| 2025 |
RNA editing applied to cystic fibrosis: RESTORE can target G542X CFTR mRNA and revert the nonsense mutation |
Articolo in rivista |
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| 2024 |
RESCUING P53 BY NEW TRANSLATIONAL
READTHROUGH INDUCING DRUGS |
Abstract in atti di convegno pubblicato in volume |
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| 2024 |
Promoting readthrough of nonsense mutations in CF mouse model: Biodistribution and efficacy of NV848 in rescuing CFTR protein expression |
Articolo in rivista |
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| 2023 |
Readthrough Approach Using NV Translational Readthrough-Inducing Drugs (TRIDs): A Study of the Possible Off-Target Effects on Natural Termination Codons (NTCs) on TP53 and Housekeeping Gene Expression |
Articolo in rivista |
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| 2023 |
Investigating the inhibition of FTSJ1 a tryptophan tRNA-specific
2’-O-methyltransferase by NV TRIDs, as a mechanism of readthrough in
nonsense mutated CFTR |
Articolo in rivista |
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| 2023 |
RNA Editing Approaches for the correction of nonsense mutation in a cell model for Cystic Fibrosis |
Abstract in atti di convegno pubblicato in volume |
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| 2023 |
Site-Specific RNA Editing of Stop Mutations in the CFTR mRNA of Human Bronchial Cultured Cells |
Articolo in rivista |
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| 2023 |
Controlled uptake of PFOA in adult specimens of Paracentrotus lividus and evaluation of gene expression in their gonads and embryos |
Articolo in rivista |
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| 2022 |
Readthrough Inducing Drugs (TRIDs) in human fibroblasts harboring the c.5047 C>T (R1683*) nonsense mutation |
Abstract in atti di convegno pubblicato in volume |
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| 2022 |
Preliminary genetic characterisation of Southern Smooth Snake Coronella girondica (Serpentes, Colubridae) populations in Italy, with some considerations on their alpine distribution |
Articolo in rivista |
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| 2022 |
Nonsense codons suppression. An acute toxicity study of three optimized TRIDs in murine model, safety and tolerability evaluation |
Articolo in rivista |
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| 2022 |
P015 Translational readthrough inducing drugs: a study of toxicity in mice models and in vitro safety validation of the specific readthrough process. |
Contributo in atti di convegno pubblicato in rivista |
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| 2022 |
Phylogenetic affinities of the Italian population of Eastern Montpellier snake, Malpolon insignitus (Serpentes: Lamprophiidae) |
Articolo in rivista |
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| 2022 |
Uptake and photoinduced degradation of phthalic acid esters (PAEs) in Ulva lactuca highlight its potential application in environmental bioremediation |
Articolo in rivista |
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| 2022 |
Impact of Heavy Metals in Eggs and Tissues of C. caretta along the Sicilian Coast (Mediterranean Sea) |
Articolo in rivista |
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| 2021 |
Presence and biodistribution of perfluorooctanoic acid (PFOA) in Paracentrotus lividus highlight its potential application for environmental biomonitoring |
Articolo in rivista |
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| 2021 |
Can phthalates move into the eggs of the loggerhead sea turtle Caretta caretta? The case of the nests on the Linosa Island in the Mediterranean Sea |
Articolo in rivista |
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| 2020 |
Pharmacophore-Based Design of New Chemical Scaffolds as Translational Readthrough-Inducing Drugs (TRIDs) |
Lettera |
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| 2020 |
Investigating CRISPR-CAS13b as a tool for the RNA editing of CFTR mRNA with premature stop codon |
Contributo in atti di convegno pubblicato in rivista |
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| 2020 |
Targeting nonsense: Optimization of 1,2,4-oxadiazole trids to rescue cftr expression and functionality in cystic fibrosis cell model systems |
Articolo in rivista |
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| 2020 |
Investigating REPAIRv2 as a Tool to Edit CFTR mRNA with Premature Stop Codons |
Articolo in rivista |
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| 2020 |
The genetic identity of the only Italian population of the genus Macroprotodon Guichenot, 1850 on the island of Lampedusa, Sicily |
Articolo in rivista |
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| 2020 |
Phylogenetic relationships of the italian populations of horseshoe whip snake hemorrhois hippocrepis (Serpentes, colubridae) |
Articolo in rivista |
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| 2019 |
Strategies against nonsense: oxadiazoles as translational readthrough-inducing drugs (TRIDs) |
Review essay (rassegna critica) |
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| 2019 |
Caffeine boosts Ataluren's readthrough activity |
Articolo in rivista |
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| 2018 |
OXADIAZOLE DERIVATIVES FOR THE TREATMENT OF GENETIC DISEASES DUE TO NONSENSE MUTATIONS |
Brevetto |
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| 2018 |
Rescuing the CFTR protein function: Introducing 1,3,4-oxadiazoles as translational readthrough inducing drugs |
Articolo in rivista |
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| 2017 |
Optimization of a new lead promoting the readthrough of the nonsense mutations for CFTR rescue in human CF cells |
Poster pubblicato in volume |
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| 2017 |
Tracking the invasion of the red swamp crayfish Procambarus clarkii (Girard, 1852) (Decapoda Cambaridae) in Sicily: a “citizen science” approach |
Articolo in rivista |
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| 2016 |
Exploring the readthrough of nonsense mutations by non-acidic Ataluren analogues selected by ligand-based virtual screening |
Articolo in rivista |
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| 2016 |
Novel molecules for the readthrough of PTCs in biological model systems and in cystic fibrosis cells |
Abstract in atti di convegno pubblicato in volume |
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| 2016 |
Identification and validation of novel molecules obtained by integrated computational and experimental approaches for the read-through of PTCs in CF cells |
Abstract in rivista |
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| 2016 |
Identification of a putative regulator of early-histone gene expression of Paracentrotus lividus |
Abstract in atti di convegno pubblicato in volume |
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| 2015 |
Premature termination codon 124 derivatives as a novel approach to improve the read-through of premature amber and ochre stop codons |
Articolo in rivista |
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| 2015 |
Identification of a putative GAGA factor in P. lividus embryos |
Proceedings |
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| 2015 |
Integrated computational and experimental approaches for the identification of new molecules with readthrough activity on premature termination codons (PTCs) in cystic fibrosis cells |
Proceedings |
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| 2015 |
Identification and validation of novel molecules obtained by integrated computational and experimental approaches for the read-through of PTCs in CF cells. |
Proceedings |
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| 2015 |
Enhancement of premature stop codon readthrough in the CFTR gene by Ataluren (PTC124) derivatives |
Articolo in rivista |
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| 2014 |
Toward a Rationale for the PTC124 (Ataluren) Promoted Readthrough of Premature Stop Codons: A Computational Approach and GFP-Reporter Cell-Based Assay |
Articolo in rivista |
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| 2014 |
Identification and validation of novel molecules obtained by integrated computational and experimental approaches for the readthrough of PTCs in CF cells |
Proceedings |
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| 2014 |
Reevaluating the function of a transcription factor: MBF-1 as a sea urchin chromatin organizer ? |
Proceedings |
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| 2013 |
Valutazione dell'azione readthorough della molecola PTC124 su sistemi modello cellulari contenenti mutazioni non senso e in cellule epiteliali bronchiali IB3.1 (delF508/W1282X) derivate da pazienti affetti da fibrosi cistica. |
Proceedings |
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| 2013 |
PTC124 DERIVATIVES AS A NOVEL APPROACH TO IMPROVE THE READTHROUGH OF PREMATURE AMBER AND OCHRE STOP CODONS |
Proceedings |
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| 2013 |
The Compass-like Locus, Exclusive to the Ambulacrarians, Encodes a Chromatin Insulator Binding Protein in the Sea Urchin Embryo |
Articolo in rivista |
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| 2013 |
PTC124 derivatives as a novel approach to improve the readthrough of premature stop codons in the CFTR gene |
Proceedings |
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| 2013 |
AZIONE READTHROUGH DI DERIVATI DEL PTC124 SU SISTEMI MODELLO CELLULARI E IN CELLULE DI EPITELIO BRONCHIALE-FC IB3.1 (CFTR F508/W1282X ) |
Proceedings |
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| 2012 |
X CONVENTION OF INVESTIGATORS IN CYSTIC FIBROSIS. |
Proceedings |
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| 2011 |
PTC124 derivatives as a novel approach to improve the readthrough of premature stop codons in the CFTR gene. |
Proceedings |
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| 2009 |
The sea urchin histone H2A enhancer-binding protein MBF-1 is needed for maximal expression also for the H3 gene, while is buffered by the sns5 insulator on its interaction with the downstream H1 promoter. |
Proceedings |
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| 2009 |
Enhancer, chromatin insulator, non-coding RNA and α-histone gene expression during
embryogenesis of the sea urchin Paracentrotus lividus. |
Proceedings |
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| 2009 |
Promoter activity of the sea urchin (Paracentrotus lividus) nucleosomal H3 and H2A and linker H1 a-histone genes is modulated by enhancer and chromatin insulator |
Articolo in rivista |
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| 2007 |
Characterization of a nuclear factor associated to the chromatin of sea urchin histone genes |
Proceedings |
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| 2007 |
Constitutive Promoter Occupancy by the MBF-1 Activator and Chromatin Modification of the Developmental Regulated Sea Urchin alpha-H2A Histone Gene |
Articolo in rivista |
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| 2006 |
Dinamica della cromatina nella regolazione del gene con homeobox Hbox12 in P. lividus. |
Proceedings |
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| 2006 |
CHOMATIN DYNAMIC AND REGULATION OF GENE
EXSPRESSION IN THE SEA URCHIN EMBRYO |
Proceedings |
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| 2005 |
“Epigenetics of silencing of Paracentrotus lividus α-H2A gene” |
Proceedings |
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| 2004 |
Down regulation of early sea urchin histone H2A gene relies on cis regulative sequences located in the 5’ and 3’ regions and including the enhancer blocker sns |
Articolo in rivista |
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| 2004 |
Ruolo delle HDAC sul silenziamento genico nell’embrione di riccio di mare |
Proceedings |
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| 2004 |
LA DINAMICA DELLA CROMATINA NELLA REGOLAZIONE DELL’ESPRESSIONEGENICA DELL’EMBRIONE DI RICCIO DI MARE |
Proceedings |
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| 2003 |
Assembly of Polycomb complexes and silencing mechanisms |
Articolo in rivista |
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| 2002 |
Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites |
Articolo in rivista |
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| 2001 |
Establishment of Polycomb silencing requires a transient interaction between PC and ESC |
Articolo in rivista |
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| 2001 |
The sea urchin sns insulator blocks CMV enhancer following integration in human cells |
Articolo in rivista |
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| 2000 |
Homeobox genes and sea urchin development |
Articolo in rivista |
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| 2000 |
Functional characterization of the enhancer blocking element of the sea urchin early histone gene cluster reveals insulator properties and three essential cis-acting sequences |
Articolo in rivista |
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| 1999 |
Regulation of the sea urchin early H2A histone gene expression depends on the modulator element and on sequences located near the 3' end |
Articolo in rivista |
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| 1999 |
Spatially restricted expression of PlOtp, a Paracentrotus lividus Orthopedia-related homeobox gene, is correlated with oral ectodermal patterning and skeletal morphogenesis in late-cleavage sea urchin embryos |
Articolo in rivista |
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| 1997 |
Sea urchin HSF activity in vitro and in transgenic embryos |
Articolo in rivista |
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| 1997 |
Enhancer blocking activity located near the 3′ end of the sea urchin early H2A histone gene |
Articolo in rivista |
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| 1997 |
Gene expression during early embryogenesis of sea urchin: The histone and homeobox genes |
Contributo in atti di convegno pubblicato in rivista |
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| 1995 |
Homeobox-containing gene transiently expressed in a spatially restricted pattern in the early sea urchin embryo |
Articolo in rivista |
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| 1994 |
Expression of homeobox-containing genes in the sea urchin (Parancentrotus lividus) embryo |
Articolo in rivista |
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