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ALESSANDRA MONTALBANO

Curriculum e ricerca

Insegnamenti

Anno accademico Codice della materia Nome della materia CFU Corso di studi
2024/2025 09065 ANALISI DEI MEDICINALI I 10 FARMACIA
2024/2025 22967 NUOVI APPROCCI CHIMICO-FARMACEUTICI PER CONTRASTARE L'ANTIBIOTICO RESISTENZA 6 FARMACEUTICA E NUTRACEUTICA ANIMALE

Pubblicazioni

Data Titolo Tipologia Scheda
2024 Identification of 6,9-dihydro-5H-pyrrolo[3,2-h]quinazolines as a new class of F508del-CFTR correctors for the treatment of cystic fibrosis Articolo in rivista Vai
2024 Citrus wastewater as a source of value‐added products: Quali‐quantitative analysis and in vitro screening on breast cancer cell lines Articolo in rivista Vai
2024 Chaperoning system: Intriguing target to modulate the expression of CFTR in cystic fibrosis Articolo in rivista Vai
2023 Novel tricyclic pyrrolo-quinolines as pharmacological correctors of the mutant CFTR chloride channel Articolo in rivista Vai
2023 Identification of pyrrolo[3′,4’:3,4]cyclohepta[1,2-d][1,2]oxazoles as promising new candidates for the treatment of lymphomas Articolo in rivista Vai
2023 Insight into non-nucleoside triazole-based systems as viral polymerases inhibitors Review essay (rassegna critica) Vai
2023 HSV-1 Glycoprotein D and Its Surface Receptors: Evaluation of Protein–Protein Interaction and Targeting by Triazole-Based Compounds through In Silico Approaches Articolo in rivista Vai
2023 Exploring the anticancer activity and the mechanism of action of pyrrolomycins F obtained by microwave-assisted total synthesis Articolo in rivista Vai
2022 GPCR Inhibition in Treating Lymphoma Review essay (rassegna critica) Vai
2022 Novel insights on [1,2]oxazolo[5,4‐e]isoindoles on multidrug resistant acute myeloid leukemia cell line Articolo in rivista Vai
2022 Synthesis of 2H-Imidazo[2′,1':2,3] [1,3]thiazolo[4,5-e]isoindol-8-yl-phenylureas with promising therapeutic features for the treatment of acute myeloid leukemia (AML) with FLT3/ITD mutations Articolo in rivista Vai
2022 New tricyclic systems as photosensitizers towards triple negative breast cancer cells Articolo in rivista Vai
2022 Transcriptome and computational analysis assess the anti-tubulin activity of [1,2]oxazole derivatives in lymphoma Abstract in atti di convegno pubblicato in rivista Vai
2022 The New Microtubule-Targeting Agent SIX2G Induces Immunogenic Cell Death in Multiple Myeloma Articolo in rivista Vai
2022 Development of [1,2]oxazoloisoindoles tubulin polymerization inhibitors: Further chemical modifications and potential therapeutic effects against lymphomas Articolo in rivista Vai
2022 Insight on pyrimido[5,4-g]indolizine and pyrimido[4,5-c]pyrrolo[1,2-a]azepine systems as promising photosensitizers on malignant cells Articolo in rivista Vai
2021 Recurrence of the oxazole motif in tubulin colchicine site inhibitors with anti-tumor activity Review essay (rassegna critica) Vai
2021 Insight on [1,3]thiazolo[4,5-e]isoindoles as tubulin polymerization inhibitors Articolo in rivista Vai
2021 Pyrrolidine in Drug Discovery: A Versatile Scaffold for Novel Biologically Active Compounds Review essay (rassegna critica) Vai
2021 NEW THERAPEUTIC AGENTS FOR THE TREATMENT OF HAEMATOLOGICAL PATHOLOGIES Brevetto Vai
2021 Evaluation of Fused Pyrrolothiazole Systems as Correctors of Mutant CFTR Protein Articolo in rivista Vai
2020 Pyrrolo[2',3':3,4]cyclohepta[1,2-d][1,2]oxazoles, a New Class of Antimitotic Agents Active against Multiple Malignant Cell Types Articolo in rivista Vai
2020 Evaluation of [1,2]oxazolo[5,4-e]isoindoles in lymphoma cells Abstract in atti di convegno pubblicato in rivista Vai
2020 Bioactive pyrrole-based compounds with target selectivity Articolo in rivista Vai
2020 Marine Anticancer Agents: An Overview with a Particular Focus on Their Chemical Classes Articolo in rivista Vai
2020 Current development of CFTR potentiators in the last decade Articolo in rivista Vai
2019 Synthesis and photocytotoxic activity of [1,2,3]triazolo[4,5-h][1,6]naphthyridines and [1,3]oxazolo[5,4-h][1,6]naphthyridines Articolo in rivista Vai
2019 An overview on chemical structures as ΔF508-CFTR correctors Review essay (rassegna critica) Vai
2019 NUOVI AGENTI TERAPEUTICI PER IL TRATTAMENTO DI PATOLOGIE EMATOLOGICHE Brevetto Vai
2019 Targeting Multiple Myeloma with natural polyphenols Review essay (rassegna critica) Vai
2019 Furocoumarins as multi-target agents in the treatment of cystic fibrosis Review essay (rassegna critica) Vai
2019 Quality, functional and sensory evaluation of pasta fortified with extracts from Opuntia ficus-indica cladodes Articolo in rivista Vai
2018 New Thiazole Nortopsentin Analogues Inhibit Bacterial Biofilm Formation Articolo in rivista Vai
2018 Synthesis of 5H-pyrido[3,2-b]pyrrolizin-5-one tripentone analogs with antitumor activity Articolo in rivista Vai
2017 Investigation of Isoindolo[2,1-a] quinoxaline-6-imines as Topoisomerase I Inhibitors with Molecular Modeling Methods Articolo in rivista Vai
2017 Synthesis, antitumor activity and CDK1 inhibiton of new thiazole nortopsentin analogues Articolo in rivista Vai
2017 Synthesis and antitumor activities of 1,2,3-triazines and their benzo- and heterofused derivatives Articolo in rivista Vai
2017 Pyrrolo[3′,2′:6,7]cyclohepta[1,2-b]pyridines with potent photo-antiproliferative activity Articolo in rivista Vai
2017 An overview on the recent developments of 1,2,4-triazine derivatives as anticancer compounds Articolo in rivista Vai
2017 1,3,5-Triazines: A promising scaffold for anticancer drugs development Articolo in rivista Vai
2017 New Tripentone Analogs with Antiproliferative Activity Articolo in rivista Vai
2017 Pharmaceutical Approaches to Target Antibiotic Resistance Mechanisms Articolo in rivista Vai
2016 Synthesis and antitumor activity of new 7-azaindole derivative nortopsentin analogues Abstract in atti di convegno pubblicato in volume Vai
2016 Synthesis and antiproliferative mechanism of action of pyrrolo[3′,2′:6,7] cyclohepta[1,2-d]pyrimidin-2-amines as singlet oxygen photosensitizers Articolo in rivista Vai
2016 Preclinical Activity of New [1,2]Oxazolo[5,4-e]isoindole Derivatives in Diffuse Malignant Peritoneal Mesothelioma Articolo in rivista Vai
2016 Quality characteristics and in vitro digestibility study of barley flour enriched ditalini pasta Articolo in rivista Vai
2016 Pyrrolocycloheptaoxazole as potent antitumor agents Abstract in atti di convegno pubblicato in volume Vai
2016 Synthesis and antitumor activity of new thiazole nortopsentin analogs Articolo in rivista Vai
2016 [1,2]Oxazolo[5,4-e]isoindoles as promising tubulin polymerization inhibitors Articolo in rivista Vai
2015 3-[4-(1H-indol-3-yl)-1,3-thiazol-2-yl]-1H-pyrrolo[2,3-b]pyridines, nortopsentin Analogues with antiproliferative activity Articolo in rivista Vai
2015 Pyrazolo[3,4-h]quinolines promising photosensitizing agents in the treatment of cancer Articolo in rivista Vai
2015 Quality characteristic and in vitro digestibility study of barley flour enriched ditalini pasta Proceedings Vai
2015 Aza-isoindolo and isoindolo-azaquinoxaline derivatives with antiproliferative activity Articolo in rivista Vai
2015 Synthesis and antiproliferative activity of thiazolyl-bis-pyrrolo[2,3-b]pyridines and indolyl-thiazolyl-pyrrolo[2,3-c]pyridines, nortopsentin analogues Articolo in rivista Vai
2015 [1,2]oxazole[5,4-e]isoindoles as promising drugs for anticancer chemotherapy Proceedings Vai
2015 Synthesis of isoindolo[1,4]benzoxazinone and isoindolo[1,5]benzoxazepine: two new ring systems of pharmaceutical interest Articolo in rivista Vai
2015 Water-soluble isoindolo[2,1-a]quinoxalin-6-imines: In vitro antiproliferative activity and molecular mechanism(s) of action Articolo in rivista Vai
2015 Sistemi triciclici azotati ad attività fotochemioterapica Proceedings Vai
2014 In vitro digestion of beta glucan enriched pasta and antioxidant potential of digesta Proceedings Vai
2014 In vitro digestion of beta glucan enriched pasta: polysaccharide molecular characterization and antioxidant activity of bioaccessible fraction. Proceedings Vai
2014 ‘Interrupted’ diazotization of 3-aminoindoles and 3-aminopyrroles Articolo in rivista Vai
2014 Synthesis and biological evaluation of pyrrolo[3’,2’:6,7]cyclohepta[1,2-d]pyrimidin-2-amines Proceedings Vai
2014 11H‑Pyrido[3′,2′:4,5]pyrrolo[3,2‑c]cinnoline and Pyrido[3′,2′:4,5]pyrrolo[1,2‑c][1,2,3]benzotriazine: Two New Ring Systems with Antitumor Activity Articolo in rivista Vai
2014 Synthesis of the New Ring System Bispyrido[4',3':4,5]pyrrolo [1,2-a:1',2'-d]pyrazine and Its Deaza Analogue Articolo in rivista Vai
2014 Synthesis of substituted isoindolo[2,1-a]quinoxalin-6-yl–amino and 6-imino-5-yl thiourea derivatives Articolo in rivista Vai
2014 Synthesis of a new class of pyrrolo[3,4-h]quinazolines with antimitotic activity Articolo in rivista Vai
2014 Synthesis of thiazolo[5,4-b]pyridine and [1,3]thiazolo[5,4-h][1,6]naphthyridin-8-one derivatives as potential m-TOR inhibitors Proceedings Vai
2014 Synthesis and antiproliferative activity of substituted 3[2-(1H-indol-3-yl)-1,3-thiazol-4-yl]-1H-pyrrolo[3,2-b]pyridines, marine alkaloid nortopsentin analogues Articolo in rivista Vai
2013 Synthesis of [1,2]oxazolo[5,4-e]indazoles as antitumour agents Articolo in rivista Vai
2013 Synthesis of the new oligopeptide pyrrole derivative isonetropsin and its one pyrrole unit analogue Articolo in rivista Vai
2013 Convenient synthesis of pyrrolo[3,4-g]indazole Articolo in rivista Vai
2013 Novel 1H‑Pyrrolo[2,3‑b]pyridine Derivative Nortopsentin Analogues: Synthesis and Antitumor Activity in Peritoneal Mesothelioma Experimental Models Articolo in rivista Vai
2012 Antitumor activity of 2,5-bis-(3’-indolyl)-pyrroles, deaza-analogues of Nortopsentins Proceedings Vai
2012 Synthesis and Antiproliferative Activity of the Ring System[1,2]Oxazolo[4,5-g]indole Articolo in rivista Vai
2012 An efficient synthesis of pyrrolo[3',2':4,5]thiopyrano[3,2-b]pyridin-2-one: a new ring system of pharmaceutical interest Articolo in rivista Vai
2012 New topoisomerase I inhibitors with condensed-azaindole structure Proceedings Vai
2011 Pyrrolo[3,4-h]quinolinones a new class of photochemotherapeutic agents Articolo in rivista Vai
2011 Synthesis of 5-substituted 2,3-dihydrobenzofurans in a one-pot oxidation/ cyclization reaction Articolo in rivista Vai
2011 3-CHLOROETHYL-PYRROLO[2,1-D][1,2,3,5]TETRAZINES: SYNTHESIS AND ANTITUMOR ACTIVITY Proceedings Vai
2011 Synthesis and Antitumor Activity of 3-(2-Phenyl-1,3-thiazol-4-yl)-1H-indoles and 3-(2-Phenyl-1,3-thiazol-4-yl)-1H-7-azaindoles Articolo in rivista Vai
2011 Nucleophilic substitutions in the isoindole series as a valuable tool to synthesize derivatives with antitumor activity Articolo in rivista Vai
2011 Isoxazolo[5,4-e]isoindole a new ring system with potent antitumor activity Proceedings Vai
2011 Pyrrolo[3,2-h]quinazolines as Photochemotherapeutic Agents Articolo in rivista Vai
2011 Synthesis of the new ring system pyrrolizino[2,3-b]indol-4(5H)-one Articolo in rivista Vai
2010 SYNTHESIS OF PYRROLO[3,2-H]QUINOLINONES WITH GOOD PHOTOCHEMOTHERAPEUTIC ACTIVITY AND NO DNA DAMAGE Articolo in rivista Vai
2010 SYNTHESIS AND ANTITUMOR ACTIVITY OF 3-[2-PHENYL-1,3-THIAZOL-4-YL]-1H-7-AZAINDOLES Proceedings Vai
2010 PYRROLO[3,4-H]QUINAZOLINES WITH ANTITUMOR ACTIVITY Proceedings Vai
2009 AMINO-HETEROCYCLES AS SYNTHONS FOR THE SYNTHESIS OF POTENTIAL ANTICANCER AGENTS Proceedings Vai
2009 NORTOPSENTIN HETEROANALOGUES: SYNTHESES AND ANTITUMOR ACTIVITY Proceedings Vai
2009 Pyrido[4′,3′:4,5]pyrrolo[2,1-d][1,2,3,5]tetrazines, a new class of Temozolomide heteroanalogues Articolo in rivista Vai
2009 PYRAZOLO[3,4-h]QUINOLIN-2-ONES WITH POTENTIAL ANTITUMOR ACTIVITY Proceedings Vai
2009 NUCLEOPHILIC SUBSTITUTIONS IN ISOINDOLE SERIES AS VALUABLE TOOL TO SYNTHESIZE DERIVATIVES WITH ANTITUMOR ACTIVITY Proceedings Vai
2009 Pyrido[2’,3’:4,5]pyrrolo[2,1-d][1,2,3,5]tetrazine-4(3H)-ones, a new class of temozolomide heteroanalogues Articolo in rivista Vai
2009 TRICYCLIC HETEROCYCLES WITH ANTIPROLIFERATIVE ACTIVITY Proceedings Vai
2009 Synthesis of the New Ring System 2-Oxo-[1,4]oxazino[3,2-e]indole, Heteroanalogue of Angelicin Articolo in rivista Vai
2008 PYRROLO[3,4-H]QUINOLIN-2-ONES AS NEW POTENTIAL PHOTOCHEMOTERAPEUTIC DRUGS Proceedings Vai
2008 SYNTHESIS OF NEW OLIGOPEPTIDE PYRROLE DERIVATIVES Proceedings Vai
2008 THIOPYRANO[2,3-E]INDOL-2-ONES: ANGELICIN HETEROANALOGUES WITH POTENT PHOTOANTIPROLIFERATIVE ACTIVITY Articolo in rivista Vai
2008 ISOINDOLO[2,1-a]QUINOXALINE DERIVATIVES, NOVEL POTENT ANTITUMOR AGENTS WITH DUAL INHIBITION OF TUBULIN POLYMERIZATION AND TOPOISOMERASE I Articolo in rivista Vai
2008 4-AZAINDOLE[2,1-D][1,3,5]TETRAZINE-4(3H)-ONES, A NEW CLASS OF AZOLOTETRAZINES AS POTENTIAL ANTITUMOR AGENTS Proceedings Vai
2007 7-AZAINDOLO[1,2-c][1,2,3]BENZOTRIAZINA UN NUOVO SISTEMA ETEROCICLICO A POTENZIALE ATTIVITA’ ANTITUMORALE Proceedings Vai
2007 DNA minor groove binders: an overview on molecular modeling and QSAR approaches Articolo in rivista Vai
2007 SINTESI ED ATTIVITÀ ANTITUMORALE DI ANALOGHI PENTATOMICI DELLA NORTOPSENTINA Proceedings Vai
2007 SINTESI DI 2,5-BIS[3-(7-AZAINDOLIL)]TIOFENI ANALOGHI DELLA NORTOPSENTINA Proceedings Vai
2007 5H-Pirido[3’,2’:4,5]Pirrolo[3,2-c]Cinnolina un Nuovo Sistema Eterociclico a Potenziale Attività Antitumorale Proceedings Vai
2007 Synthesis and Antitumor Properties of 2,5-Bis(3'-indolyl) thiophenes: Analogues of Marine Alkaloid Nortopsentin Articolo in rivista Vai
2007 SINTESI DI NUOVI DERIVATI[2,3-E]ISOINDOL-2-ONI A POTENZIALE ATTIVITA' FOTOCHEMIOTERAPICA Proceedings Vai
2007 SYNTHESIS OF 3,5-BIS(3'-INDOLYL)ISOXAZOLES, ANALOGUES OF MARINE ALKALOID NORTOPSENTIN Proceedings Vai
2007 SYNTHESIS OF PYRROLO[3,4-H]QUINAZOLIN-2-ONE A NEW RING SYSTEM WITH POTENTIAL PHOTOTHERAPEUTIC ACTIVITY Proceedings Vai
2007 4-AZA E 7-AZA-ISOINDOLO[1,2-a]CHINOSSALINE: DUE NUOVI SISTEMI ETEROCICLICI A POTENZIALE ATTIVITÀ ANTITUMORALE Proceedings Vai
2007 ISOINDOLO[2,1-C]BENZO[1,2,4]TRIAZINES: A NEW RING SYSTEM WITH ANTIPROLIFERATIVE ACTIVITY Articolo in rivista Vai
2007 PYRROLO[3,4-G]INDAZOLE A NEW RING SYSTEM WITH POTENTIAL ANTITUMOR ACTIVITY Proceedings Vai
2006 SYNTHESIS OF 2,5-BIS(3'-INDOLYL)-FURANS, ANALOGUES OF NORTOPSENTIN Proceedings Vai
2006 A synthetic approach to new polycyclic ring system of biologial interest through domino reaction: indolo[2,3-e][1,2,3]triazolo[1,5-a]pyrimidine Articolo in rivista Vai
2006 SYNTHESIS OF 2,5-BIS(3'-INDOLYL)-PYRROLES, DEAZA-ANALOGUES OF NORTOPSENTIN Proceedings Vai
2006 Sintesi del Nuovo Sistema Eterociclico 7-Azaindolocinnolinico come Potenziale Agente Antineoplastico Proceedings Vai
2006 PYRANO[2,3-E]ISOINDOL-2-ONE: A NEW RING SYSTEM WITH POTENTIAL PHOTOBIOLOGICAL PROPERTIES Proceedings Vai
2006 A Multivariate Analysis of HIV-1 Protease Inhibitors and Resistance Induced by Mutation Articolo in rivista Vai
2006 MADoSPRO: a new Approach to Molecular Modelling Studies on a Series of DNA Minor Groove Binders Articolo in rivista Vai
2006 PYRROLO[2,3-H]QUINOLINONES: A NEW RING SYSTEM WITH POTENT PHOTOANTIPROLIFERATIVE ACTIVITY Articolo in rivista Vai
2006 Molecular modelling studies on new series of DNA-interactive annelated pyrrolo-pyrimidines Proceedings Vai
2006 Sintesi ed Attività Antitumorale di Bis(indolil)eterocicli: Analoghi dell’Alcaloide Marino Nortopsentina Proceedings Vai
2006 SINTESI DELL'ISONETROPSINA E DELL'ISOMERO DIMERICO DELLA DISTAMICIA A Proceedings Vai
2006 A multivariate analysis on HIV-1 protease inhibitors and resistance induced by mutation Proceedings Vai
2005 2-OXO-[1,4]OXAZINO[3,2-E]INDOLE: A NEW RING SYSTEM WITH POTENTIAL PHOTOBIOLOGICAL PROPERTIES Proceedings Vai
2005 1-Methyl-3H-pyrazolo[1,2-a]benzo[1,2,3,4]tetrazin-3-ones. Design, Synthesis, and Biological Activity of New Antitumor Agents Articolo in rivista Vai
2005 In House Methodology to Assign the Mechanism of Action of New Annelated Triazolopyrimidine Derivatives with Anticancer Activity Proceedings Vai
2005 New Tricyclic System of Biological Interest Thieno[3,2-e][1,2,3]triazolo[1,5-a]pyrimidine Trough Domino Reactions of 2-Azidothiophene. Proceedings Vai
2005 Annelated Pyrrolo-pyrimidines from Amino-cyanopyrroles and BMMAs as Leads for New DNA-interactive Ring Systems Articolo in rivista Vai
2005 HIV-1 Protease Inhibitors and Resistance Induced by Mutation. Correlation between Multivariate Analysis and Molecular Docking. Proceedings Vai
2005 A new Approach to Molecular Modelling Studies on a Series of DNA Minor Groove Binders Articolo in rivista Vai
2005 Isoindolo[1,2-a]quinoxaline derivatives with potent antitumor activity. Proceedings Vai
2005 Synthesis and Antiproliferative Activity of [1,2,3,5]tetrazino[5,4-a]indoles, a New Class of Azolo-tetrazinones Articolo in rivista Vai
2005 SYNTHESIS OF 3,5-BIS(3'-INDOLYL)PYRAZOLES, ANALOGUES OF NORTOPSENTIN Proceedings Vai
2005 SYNTHESIS AND PHOTOCHEMIOTHERAPEUTIC ACTIVITY OF THIOPYRANO[2,3-E]INDOL-2-ONES Articolo in rivista Vai
2005 2,5-bis(3'-Indolyl)thiophenes, Analogues of Marine Alkaloid Nortopsentin. Proceedings Vai
2004 Docking of indolo- and pyrrolo-pyrimidines to DNA. New DNA-interactive polycycles from amino-indoles/pyrroles and BMMA. Articolo in rivista Vai
2004 Sintesi di Oligopeptidi Pirrolici Isomeri della Distamicina e della Netropsina Proceedings Vai
2004 Sintesi di Oligopeptidi Pirrolici Isomeri della Distamicina e della Netropsina Proceedings Vai
2004 Molecular Modelling Studies on New Series of DNA-Interactive annelated Pyrrolo-pyrimidines Proceedings Vai
2004 Studi di Molecular Modelling su Derivati del Nuovo Sistema Eterociclico DNA-interattivo Isoindolo[2,1-c]benzo[1,2,4]triazina Proceedings Vai
2004 Studi di Modellistica Molecolare e Sintesi di Sistemi Indolotriazolopirimidinici Proceedings Vai
2004 A multivariate analysis on non-nucleoside HIV-1 reverse transcriptase inhibitors and resistance induced by mutation Articolo in rivista Vai
2004 “QSPR, Sintesi ed Attività Biologica di Nuovi Derivati del Sistema Tetraciclico Indolo[3,2-e][1,2,3]triazolo[1,5-a]pirimidinico.” Proceedings Vai
2004 Synthesis and Antiproliferative Activity of [1,2,4]triazino[4,3-a]indoles Articolo in rivista Vai
2004 Studi di Docking su Isomeri della Distamicina e della Netropsina Proceedings Vai
2004 Sintesi di Nuovi Derivati 2,5-bis(3’Indolil)tiofeni, Analoghi dell’Alcaloide Marino Nortopsentina. Proceedings Vai
2004 Sintesi ed Attivita’ Fotobiologica di Tiopirano[2,3-c]indol-2-oni Proceedings Vai
2004 Pirrolo[3,4-h]chinolinoni: Potenziali Agenti Fotochemioterapici Proceedings Vai