| 2024 |
Antimigratory effects of a new NF-κB inhibitor, (S)-b-salicyloylamino-a-exo-methylene-ƴ-butyrolactone, in 2D and 3D breast cancer models |
Articolo in rivista |
Vai |
| 2024 |
Citrus wastewater as a source of value‐added products: Quali‐quantitative analysis and in vitro screening on breast cancer cell lines |
Articolo in rivista |
Vai |
| 2024 |
Vesicle-Transported Multidrug Resistance as a Possible Therapeutic Target of Natural Compounds |
Articolo in rivista |
Vai |
| 2023 |
Natural Inhibitors of P-glycoprotein in AcuteMyeloid Leukemia |
Review essay (rassegna critica) |
Vai |
| 2022 |
Antitumor Effect of Glandora rosmarinifolia (Boraginaceae) Essential Oil through Inhibition of the Activity of the Topo II Enzyme in Acute Myeloid Leukemia |
Articolo in rivista |
Vai |
| 2022 |
Synthesis, In Vitro and In Silico Analysis of New Oleanolic Acid and Lupeol Derivatives against Leukemia Cell Lines: Involvement of the NF-κB Pathway |
Articolo in rivista |
Vai |
| 2022 |
Novel insights on [1,2]oxazolo[5,4‐e]isoindoles on multidrug resistant acute myeloid leukemia cell line |
Articolo in rivista |
Vai |
| 2022 |
Phytol and Heptacosane Are Possible Tools to Overcome Multidrug Resistance in an In Vitro Model of Acute Myeloid Leukemia |
Articolo in rivista |
Vai |
| 2021 |
In Vitro Modulation of P-Glycoprotein Activity by Euphorbia intisy Essential Oil on Acute Myeloid Leukemia Cell Line HL-60R |
Articolo in rivista |
Vai |
| 2021 |
Patterns of Innate or Acquired Resistance to Anticancer Drugs: Our Experience to Overcome It |
Articolo in rivista |
Vai |
| 2020 |
Can NF-κB Be Considered a Valid Drug Target in Neoplastic Diseases? Our Point of View |
Review essay (rassegna critica) |
Vai |
| 2019 |
Synthesis of Curcumin Derivatives and Analysis of Their Antitumor Effects in Triple Negative Breast Cancer (TNBC) Cell Lines |
Articolo in rivista |
Vai |
| 2019 |
Cytotoxicity of oleanolic and ursolic acid derivatives toward hepatocellular carcinoma and evaluation of NF-κB involvement |
Articolo in rivista |
Vai |
| 2019 |
Essential oil of Cyphostemma juttae (Vitaceae): chemical composition and antitumor mechanism in triple negative breast cancer cells |
Articolo in rivista |
Vai |
| 2019 |
Antitumor mechanism of the essential oils from two succulent plants in multidrug resistance leukemia cell |
Articolo in rivista |
Vai |
| 2019 |
Essential Oil Composition of Alluaudia procera and in Vitro Biological Activity on Two Drug-Resistant Models |
Articolo in rivista |
Vai |
| 2018 |
Potential Therapeutic Applications of MDA-9/Syntenin-NF-κB-RKIP Loop in Human Liver Carcinoma |
Articolo in rivista |
Vai |
| 2018 |
Chemical Composition, In Vitro Antitumor and Pro-Oxidant Activities of Glandora rosmarinifolia (Boraginaceae) Essential Oil |
Articolo in rivista |
Vai |
| 2017 |
NF-kB Is a Potential Molecular Drug Target in Triple-Negative Breast Cancers |
Articolo in rivista |
Vai |
| 2016 |
Chemical and pharmaceutical evaluation of the relationship between triazole linkers and pore size on cyclodextrin–calixarene nanosponges used as carriers for natural drugs |
Articolo in rivista |
Vai |
| 2015 |
Rash and multiorgan dysfunction following lamotrigine: could genetic be involved? |
Articolo in rivista |
Vai |
| 2015 |
NF-κB is a potential pharmacological target in triple negative breast cancers. |
Proceedings |
Vai |
| 2015 |
Epigenetic changes and nuclear factor-κB activation, but not microRNA-224, downregulate Raf-1 kinase inhibitor protein in triple‑negative breast cancer SUM 159 cells |
Articolo in rivista |
Vai |
| 2014 |
Mechanisms of Raf-1 Kinase Inhibitor Protein Dysregulation in Triple-Negative Breast Cancers and Identification of Possible Novel Therapeutic Approaches for These Tumors |
Articolo in rivista |
Vai |
| 2013 |
Analysis of pharmacologic approaches able to restore RKIP function in hepatocellular carcinoma |
Proceedings |
Vai |
| 2013 |
Analysis of UGT1A1*28 and DPYD*2A polymorphisms in Sicilians patients with metastatic colorectal cancer treated with Irinotecan and 5-fluorouracil. |
Proceedings |
Vai |
| 2013 |
Expression of a specific Thymidylate synthase polimorfic allele in metastatic colorectal patients is regulated by Myeloid Zinc Finger 1. |
Proceedings |
Vai |
| 2013 |
Pharmacogenetic considerations for optimizing tacrolimus
dosing in liver and kidney transplant patients |
Articolo in rivista |
Vai |
| 2012 |
Analysis of Possible Mechanisms Accounting for Raf-1 Kinase Inhibitor Protein Downregulation in Hepatocellular Carcinoma |
Articolo in rivista |
Vai |
| 2012 |
ANALISI DEI POLIMORFISMI DEI GENI CODIFICANTI PER L'ENZIMA UDP-GLUCURONILTRANSFERASI (UGT) E PER L'ENZIMA DIIDROPIRIMIDINA DEIDROGENASI (DPD), CORRELATI A MAGGIORE TOSSICITA' IN SEGUITO A TRATTAMENTO, RISPETTIVAMENTE, CON IRINOTECANO E CON 5-FLUOROURACILE IN SOGGETTI CON TUMORE COLON RETTALE (CRC). |
Tesi di dottorato pre 2013 |
Vai |
| 2012 |
Alteration of signaling pathways in hepatocellular carcinoma: identification of new pharmacological targets and possible prognosis markers. |
Proceedings |
Vai |
| 2012 |
Raf-1 Kinase Inhibitor Protein down-regulation in hepatocellular carcinoma: investigation of possible mechanisms |
Proceedings |
Vai |
| 2012 |
Design and synthesis of hybrid drugs based on curcumin scaffold |
Proceedings |
Vai |
| 2012 |
Unusual high dose of tacrolimus in liver transplant patient, a case report. |
Articolo in rivista |
Vai |
| 2012 |
Analisi dei polimorfismi dei geni codificanti per l’enzima
UDP-glucuronosiltrasferasi (UGT) e per l’enzima diidropirimidina
deidrogenasi (DPD), correlati a maggiore tossicità in seguito a
trattamento, rispettivamente, con Irinotecano e con 5-Fluorouracile in
soggetti con tumore colon rettale (CRC) |
Tesi di dottorato pre 2013 |
Vai |
| 2011 |
Possible mechanisms of Raf-1 Kinase Inhibitor Protein down-regulation in hepatocellular carcinoma |
Proceedings |
Vai |
| 2011 |
Restoration of Raf-1 Kinase Inhibitor Protein levels as a possible therapeutic approach in hepatocellular carcinoma. |
Proceedings |
Vai |
| 2011 |
Influence of CYP3A5 and ABCB1 gene polymorphisms and other factors on tacrolimus dosing in Caucasian liver and kidney transplant patients. |
Articolo in rivista |
Vai |
| 2011 |
Induction of Apoptosis and Chemosensitization by the Histone Deacetylase Inhibitor Trichostatin in Hepatocellular Carcinoma Cells: Molecular Analysis and RKIP Levels |
Articolo in rivista |
Vai |
| 2011 |
Frequent Alteration of the Yin Yang 1/Raf-1 Kinase Inhibitory Protein Ratio in Hepatocellular Carcinoma |
Articolo in rivista |
Vai |
| 2010 |
Altered Yin Yang 1/RAF-1 kinase inhibitory protein ratio as a possible molecular marker and therapeutic target in hepatocellular carcinoma |
Proceedings |
Vai |
| 2010 |
Frequent alteration of the Yin Yang 1/Raf-1 Kinase Inhibitory Protein ratio in hepatocellular carcinoma |
Proceedings |
Vai |
| 2010 |
Yin Yang 1 and Raf-1 Kinase Inhibitory Protein Status in Hepatocellular Carcinoma: Future Perspectives |
Articolo in rivista |
Vai |
| 2009 |
Lack of nucleophilic addition in the isoxazole and pyrazole diketone modified analogs of curcumin; implications for their antitumor and chemosensitizing activities. |
Articolo in rivista |
Vai |
| 2009 |
The effect of CYP3A5 and ABCB1 single nucleotide polymorphisms on tacrolimus dose requirements in Caucasian liver transplant patients |
Articolo in rivista |
Vai |
| 2009 |
ELABORATION OF CURCUMIN INTO DIKETONE MODIFIED ANALOGUES DEVOID OF NUCLEOPHILIC ADDITION CAPABILITY; IMPLICATIONS FOR THEIR ANTITUMOR AND CHEMOSENSITIZING ACTIVITIES |
Proceedings |
Vai |
| 2009 |
Curcumin as a possible lead compound against hormone-independent, multidrug-resistant breast cancer |
Articolo in rivista |
Vai |
| 2009 |
Potential role of the natural multi-targeted agent curcumin in the treatment of oral diseases. |
Articolo in rivista |
Vai |
| 2008 |
Antitumor effects of curcumin and structurally beta-diketone modified analogs on multidrug resistant cancer cells |
Articolo in rivista |
Vai |
| 2008 |
Plant polyphenols as possible lead compound against hormone-independent multidrug resistant breast cancer. |
Proceedings |
Vai |
| 2008 |
THE EFFECT OF CYP3A5 AND ABCB1 SINGLE NUCLEOTIDE POLYMORPHISMS ON TACROLIMUS DOSE REQUIREMENTS IN CAUCASIAN LIVER TRANSPLANT PATIENTS |
Proceedings |
Vai |
| 2007 |
Effetti della curcumina e di suoi analoghi modificati al frammento beta-dichetone in cellule tumorali multifarmacoresistenti. |
Proceedings |
Vai |
| 2007 |
The antitumor activities of curcumin and its isoxazole analogue are not affected by multiple gene expression changes in an MDR model of the MCF-7 brest cancer cell line: Analysis of the possible molecular basis. |
Articolo in rivista |
Vai |
| 2007 |
The antitumor activities of curcumin and of its novel isoxazole analogue MR 39 are not hampered by the multidrug resistant condition of tumor cells expressing both P-glycoprotein and different inhibitory of apoptosis proteins |
Proceedings |
Vai |
| 2007 |
DISTRIBUTION OF CYP3A5 AND MDR-1 SINGLE NUCLEOTIDE POLYMORPHISMS IN CAUCASIAN LIVER TRANSPLANT PATIENTS |
Proceedings |
Vai |
| 2007 |
Pro-oxidant and antitumor effects of curcumin and N-ethylmaleimide in the HA22T/VGH model Overt hepatocellular carcinoma. |
Proceedings |
Vai |
| 2006 |
“Antitumor and molecular effects of curcumin and of its isoxazole analogue on multidrug resistant breast cancer cells. New perspectives in tumor theraphy: molecular aspects, 2006”. |
Capitolo o Saggio |
Vai |
| 2006 |
Significance of autologous interleukin 6 production in the HA22T/VGH model of hepatocellular carcinoma |
Articolo in rivista |
Vai |
| 2006 |
"Antitumor effects of the novel NF-kB inhibitor dehydroxymethylepoxyquinomicin (DHMEQ) on human hepatic cancer cells: analysis of synergy with cisplatin and of possible correlation with inhibition of pro-survival genes and IL-6 production”. |
Articolo in rivista |
Vai |
| 2006 |
Effects of curcumin and related analogues on tumor cell lines expressing multiple mechanisms of drug resistance |
Proceedings |
Vai |
| 2006 |
The NF-kB inhibitors curcumin and DHMEQ exert antitumor synergy with cisplatin in hepatic cancer cells. Analysis of relationship to IL-6 production. |
Proceedings |
Vai |
| 2006 |
Effetti della curcumina e del suo derivato isossazolico in modelli di neoplasia multifarmacoresistente |
Proceedings |
Vai |
| 2006 |
Effects of the dietary polyphenols resveratrol and curcumin on the prevention and treatment of cancer. |
Proceedings |
Vai |
| 2006 |
Le attività antitumorali della curcumina e del suo più potente analogo isossazolico non sono compromesse dal pattern di espressione genica della variante MDR della linea di carcinoma mammario MCF-7 |
Proceedings |
Vai |
| 2006 |
Significance of Autologous Interleukin-6 Production in the HA22T/VGH Cell Model of Hepatocellular Carcinoma |
Articolo in rivista |
Vai |
| 2005 |
New trends in overcoming drug resistance in hepatocellular carcinoma. Looking for pharmacological inhibition of Inhibitory of Apoptosis Proteins (IAPs) by curcumin. |
Capitolo o Saggio |
Vai |
| 2005 |
Antitumor effects of curcumin, alone or in combination with cisplatin, on hepatic cancer cells. Analysis of their relationship to IL-6 production |
Proceedings |
Vai |
| 2005 |
Antitumor effects of curcumin in human hepatic cancer cells: Analysis of their relationship to inhibition of NF-kB and pro-survival gene expression. |
Altro |
Vai |
| 2005 |
Antitumor effects of the NF-kB inhibitors curcumin and DHMEQ, alone or combined with cisplatin, on hepatic cancer cells. analysis of their relationship to IL-6 production. |
Proceedings |
Vai |
| 2005 |
Induction of apoptosis by the adenosine derivative IB-MECA in parental or multidrug-resistant HL-60 leukemia cells: possibile relationship to the effects on inhibitor of apoptosis protein levels |
Articolo in rivista |
Vai |
| 2005 |
Antitumor effects of the grape stilbenes resveratrol and piceatannol on multidrug and apoptosis resistant HL60 leukemia cells" |
Proceedings |
Vai |
| 2004 |
Curva da carico orale di metionina nella valutazione di pazienti affetti da patologia trombotica |
Proceedings |
Vai |
| 2004 |
Expression of WISPs and of their novel alternative variants in human hepatocellular carcinoma cells |
Articolo in rivista |
Vai |
| 2004 |
Evaluations and new relationship between renal failure and homocysteine plasma levels in patients with chronic renal failure. |
Proceedings |
Vai |
| 2004 |
Plasma homocysteine levels in patients with chronic renal failure |
Proceedings |
Vai |
| 2004 |
Plasma homocysteine levels in patients with chronic renal failure. |
Proceedings |
Vai |
| 2004 |
Evaluation of patients with thrombotic stroke by methionine loading oral curve |
Proceedings |
Vai |
| 2004 |
Plasma omocysteine levels in patients with chronic renal failure |
Proceedings |
Vai |
| 2004 |
Evaluations and new relationships between renal failure and homocysteine plasma levels in patients with chronic renal failure |
Proceedings |
Vai |
| 2004 |
Induction of apoptosis by the proteasome inhibitor MG132 in human HCC cells: Possible correlation with specific caspase-dependent cleavage of β-catenin and inhibition of β-catenin-mediated transactivation |
Articolo in rivista |
Vai |
