Opportunità di Lavoro
Call per un Cluster Manager ALISEI
Il Cluster Tecnologico Nazionale Scienze della Vita ALISEI ha lanciato la call per un Cluster Manager. Qui tutte le informazioni utili per la presentazione delle candidature: https://www.clusteralisei.it/il-cluster-alisei-ha-lanciato-la-call-per-un-cluster-manager/
Borsa di studio post-lauream - Studi sulla matrice alimentare e sull'uomo
Programma di ricerca: Il programma della ricerca prevede due fasi: la prima sulla matrice alimentare (prodotto fresco raccolto in due tempi diversi e relativi trasformati); la seconda sul sangue dei soggetti arruolati per gli studi sull'uomo. La prima fase prevede la valutazione del contenuto polifenolico e delle proprietà antiossidanti del prodotto fresco (3 varietà) raccolto a due tempi diversi all'invaiatura ed a maturazione al fine di fornire i dati utili alla caratterizzazione nutrizionale e nutraceutica del prodotto; la seconda fase comprende campionamento per gli studi sull'uomo e le analisi biochimiche sul sangue dei soggetti arruolati. Le analisi saranno eseguite attraverso spettrofotometria UV/Visibile e Kit Elisa. Questo permetterà di valutare eventuali effetti positivi dei trasformati sulla salute umana. Infine si prevede l'elaborazione statistica dei risultati ottenuti e la partecipazione alla stesura di eventuali articoli scientifici.
Responsabile Scientifico: Prof. Pierangelo Sardo
Referente: Dott.ssa Danila Di Majo
Postdoc positions available - Cancer Metastasis and Exosomes - Weaver laboratory
The Weaver laboratory at Vanderbilt University is looking for motivated and Independent postdoctoral fellows to study how tumor and host cell exosomes drive cancer metastasis. Exosomes and other extracellular vesicles (EVs) carry autocrine and paracrine factors that promote cancer metastasis in multiple cancer types. The Weaver laboratory is actively investigating the underlylng mechanisms that account for the unique and critical activity of exosomes in laboratory has a strong background in exosome/EV biology, cell migration microenvironment, cell adheslon, cytoskeleton, membrane trafficking, live cell cellular and molecular driving metastasis. Our and metastasis, tumor imaging, mouse tumor models, and 3D culture. We also utilize bioinformatics analysis of large datasets (proteomics, RNA-Seq, TCGA, lipidomics) to Identify key EV cargoes connected to cancer aggressiveness. We are particularly recruiting early-stage postdoctoral fellows for projects focused on 1) head and neck cancer metastasis and 2) breast cancer metastasls.
For more information, please see our website: https://my.vanderbilt.edu/alissaweaver/
Candidates must be within 2 years of their terminal degree with a strong publication record. The ideal candidate will be highly motivated to develop their own research program and possess a Ph.D. degree with a strong background in blochemistry, molecular, and cellular biology, along with some knowledge of thecancer field. Experience with animal tumor models is also desirable. Good oral and written communication skills are required. Salary will be commensurate with experience and paid at NIH scale. Vanderbilt University is located in Nashville, Tennessee, a vibrant city with a strong artistic bent.
To apply, please contact Dr. Alissa Weaver at Alissa.weaver@vanderbilt.edu with your CV and a cover letter summarizing your research accomplishments, future goals, and why you are interested in postdoctoral training in the Weaver laboratory
Pre- and post-doctoral positions available in the lab of Dr. Marina Mione: The impact of the RNA sensing pathway in cancer
About the project:
We have discovered that cancers increase the production/accumulation of abnormal ncRNA, which activate the RNA sensing pathway in cells of the tumor microenvironment through extracellular vesicles (tEVs), (Biagini et al., submitted). The project, funded by AIRC (www.airc.it/english), aims at characterizing the effects of the RNA sensing pathway in tumors and associated immune cells using cell type specific approaches. We will identify the endogenous RNA species involved in signaling to the RNA sensing pathway, and the biogenesis of these ncRNA cargos in tEVs. We have fully funded post-doc and pre-doc/PhD positions to investigate the roles of the RNA sensing pathway in tumor progression and metastasis formation and identify drugs modulating this process.
About the team:
Our lab (http://www.cibio.unitn.it/465/laboratory-of-experimental-cancer-biology) is dedicated to the study of cancer cell biology, using zebrafish genetic models of cancer, complemented with human cancer cell models and patient samples. The zebrafish is an excellent vertebrate model for longitudinal studies of cancer progression, and allows for high resolution live imaging of cell biology events and high throughput genetic and chemical screens. In the last year we have developed tools for the study of the RNA sensing pathway in zebrafish [PMID: 33159854], performed precise genetic targeting of oncogenes and tumor suppressors in vivo [PMID: 33576334] and set up a fast and reliable method for the isolation of tEVs from zebrafish tumors (Biagini et al., submitted). Our lab is located in a very lively scientific environment, collaborating with many internal groups working on different aspects of cancer, engaged in several international collaborations and supported by “state-of-the-art” core facilities (https://www.cibio.unitn.it/).
About the candidates:
The pre-doctoral position should prepare for a fully funded PhD candidacy at the doctoral school of Biomolecular Sciences (https://www.unitn.it/drbs/17/phd-program) and will be available to candidates who have obtained a Master degree in Biomedical Studies less than one year ago (from March 2021 onwards). The post-doctoral position is available immediately to candidates holding a PhD or expected to get one in the next few months, initially for 1 year, renewable for an additional 2 years. The ideal candidate has experience in molecular biology, in vivo live imaging and/or analysis of NGS data. Experience in zebrafish and chemical screens are a plus, while enthusiasm for cancer biology is a must. A salary based on the Academic Italian guideline system and the experience/expertise of the successful candidate will be provided. Interested applicants should send a motivation letter, a detailed CV and the letter(s) of support of one (pre-doc) or two (post-doc) referees to: mariacaterina.mione@unitn.it
Dipartimento CIBIO – Avviso di selezione per il conferimento di n. 1 assegno di ricerca
È indetta una selezione per titoli ed eventuale colloquio per il conferimento n. 1 assegno per la collaborazione ad attività di ricerca dal titolo “Messa a punto e sviluppo di una tecnologia innovativa per identificare nuove molecole con attività antibatterica di interesse brevettuale” presso il Dipartimento CIBIO.
Researcher in Cancer Cell Biology University of Oslo – Department of Biosciences (IBV)
Position as Researcher available at the Department of Biosciences, Faculty of Mathematics and Natural Sciences, University of Oslo in the research group of Professor Cinzia Progida.
The position is for a period of 16 months.
The candidate for this position will work on a project funded by the Norwegian Cancer Society. The goal of this project is to identify and characterize molecules and pathways involved in lysosome transformation in cancer cells, and how this is coupled with the development of the cancer cell migratory and invasive ability. To achieve this, the project will make use of RNAi screens, proteomics, and advanced imaging techniques such as super-resolution and live imaging. Our group has access to the National imaging platform NorMIC Oslo, https://www.mn.uio.no/ibv/english/research/infrastructure/facilities/life-science/imaging/normic/ with a wide range of state-of-the-art imaging equipment. The Department of Biosciences harbors also an EM-lab, the Norwegian Sequencing Centre (NSC) and Proteomics services. The work includes collaboration with national and international groups and the candidate will have the possibility to spend a short visiting period in the lab of prof. Roberto Zoncu at the University of California, Berkeley.
Contact information
For further information please contact: Professor Cinzia Progida, e-mail: c.a.m.progida@ibv.uio.no, phone: +47 228 54441.
For questions regarding the recruitment system please contact: HR adviser Nina Holtan, e-mail: nina.holtan@mn.uio.no, phone: +47 228 54424.
ARCHIVIO OPPORTUNITA' DI LAVORO