Research Area

Active Research fields

Proteins which bind mRNA (RBP) encoding H1.0 and H3.3 histone variants in developing rat brain;

Production and release of extracellular vesicles (EV) by normal and tumor brain cells;   

Isolation of EVs from biological fluids in normal and pathological conditions;

Events controlling formation and maintenance of the blood brain barrier (BBB ) in in vitro systems;

Preparation of three-dimensional cultures of brain cells on poly-lactate scaffolds.

 

Research projects of the last 5 years

No national or international project.

Collaborations

Prof. Dr. Daniel Gygax

Hochschule für Life Sciences FHNW

Studiengangleiter MLS

Gründenstrasse 40

4132 Muttenz

Active research

The research group uses essentially the laboratories of the STEBICEF Department, which has laboratories for cultures of eukaryotic and prokaryotic cells, fluorescence microscopes, a confocal microscope, refrigerated centrifuges and ultracentrifuges, equipped with different types of rotors, sonicators , a laboratory equipped for the use of radioisotopes , micromanipulators, thermostatic baths, instruments for the amplification of nucleic acids , etc .

Services delivered under the right of third parties

In the last 5 years, the research group has been involved with searching cyplasin receptors on behalf of Cyplasin Biomedical Ltd (Prof. Petzelt). In general terms, the group has the know-how for applying biochemical and biomolecular methods.