cells Articolo in rivista Go to
2022 Metabolomics-assisted discovery of a new anticancer GLS-1 inhibitor chemotype from a nortopsentin-inspired library: From phenotype screening to target identification Articolo in rivista Go to
2022 Eight-membered heterocycles with two heteroatoms in a 1,3-relationship of interest in medicinal chemistry Capitolo o Saggio Go to
2021 Itraconazole inhibits nuclear delivery of extracellular vesicle cargo by disrupting the entry of late endosomes into the nucleoplasmic reticulum Articolo in rivista Go to
2021 Nobiletin and Xanthohumol Sensitize Colorectal Cancer Stem Cells to Standard Chemotherapy Articolo in rivista Go to
2021 Dynamic-shared pharmacophore approach as tool to design new allosteric PRC2 inhibitors, targeting EED binding pocket Articolo in rivista Go to
2021 Eight-membered heterocycles with two heteroatoms in a 1,2-relationship of interest in medicinal chemistry Capitolo o Saggio Go to
2021 Therapeutic strategies to counteract antibiotic resistance in MRSA biofilm-associated infections Review essay (rassegna critica) Go to
2021 CHK1 inhibitor sensitizes resistant colorectal cancer stem cells to nortopsentin Articolo in rivista Go to
2021 Overcome Chemoresistance: Biophysical and Structural Analysis of Synthetic FHIT-Derived Peptides Articolo in rivista Go to
2021 Novel strategies in the war against antibiotic resistance Articolo in rivista Go to
2021 SF3B1 modulators affect key genes in metastasis and drug influx: a new approach to fight pancreatic cancer chemoresistance Articolo in rivista Go to
2021 1,2,4-Oxadiazole Topsentin Analogs with Antiproliferative Activity against Pancreatic Cancer Cells, Targeting GSK3β Kinase Articolo in rivista Go to
2021 1,2,4-Oxadiazole topsentin analogs as staphylococcal biofilm inhibitors targeting the bacterial transpeptidase sortase A Articolo in rivista Go to
2021 Thiazole Analogues of the Marine Alkaloid Nortopsentin as Inhibitors of Bacterial Biofilm Formation Articolo in rivista Go to
2020 Inhibitors of antibiotic resistance mechanisms: clinical applications and future perspectives Articolo in rivista Go to
2020 Imidazo[2,1-b] [1,3,4]thiadiazoles with antiproliferative activity against primary and gemcitabine-resistant pancreatic cancer cells Articolo in rivista Go to
2020 3-(6-Phenylimidazo [2,1-b][1,3,4]thiadiazol-2-yl)-1HIndole derivatives as new anticancer agents in the treatment of pancreatic ductal adenocarcinoma Articolo in rivista Go to
2020 Eight-membered heterocycles with two heteroatoms in a 1,5-relationship of interest in medicinal chemistry Capitolo o Saggio Go to
2020 Thiazoles, Their Benzofused Systems, and Thiazolidinone Derivatives: Versatile and Promising Tools to Combat Antibiotic Resistance Articolo in rivista Go to
2020 Bioactive Polyphenols from Pomegranate Juice Reduce 5-Fluorouracil-Induced Intestinal Mucositis in Intestinal Epithelial Cells Articolo in rivista Go to
2020 Citrus sinensis and Vitis vinifera Protect Cardiomyocytes from Doxorubicin-Induced Oxidative Stress: Evaluation of Onconutraceutical Potential of Vegetable Smoothies Articolo in rivista Go to
2020 New Imidazo[2,1-b][1,3,4]Thiadiazole Derivatives Inhibit FAK Phosphorylation and Potentiate the Antiproliferative Effects of Gemcitabine Through Modulation of the Human Equilibrative Nucleoside Transporter-1 in Peritoneal Mesothelioma Articolo in rivista Go to
2020 Open Sesame? : Biomarker Status of the Human Equilibrative Nucleoside Transporter-1 and Molecular Mechanisms Influencing its Expression and Activity in the Uptake and Cytotoxicity of Gemcitabine in Pancreatic Cancer Articolo in rivista Go to
2020 Impact of hypoxia on chemoresistance of mesothelioma mediated by the proton-coupled folate transporter, and preclinical activity of new anti-LDH-A compounds Articolo in rivista Go to
2019 2,6-Disubstituted imidazo[2,1-b][1,3,4]thiadiazole derivatives as potent staphylococcal biofilm inhibitors Articolo in rivista Go to
2019 A Synthetic Derivative of Antimicrobial Peptide Holothuroidin 2 from Mediterranean Sea Cucumber (Holothuria tubulosa) in the Control of Listeria monocytogenes Articolo in rivista Go to
2019 Biological evaluation of new 1,2,4-oxadiazole topsentin analogs as anticancer agents Abstract in atti di convegno pubblicato in volume Go to
2019 Synthesis and photocytotoxic activity of [1,2,3]triazolo[4,5-h][1,6]naphthyridines and [1,3]oxazolo[5,4-h][1,6]naphthyridines Articolo in rivista Go to
2019 Synthesis of novel 1,2,4-oxadiazole topsentin analogs with antitumor activity Contributo in atti di convegno pubblicato in volume Go to
2019 β -Lactoglobulin Heptapeptide Reduces Oxidative Stress in Intestinal Epithelial Cells and Angiotensin II-Induced Vasoconstriction on Mouse Mesenteric Arteries by Induction of Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) Translocation Articolo in rivista Go to
2019 Quality, functional and sensory evaluation of pasta fortified with extracts from Opuntia ficus-indica cladodes Articolo in rivista Go to
2019 Synthetic small molecules as anti-biofilm agents in the struggle against antibiotic resistance Articolo in rivista Go to
2019 Pharmacogenetics of treatments for pancreatic cancer Articolo in rivista Go to
2019 Biological Evaluation of the Antiproliferative and Anti-migratory Activity of a Series of 3-(6-Phenylimidazo[2,1-b][1,3,4]thiadiazol-2-yl)-1H-indole Derivatives against Pancreatic Cancer Cells* Articolo in rivista Go to
2019 New 1,2,4-Oxadiazole Nortopsentin Derivatives with Cytotoxic Activity Articolo in rivista Go to
2018 An overview of recent molecular dynamics applications as medicinal chemistry tools for the undruggable site challenge Articolo in rivista Go to
2018 Synthesis of 5H-pyrido[3,2-b]pyrrolizin-5-one tripentone analogs with antitumor activity Articolo in rivista Go to
2018 Biofilm capability of staphylococcus strains isolated from food and the anti-biofilm activity of a chemically synthesized pyrrolomycin Articolo in rivista Go to
2018 New Thiazole Nortopsentin Analogues Inhibit Bacterial Biofilm Formation Articolo in rivista Go to
2018 A computational study to explore the molecular mechanisms behind the antiproliferative activity of Nortopsentin derivatives Proceedings Go to
2018 Bacterial Biofilm Inhibition in the Development of Effective Anti-Virulence Strategy Articolo in rivista Go to
2018 Proton-coupled folate transporter as a biomarker of outcome to treatment for pleural mesothelioma Articolo in rivista Go to
2017 Investigation of Isoindolo[2,1-a] quinoxaline-6-imines as Topoisomerase I Inhibitors with Molecular Modeling Methods Articolo in rivista Go to
2017 Antibacterial Activity of Desert Truffles from Saudi Arabia Against Staphylococcus aureus and Pseudomonas aeruginosa Articolo in rivista Go to
2017 Synthesis and antitumor activities of 1,2,3-triazines and their benzo- and heterofused derivatives Articolo in rivista Go to
2017 Synthesis, antitumor activity and CDK1 inhibiton of new thiazole nortopsentin analogues Articolo in rivista Go to
2017 Pyrrolo[3′,2′:6,7]cyclohepta[1,2-b]pyridines with potent photo-antiproliferative activity Articolo in rivista Go to
2017 An overview on the recent developments of 1,2,4-triazine derivatives as anticancer compounds Articolo in rivista Go to
2017 1,3,5-Triazines: A promising scaffold for anticancer drugs development Articolo in rivista Go to
2017 New antimicrobial peptides from Tirmania pinoyi and Terfezia boudieri in the struggle against antibiotic resistance Proceedings Go to
2017 New Tripentone Analogs with Antiproliferative Activity Articolo in rivista Go to
2017 Pharmaceutical Approaches to Target Antibiotic Resistance Mechanisms Articolo in rivista Go to
2016 A new class of phenylhydrazinylidene derivatives as inhibitors of Staphylococcus aureus biofilm formation Articolo in rivista Go to
2016 Discovery of a new class of sortase a transpeptidase inhibitors to tackle gram-positive pathogens: 2-(2-phenylhydrazinylidene)alkanoic acids and related derivatives Articolo in rivista Go to
2016 A peptide from human β thymosin as a platform for the development of new anti-biofilm agents for Staphylococcus spp. and Pseudomonas aeruginosa Articolo in rivista Go to
2016 Synthesis and antitumor activity of new thiazole nortopsentin analogs Articolo in rivista Go to
2016 Quality characteristics and in vitro digestibility study of barley flour enriched ditalini pasta Articolo in rivista Go to
2016 Synthesis and biofilm formation reduction of pyrazole-4-carboxamide derivatives in some Staphylococcus aureus strains Articolo in rivista Go to
2015 Curcumin derivatives as inhibitors of Gram positive and Gram negative biofilm formation Proceedings Go to
2015 Oregano essential oils activity against Listeria monocitogenes biofilms Proceedings Go to
2015 Sortase A Inhibitors: Recent Advances and Future Perspectives Articolo in rivista Go to
2015 Recent advanced in bioactive systems containing pyrazole fused with a five membered heterocycle Articolo in rivista Go to
2015 Synthesis, antiproliferative activity and possible mechanism of action of novel 2-acetamidobenzamides bearing the 2-phenoxy functionality Articolo in rivista Go to
2015 Discovery of a New Class of Sortase A Transpeptidase Inhibitors to Tackle Gram-positive Pathogens: 2-Phenylhydrazonoalkanoic Acid Derivatives Proceedings Go to
2015 Pharmaceutical potential of synthetic and natural pyrrolomycins Articolo in rivista Go to
2015 New Anti-Adhesion Agents In The Development of Antivirulence Drugs Proceedings Go to
2015 Synthesis and antiproliferative activity of 3-(2-cloroethyl)-5-methyl-6-phenyl-8-(trifluoromethyl)-5,6-dihydropyrazolo[3,4-f][1,2,3,5]tetrazepin-4-(3H)-one Articolo in rivista Go to
2014 Paracentrin 1, a synthetic antimicrobial peptide fragment of a beta-thymosin from the sea-urchin Paracentrotus lividus, interferes with staphylococcal and Pseudomonas aeruginosa biofilm formation Proceedings Go to
2014 Paracentrin1, a synthetic antimicrobial peptide fragment of a beta-thymosin from the sea-urchin Paracentrotus lividus, interferes whith staphylococcal and Pseudomonas aeruginosa biofilm formation Proceedings Go to
2014 Synthesis and antiproliferative activity of a natural like glucosyl polycyclic compound Proceedings Go to
2014 NUOVI DERIVATI 2-ACETAMMIDOBENZAMMIDICI: ATTIVITÀ ANTIPROLIFERATIVA E POSSIBILE MECCANISMO DI AZIONE Proceedings Go to
2014 Synthesis and antiproliferative activity of new derivatives containing the polycyclic system 5,7:7,13-dimethanopyrazolo[3,4-b]pyrazolo[3’,4’:2,3]azepino[4,5-f]azocine Articolo in rivista Go to
2014 Synthesis and antirpoliferative activity of isoxazolo[3,4-d]pyridazin-7(6H)-one derivatives Proceedings Go to
2014 Sortase A: An ideal target for anti-virulence drug development Articolo in rivista Go to
2014 Anti-adhesion agents against Gram-positive pathogens Articolo in rivista Go to
2014 The future of antibiotic: From the magic bullet to the smart bullet Articolo in rivista Go to
2014 ATTIVITÀ ANTIPROLIFERATIVA DI UN DERIVATO POLICICLICO CON STRUTTURA COMPLESSA Proceedings Go to
2013 2-cinnamamido, 2-(3-phenylpropiolamido) and 2-(3-phenylpropanamido)benzamides: synthesis, antiproliferative activity and mechanism of action Proceedings Go to
2012 Synthesis and anti-staphylococcal activity of new 4-diazopyrazole derivatives Articolo in rivista Go to
2012 Synthesis and antioproliferative activity of new derivatives containing the policyclic sistem 5,7:7,13-dimethanopyrazolo[3,4-b]pyrazolo[3'.4':2,3]azepino[4,5-f]azocine Proceedings Go to
2011 Synthesis and antiproliferative activity of indazole derivatives Proceedings Go to
2011 Synthesis of substituted 3-amino-N-phenyl-1H-indazole-1-carboxamides endowed with antiproliferative activity Articolo in rivista Go to
2011 Synthesis, antiproliferative activity, and mechanism of action of new benzamido derivatives Proceedings Go to
2011 Synthesis, antiproliferative activity, and mechanism of action of a series of 2-{[2E]-3-phenylprop-2-enoylamino}benzamides Articolo in rivista Go to
2010 Novel chemical countermeasures against staphylococcal biofilms Proceedings Go to
2010 Pyrazolobenzotriazinones Derivatives as COX Inhibitors: Synthesis Biological Activity and Molecular Modeling Studies Articolo in rivista Go to
2010 Pyrrolomycins as potential anti-staphylococcal biofilms agents Articolo in rivista Go to
2010 SYNTHESIS AND ANTIPROLIFERATIVE ACTIVITY OF 3-AMINO-N-PHENYL-1H-INDAZOLE-1-CARBOXAMIDES Proceedings Go to
2009 N-(INDAZOLYL)BENZAMIDO DERIVATIVES AS CDK1 INHIBITORS: DESIGN, SYNTHESIS, BIOLOGICAL ACTIVITY, AND MOLECULAR DOCKING STUDIES Articolo in rivista Go to
2009 Pyrazolo[3,4-d]pyrimidine Derivatives as COX-2 Selective Inhibitors: Synthesis and Molecular Modelling Studies Articolo in rivista Go to
2009 Synthesis and antiproliferative activity of 3-amino-N-phenyl-1H-indazole-1-carboxamides Articolo in rivista Go to
2009 Synthesis and biological evaluation of some new 2-phenylpropiolamidobenzamides as potential antagonists of the HDM2-p53 protein-protein interactions Proceedings Go to
2009 Pyrrolomycins as novel agents against staphylococcal biofilms Proceedings Go to
2008 4-Diazopyrazole Derivatives as Potential New Antibiofilm Agents Articolo in rivista Go to
2008 Synthesis and induction of G0-G1 phase arrest with apoptosis of 3,5-dimethyl-6-phenyl-8-(trifluoromethyl)-5,6-dihydropyrazolo[3,4-f][1,2,3,5]tetrazepin-4(3H)-one Articolo in rivista Go to
2008 SYNTHETIC AND BIOLOGICAL EVALUATION OF SOME NEW 2-CINNAMAMIDOBENZAMIDES AS POTENTIAL ANTAGONIST OF THE HDM2-P53 PROTEIN-PROTEIN INTERACTIONS Proceedings Go to
2008 In vitro anti-Gram-positive and anti-staphylococcal biofilm activity of newly halogenated pyrroles related to Pyrrolomycins Articolo in rivista Go to
2008 Comparative studies of the Pschorr reaction in the pyrazole series. Access to the new dibenzo(e,g)pyrazolo(1,5-a)(1,3)diazocine system of pharmaceutical interest Articolo in rivista Go to
2007 Synthesis and antiproliferative activity of 3-amino-N-phenyl-1H-indazole-1-carboxamide derivatives Proceedings Go to
2007 Synthesis and biological evaluation of new 2-{[(2E)-3-phenylprop-2-enoyl]amino}benzamides Proceedings Go to
2007 Synthesis and anticancer activity of 3-amino-N-phenyl-1H-indazole-1-carboxamide and 1-(1H)indazol-3-yl-3-phenylureido derivatives Proceedings Go to
2007 Synthesis and induction of G0-G1 phase arrest with apoptosis of 3,5-dimethyl-6-phenyl-8-trifluoromethyl-5,6-dihydropyrazolo[3,4-f][1,2,3,5]tetrazepin-4-one Proceedings Go to
2007 Antileukemic activity of some new 3-amino-N-phenyl-(1H)-indazole-1-carboxamide derivatives Proceedings Go to
2006 Synthesis of New Pyrazole Derivatives as Potential CDK1 Inhibitors Proceedings Go to
2006 Synthesis of New Indazol-3-yl derivatives as CDK1 inhibitors Proceedings Go to
2006 CDK: LigandFit Enrichment Plot of Active Compounds in a Screening Dataset. Proceedings Go to
2006 Synthesis of alkyl-5,8-dimethyl-6-phenyl-5,6-dihydropyrazolo[3,4-f][1,2,3,5]tetrazepin-4(3H)-ones of pharmaceutical interest Articolo in rivista Go to
2006 Synthesis and Antiproliferative Activity of a New Pyrazolo[3,4-f]1,2,3,5-tetrazepin-4(3H)-one Derivative Proceedings Go to
2006 Synthesis and antimicrobial activity of new bromine-rich pyrrole derivatives related to monodeoxypyoluteorin Articolo in rivista Go to
2005 BENZOTRIAZINONE AND QUINAZOLINONE DERIVATIVES AS COX-INHIBITORS: COMPUTATIONAL STUDIES Proceedings Go to
2004 SYNTHESIS AND ANTILEUKEMIC ACTIVITY OF NEW 3-(1-PHENYL-3-METHYLPYRAZOL-5-YL)-2-STYRYLQUINAZOLIN-4(3H)-ONES Articolo in rivista Go to
2004 Synthesis and antileukemic activity of new 3-(5-methylisoxazol-3-yl) and 3-(pyrimidin-2-yl)-2-styrylquinazolin-4(3H)-ones. Articolo in rivista Go to