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MONICA NOTARBARTOLO DI VILLAROSA

Curriculum e ricerca

Insegnamenti

Anno accademico Codice della materia Nome della materia CFU Corso di studi
2024/2025 01682 BIOTECNOLOGIE FARMACOLOGICHE 6 CHIMICA E TECNOLOGIA FARMACEUTICHE
2024/2025 03153 FARMACOLOGIA E FARMACOTERAPIA 8 CHIMICA E TECNOLOGIA FARMACEUTICHE
2024/2025 23617 FARMACOLOGIA E NUTRIZIONE 6 SCIENZE DELL'ALIMENTAZIONE E DELLA NUTRIZIONE UMANA

Pubblicazioni

Data Titolo Tipologia Scheda
2025 Design of innovative and low-cost dopamine-biotin conjugate sensor for the efficient detection of protein and cancer cells Articolo in rivista Vai
2024 Carrier capability of halloysite nanotubes for the intracellular delivery of antisense PNA targeting mRNA of neuroglobin gene Articolo in rivista Vai
2024 Citrus wastewater as a source of value‐added products: Quali‐quantitative analysis and in vitro screening on breast cancer cell lines Articolo in rivista Vai
2024 Vesicle-Transported Multidrug Resistance as a Possible Therapeutic Target of Natural Compounds Articolo in rivista Vai
2024 Comparison of Synthetic Pathways for Obtaining Fluorescent Nanomaterials Based on Halloysite and Carbon Dots for Potential Biological Sensing Articolo in rivista Vai
2024 Antimigratory effects of a new NF-κB inhibitor, (S)-b-salicyloylamino-a-exo-methylene-ƴ-butyrolactone, in 2D and 3D breast cancer models Articolo in rivista Vai
2023 Recovery of Bioactive Compounds from Marine Organisms: Focus on the Future Perspectives for Pharmacological, Biomedical and Regenerative Medicine Applications of Marine Collagen Review essay (rassegna critica) Vai
2023 Natural Inhibitors of P-glycoprotein in AcuteMyeloid Leukemia Review essay (rassegna critica) Vai
2022 Exploring the cellular uptake of hectorite clay mineral and its drug carrier capabilities Articolo in rivista Vai
2022 Antitumor Effect of Glandora rosmarinifolia (Boraginaceae) Essential Oil through Inhibition of the Activity of the Topo II Enzyme in Acute Myeloid Leukemia Articolo in rivista Vai
2022 Supramolecular Association of Halochromic Switches and Halloysite Nanotubes in Fluorescent Nanoprobes for Tumor Detection Articolo in rivista Vai
2022 Novel insights on [1,2]oxazolo[5,4‐e]isoindoles on multidrug resistant acute myeloid leukemia cell line Articolo in rivista Vai
2022 Phytol and Heptacosane Are Possible Tools to Overcome Multidrug Resistance in an In Vitro Model of Acute Myeloid Leukemia Articolo in rivista Vai
2022 Synthesis, In Vitro and In Silico Analysis of New Oleanolic Acid and Lupeol Derivatives against Leukemia Cell Lines: Involvement of the NF-κB Pathway Articolo in rivista Vai
2022 Nanocarrier based on halloysite and fluorescent probe for intracellular delivery of peptide nucleic acids Articolo in rivista Vai
2022 Prodrug based on halloysite delivery systems to improve the antitumor ability of methotrexate in leukemia cell lines Articolo in rivista Vai
2021 Patterns of Innate or Acquired Resistance to Anticancer Drugs: Our Experience to Overcome It Articolo in rivista Vai
2021 Bioactive triterpenes of protium heptaphyllum gum resin extract display cholesterol-lowering potential Articolo in rivista Vai
2021 In Vitro Modulation of P-Glycoprotein Activity by Euphorbia intisy Essential Oil on Acute Myeloid Leukemia Cell Line HL-60R Articolo in rivista Vai
2020 Cancer therapy and treatments during COVID-19 era Articolo in rivista Vai
2020 Abilities of β-Estradiol to interact with chemotherapeutic drugs, signal transduction inhibitors and nutraceuticals and alter the proliferation of pancreatic cancer cells Articolo in rivista Vai
2020 Can NF-κB Be Considered a Valid Drug Target in Neoplastic Diseases? Our Point of View Review essay (rassegna critica) Vai
2019 Essential Oil Composition of Alluaudia procera and in Vitro Biological Activity on Two Drug-Resistant Models Articolo in rivista Vai
2019 Targeting Multiple Myeloma with natural polyphenols Review essay (rassegna critica) Vai
2019 Cytotoxicity of oleanolic and ursolic acid derivatives toward hepatocellular carcinoma and evaluation of NF-κB involvement Articolo in rivista Vai
2019 Antitumor mechanism of the essential oils from two succulent plants in multidrug resistance leukemia cell Articolo in rivista Vai
2019 Essential oil of Cyphostemma juttae (Vitaceae): chemical composition and antitumor mechanism in triple negative breast cancer cells Articolo in rivista Vai
2019 Synthesis of Curcumin Derivatives and Analysis of Their Antitumor Effects in Triple Negative Breast Cancer (TNBC) Cell Lines Articolo in rivista Vai
2018 Chemical Composition, In Vitro Antitumor and Pro-Oxidant Activities of Glandora rosmarinifolia (Boraginaceae) Essential Oil Articolo in rivista Vai
2018 Potential Therapeutic Applications of MDA-9/Syntenin-NF-κB-RKIP Loop in Human Liver Carcinoma Articolo in rivista Vai
2017 NF-kB Is a Potential Molecular Drug Target in Triple-Negative Breast Cancers Articolo in rivista Vai
2015 Rash and multiorgan dysfunction following lamotrigine: could genetic be involved? Articolo in rivista Vai
2015 NF-κB is a potential pharmacological target in triple negative breast cancers. Proceedings Vai
2015 Epigenetic changes and nuclear factor-κB activation, but not microRNA-224, downregulate Raf-1 kinase inhibitor protein in triple‑negative breast cancer SUM 159 cells Articolo in rivista Vai
2014 Mechanisms of Raf-1 Kinase Inhibitor Protein Dysregulation in Triple-Negative Breast Cancers and Identification of Possible Novel Therapeutic Approaches for These Tumors Articolo in rivista Vai
2013 Analysis of pharmacologic approaches able to restore RKIP function in hepatocellular carcinoma Proceedings Vai
2013 Analysis of UGT1A1*28 and DPYD*2A polymorphisms in Sicilians patients with metastatic colorectal cancer treated with Irinotecan and 5-fluorouracil. Proceedings Vai
2013 Pharmacogenetic considerations for optimizing tacrolimus dosing in liver and kidney transplant patients Articolo in rivista Vai
2012 Unusual high dose of tacrolimus in liver transplant patient, a case report. Articolo in rivista Vai
2012 Analysis of Possible Mechanisms Accounting for Raf-1 Kinase Inhibitor Protein Downregulation in Hepatocellular Carcinoma Articolo in rivista Vai
2012 Alteration of signaling pathways in hepatocellular carcinoma: identification of new pharmacological targets and possible prognosis markers. Proceedings Vai
2012 Raf-1 Kinase Inhibitor Protein down-regulation in hepatocellular carcinoma: investigation of possible mechanisms Proceedings Vai
2011 Possible mechanisms of Raf-1 Kinase Inhibitor Protein down-regulation in hepatocellular carcinoma Proceedings Vai
2011 Influence of CYP3A5 and ABCB1 gene polymorphisms and other factors on tacrolimus dosing in Caucasian liver and kidney transplant patients. Articolo in rivista Vai
2011 Induction of Apoptosis and Chemosensitization by the Histone Deacetylase Inhibitor Trichostatin in Hepatocellular Carcinoma Cells: Molecular Analysis and RKIP Levels Articolo in rivista Vai
2011 Frequent Alteration of the Yin Yang 1/Raf-1 Kinase Inhibitory Protein Ratio in Hepatocellular Carcinoma Articolo in rivista Vai
2011 Restoration of Raf-1 Kinase Inhibitor Protein levels as a possible therapeutic approach in hepatocellular carcinoma. Proceedings Vai
2010 Yin Yang 1 and Raf-1 Kinase Inhibitory Protein Status in Hepatocellular Carcinoma: Future Perspectives Articolo in rivista Vai
2010 USE OF HERBAL REMEDIES AMONG CANCER AND TRANSPLANT PATIENTS IN THE TOWN OF PALERMO, SICILY Articolo in rivista Vai
2010 Altered Yin Yang 1/RAF-1 kinase inhibitory protein ratio as a possible molecular marker and therapeutic target in hepatocellular carcinoma Proceedings Vai
2010 Use of herbal products among cancer and transplanted patients in the town of Palermo,Sicily. Proceedings Vai
2010 Frequent alteration of the Yin Yang 1/Raf-1 Kinase Inhibitory Protein ratio in hepatocellular carcinoma Proceedings Vai
2009 Curcumin as a possible lead compound against hormone-independent, multidrug-resistant breast cancer Articolo in rivista Vai
2009 The effect of CYP3A5 and ABCB1 single nucleotide polymorphisms on tacrolimus dose requirements in Caucasian liver transplant patients Articolo in rivista Vai
2009 Prostaglandin E2 receptors and COX enzymes in human hepatocellular carcinoma: role in the regulation of cell growth Articolo in rivista Vai
2009 Lack of nucleophilic addition in the isoxazole and pyrazole diketone modified analogs of curcumin; implications for their antitumor and chemosensitizing activities. Articolo in rivista Vai
2009 ELABORATION OF CURCUMIN INTO DIKETONE MODIFIED ANALOGUES DEVOID OF NUCLEOPHILIC ADDITION CAPABILITY; IMPLICATIONS FOR THEIR ANTITUMOR AND CHEMOSENSITIZING ACTIVITIES Proceedings Vai
2008 Prostaglandin E2 receptors and COX enxymes in human hepatocellular carcinoma: role in the regulation of cell growth Proceedings Vai
2008 THE EFFECT OF CYP3A5 AND ABCB1 SINGLE NUCLEOTIDE POLYMORPHISMS ON TACROLIMUS DOSE REQUIREMENTS IN CAUCASIAN LIVER TRANSPLANT PATIENTS Proceedings Vai
2008 Plant polyphenols as possible lead compound against hormone-independent multidrug resistant breast cancer. Proceedings Vai
2008 Antitumor effects of curcumin and structurally beta-diketone modified analogs on multidrug resistant cancer cells Articolo in rivista Vai
2007 Effetti della curcumina e di suoi analoghi modificati al frammento beta-dichetone in cellule tumorali multifarmacoresistenti. Proceedings Vai
2007 Pro-oxidant and antitumor effects of curcumin and N-ethylmaleimide in the HA22T/VGH model Overt hepatocellular carcinoma. Proceedings Vai
2007 The antitumor activities of curcumin and its isoxazole analogue are not affected by multiple gene expression changes in an MDR model of the MCF-7 brest cancer cell line: Analysis of the possible molecular basis. Articolo in rivista Vai
2007 DISTRIBUTION OF CYP3A5 AND MDR-1 SINGLE NUCLEOTIDE POLYMORPHISMS IN CAUCASIAN LIVER TRANSPLANT PATIENTS Proceedings Vai
2006 Effects of the dietary polyphenols resveratrol and curcumin on the prevention and treatment of cancer. Proceedings Vai
2006 The NF-kB inhibitors curcumin and DHMEQ exert antitumor synergy with cisplatin in hepatic cancer cells. Analysis of relationship to IL-6 production. Proceedings Vai
2006 Effects of curcumin and related analogues on tumor cell lines expressing multiple mechanisms of drug resistance Proceedings Vai
2006 Effetti della curcumina e del suo derivato isossazolico in modelli di neoplasia multifarmacoresistente Proceedings Vai
2006 Significance of Autologous Interleukin-6 Production in the HA22T/VGH Cell Model of Hepatocellular Carcinoma Articolo in rivista Vai
2006 The selective cyclooxygenase-1 inhibitor SC-560 suppresses cell proliferation and induces apoptosis in human hepatocellular carcinoma cells Articolo in rivista Vai
2006 "Antitumor effects of the novel NF-kB inhibitor dehydroxymethylepoxyquinomicin (DHMEQ) on human hepatic cancer cells: analysis of synergy with cisplatin and of possible correlation with inhibition of pro-survival genes and IL-6 production”. Articolo in rivista Vai
2005 New trends in overcoming drug resistance in hepatocellular carcinoma. Looking for pharmacological inhibition of Inhibitory of Apoptosis Proteins (IAPs) by curcumin. Capitolo o Saggio Vai
2005 Induction of apoptosis by the adenosine derivative IB-MECA in parental or multidrug-resistant HL-60 leukemia cells: possibile relationship to the effects on inhibitor of apoptosis protein levels Articolo in rivista Vai
2005 Antitumor effects of curcumin in human hepatic cancer cells: Analysis of their relationship to inhibition of NF-kB and pro-survival gene expression. Altro Vai
2005 Antitumor effects of curcumin, alone or in combination with cisplatin, on hepatic cancer cells. Analysis of their relationship to IL-6 production Proceedings Vai
2005 ANTITUMOR EFFECTS OF CURCUMIN, ALONE OR IN COMBINATION WITH CISPLATIN OR DOXORUBICIN, ON HUMAN HEPATIC CANCER CELLS. ANALYSIS OF THEIR POSSIBLE RELATIONSHIP TO CHANGES IN NF-KB ACTIVATION LEVELS AND IAP GENE EXPRESSION Articolo in rivista Vai
2005 Antitumor effects of the NF-kB inhibitors curcumin and DHMEQ, alone or combined with cisplatin, on hepatic cancer cells. analysis of their relationship to IL-6 production. Proceedings Vai
2004 Induction of apoptosis and inhibition of cell growth in human hepatocellular carcinoma cells by COX-2 inhibitors Articolo in rivista Vai
2004 The selective COX-1 inhibitor SC-560 inhibits cell growth and induces apoptosis in human hepatocellular carcinoma cells Proceedings Vai
2004 Expression of the IAPs in multidrug resistant tumor cells Articolo in rivista Vai
2004 Induction of apoptosis by the proteasome inhibitor MG132 in human HCC cells: Possible correlation with specific caspase-dependent cleavage of β-catenin and inhibition of β-catenin-mediated transactivation Articolo in rivista Vai
2004 Ihnibitor of Apoptosis Proteins (IAPs) as a new possible therapeutic targets in hepatocellular cancer. Proceedings Vai
2004 Expression of IAPs (Inhibitory of Apoptosis Proteins) and of their alternative splice variants in hepatocellular carcinoma tissues and cells Articolo in rivista Vai
2004 Antitumor effects of curcumin and of its combination with cisplatin or doxorubicin on human hepatic cancer cells: possible relationship to NF-kB activation and IAP gene expression. Proceedings Vai
2004 Expression of WISPs and of their novel alternative variants in human hepatocellular carcinoma cells Articolo in rivista Vai
2004 Resistance to gemcitabine in a lymphoma cell line resistant to Fas-mediated apoptosis Articolo in rivista Vai
2002 Expression of HIP/PAP mRNA in Human Hepatoma Cell Lines Articolo in rivista Vai