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VALENTINA GUARNOTTA

Curriculum e ricerca

Insegnamenti

Anno accademico Codice della materia Nome della materia CFU Corso di studi
2024/2025 02993 ENDOCRINOLOGIA (MODULO) 3 MEDICINA E CHIRURGIA

Pubblicazioni

Data Titolo Tipologia Scheda
2024 CONVENTIONAL GLUCOCORTICOID REPLACEMENT THERAPY VS. DUAL-RELEASE HYDROCORTISONE: EFFECTS ON INFLAMMATION AND IMMUNE PROFILE IN PATIENTS WITH PRIMARY ADRENAL INSUFFICIENCY AND IMPLICATIONS OF THERAPY RESPONSE PREDICTORS Abstract in atti di convegno pubblicato in rivista Vai
2023 Ultrasound Parameters Can Accurately Predict the Risk of Malignancy in Patients with "Indeterminate TIR3b" Cytology Nodules: A Prospective Study Articolo in rivista Vai
2023 Practical therapeutic approach in the management of diabetes mellitus secondary to Cushing's syndrome, acromegaly and neuroendocrine tumours Review essay (rassegna critica) Vai
2023 Evidence of greater severity of diabetic foot ulcers during COVID-19 pandemic: A real-life single-centre cohort study Articolo in rivista Vai
2023 Editorial: Obesity and cancer: update on etiology, molecular biomarkers and biotargets, clinical strategies, and epidemiology Nota o commento Vai
2023 Neuroendocrine neoplasms in the context of inherited tumor syndromes: a reappraisal focused on targeted therapies Articolo in rivista Vai
2023 Gender-related differences in patients with carcinoid syndrome: new insights from an Italian multicenter cohort study Articolo in rivista Vai
2023 Role of Mediterranean diet in endocrine diseases: a joint overview by the endocrinologist and the nutritionist Review essay (rassegna critica) Vai
2023 Irisin: A Possible Marker of Adipose Tissue Dysfunction in Obesity Articolo in rivista Vai
2023 Nutritional Intervention in Cushing's Disease: The Ketogenic Diet's Effects on Metabolic Comorbidities and Adrenal Steroids Articolo in rivista Vai
2022 Correction to: Neuroendocrine neoplasms in the context of inherited tumor syndromes: a reappraisal focused on targeted therapies Nota a sentenza Vai
2022 Prediction of diabetes mellitus induced by steroid overtreatment in adrenal insufficiency. Articolo in rivista Vai
2022 Impact of Chemical Endocrine Disruptors and Hormone Modulators on the Endocrine System Review essay (rassegna critica) Vai
2022 Long-term outcomes of conventional and novel steroid replacement therapy on bone health in primary adrenal insufficiency Articolo in rivista Vai
2022 Myoinositol supplementation in the treatment of gestational diabetes mellitus: effects on glycaemic control and maternal-foetal outcomes Articolo in rivista Vai
2022 Metabolic Profile in a Cohort of Young Sicilian Patients with Klinefelter's Syndrome: The Role of Irisin Articolo in rivista Vai
2022 Gender-specific soluble α-klotho levels as marker of GH deficiency in children: a case-control study Articolo in rivista Vai
2022 Impact of Chemical Endocrine Disruptors and Hormone Modulators on the Endocrine System Review essay (rassegna critica) Vai
2022 Neuroendocrine Tumors: A Comprehensive Review on Nutritional Approaches Review essay (rassegna critica) Vai
2022 COVID-19 and the Pancreas: A Narrative Review Review essay (rassegna critica) Vai
2022 Vitamin D Deficiency in Cushing's Disease: Before and After Its Supplementation Articolo in rivista Vai
2022 Very Low-Calorie Ketogenic Diet: A Potential Application in the Treatment of Hypercortisolism Comorbidities Review essay (rassegna critica) Vai
2022 Incretin Response to Mixed Meal Challenge in Active Cushing's Disease and after Pasireotide Therapy Articolo in rivista Vai
2021 Pathology Reporting in Neuroendocrine Neoplasms of the Digestive System: Everything You Always Wanted to Know but Were Too Afraid to Ask Articolo in rivista Vai
2021 Maternal-foetal complications in pregnancy: a retrospective comparison between type 1 and type 2 diabetes mellitus. Articolo in rivista Vai
2021 Correction to: One Year of Dapaglifozin Add-On Therapy Ameliorates Surrogate Indexes of Insulin Resistance and Adiposity in Patients with Type 2 Diabetes Mellitus Nota o commento Vai
2021 One Year of Dapaglifozin Add-On Therapy Ameliorates Surrogate Indexes of Insulin Resistance and Adiposity in Patients with Type 2 Diabetes Mellitus Articolo in rivista Vai
2021 Diabetic foot ulcers: Retrospective comparative analysis from Sicily between two eras Articolo in rivista Vai
2021 Metabolic comorbidities of adrenal insufficiency: Focus on steroid replacement therapy and chronopharmacology. Articolo in rivista Vai
2021 Effects of GLP-1 receptor agonists on myokine levels and pro-inflammatory cytokines in patients with type 2 diabetes mellitus Articolo in rivista Vai
2021 Emerging therapies in pheochromocytoma and paraganglioma: Immune checkpoint inhibitors in the starting blocks Articolo in rivista Vai
2021 Predictive factors of polycystic ovary syndrome in girls with precocious pubarche Articolo in rivista Vai
2021 Microbiota Gut-Brain Axis in Ischemic Stroke: A Narrative Review with a Focus about the Relationship with Inflammatory Bowel Disease. Articolo in rivista Vai
2021 Case Report: Unmasking Hypercalcemia in Patients With Neuroendocrine Neoplasms. Experience From Six Italian Referral Centers. Articolo in rivista Vai
2021 Levothyroxine and insulin requirement in autoimmune polyglandular type 3 syndrome: a real-life study Articolo in rivista Vai
2021 Glucocorticoid excess and COVID-19 disease Articolo in rivista Vai
2021 Are diabetes and its medications risk factors for the development of COVID-19? Data from a population-based study in Sicily. Articolo in rivista Vai
2020 Anti-Inflammatory Action of Heterogeneous Nuclear Ribonucleoprotein A2/B1 in Patients with Autoimmune Endocrine Disorders Articolo in rivista Vai
2020 Circulating Irisin Levels as a Marker of Osteosarcopenic-Obesity in Cushing’s Disease Articolo in rivista Vai
2020 Clinical and hormonal characteristics in heterozygote carriers of congenital adrenal hyperplasia Articolo in rivista Vai
2020 From microbiota toward gastro-enteropancreatic neuroendocrine neoplasms: Are we on the highway to hell? Articolo in rivista Vai
2020 ENDOCRINE TUMOURS: Calcitonin in thyroid and extra-thyroid neuroendocrine neoplasms: the two-faced Janus. Articolo in rivista Vai
2020 Tenapanor for the treatment of irritable bowel syndrome with constipation. Articolo in rivista Vai
2020 Epidemiology of pancreatic neuroendocrine neoplasms: a gender perspective. Articolo in rivista Vai
2019 Dual-release hydrocortisone improves hepatic steatosis in patients with secondary adrenal insufficiency: A real-life study Articolo in rivista Vai
2019 The medical treatment with pasireotide in Cushing’s disease: an Italian multicentre experience based on “real-world evidence” Articolo in rivista Vai
2019 Immune checkpoint blockade for Merkel cell carcinoma: actual findings and unanswered questions Articolo in rivista Vai
2019 Therapeutic sequences in patients with grade 1−2 neuroendocrine tumors (NET): an observational multicenter study from the ELIOS group Articolo in rivista Vai
2019 Circulating Irisin Levels in Children with GH Deficiency before and after 1 Year of GH Treatment Articolo in rivista Vai
2019 Dual-release hydrocortisone vs conventional glucocorticoids in adrenal insufficiency Articolo in rivista Vai
2018 The metabolic outcomes of growth hormone treatment in children are gender specific Articolo in rivista Vai
2018 Valutazione dell’insulino-sensibilità tramite clamp euglicemico iperinsulinemico in bambini in terapia sostitutiva con GH. Proceedings Vai
2018 Improved cardiovascular and cardiometabolic risk in patients with type 1 diabetes and autoimmune polyglandular syndrome switched from glargine to degludec due to hypoglycaemic variability Articolo in rivista Vai
2018 Insulin sensitivity and secretion and adipokine profile in patients with Cushing’s disease treated with pasireotide Articolo in rivista Vai
2018 Growth hormone and hematopoiesis: A retrospective analysis on a large cohort of children with growth hormone deficiency Articolo in rivista Vai
2018 The Zollinger-Ellison syndrome: is there a role for somatostatin analogues in the treatment of the gastrinoma? Articolo in rivista Vai
2018 Pasireotide treatment reduces cardiometabolic risk in Cushing’s disease patients: an Italian, multicenter study Articolo in rivista Vai
2018 Hepatic steatosis index in acromegaly: Correlation with insulin resistance regardless of the disease control Articolo in rivista Vai
2018 Miglioramento clinico e metabolico in pazienti affetti da diabete mellito tipo 1 associato ad altre endocrinopatie (APS) dopo shift della terapia insulinica basale con glargine a degludec Proceedings Vai
2018 Comparison between euglycemic hyperinsulinemic clamp and surrogate indices of insulin sensitivity in children with growth hormone deficiency Articolo in rivista Vai
2018 Improved insulin sensitivity and secretion in prediabetic patients with adrenal insufficiency on dual-release hydrocortisone treatment: a 36-month retrospective analysis Articolo in rivista Vai
2018 Higher cardiometabolic risk in idiopathic versus autoimmune type 1 diabetes: A retrospective analysis Articolo in rivista Vai
2018 Effects of pasireotide treatment on coagulative profile: a prospective study in patients with Cushing’s disease Articolo in rivista Vai
2018 Pasireotide versus pituitary surgery: a retrospective analysis of 12 months of treatment in patients with Cushing's disease Articolo in rivista Vai
2018 Efficacy of combined treatment with pasireotide, pegvisomant and cabergoline in an acromegalic patient resistant to other treatments: a case report Articolo in rivista Vai
2018 Maggiore rischio cardiometabolico in pazienti di razza non caucasica affetti da diabete mellito di tipo 1 idiopatico rispetto alla forma autoimmune in pazienti caucasici. Proceedings Vai
2018 Superior mesenteric artery syndrome: Clinical, endoscopic, and radiological findings Articolo in rivista Vai
2017 NANOG plays a hierarchical role in the transcription network regulating the pluripotency and plasticity of adipose tissue-derived stem cells Articolo in rivista Vai
2017 More favorable metabolic impact of three-times-weekly versus daily growth hormone (GH) treatment in naïve GH-deficient children Articolo in rivista Vai
2017 NEW THERAPEUTIC PERSPECTIVES IN IRRITABLE BOWEL SYNDROME: TARGETING LOW-GRADE INFLAMMATION, IMMUNO-NEUROENDOCRINE AXIS, MOTILITY, SDECRETION AND BEYOND Review essay (rassegna critica) Vai
2017 EFFECTS OF PASIREOTIDE TREATMENT ON CARDIOMETABOLIC RISK IN PATIENTS WITH CUSHING’S DISEASE : AN ITALIAN, MULTICENTER STUDY Proceedings Vai
2017 Comparison of clinical and metabolic effects of pasireotide and pituitary surgery in Cushing disease Proceedings Vai
2017 The degree of urinary hypercortisolism is not correlated with the severity of cushing’s syndrome Articolo in rivista Vai
2017 COLORECTAL CANCER IN PATIENTS WITH TYPE 2 DIABETES MELLITUS: A SINGLE-CENTRE EXPERIENCE. Articolo in rivista Vai
2017 Correlation between adrenal function, growth hormone secretion, and insulin sensitivity in children with idiopathic growth hormone deficiency Articolo in rivista Vai
2017 The Daily Consumption of Cola Can Determine Hypocalcemia: A Case Report of Postsurgical Hypoparathyroidism-Related Hypocalcemia Refractory to Supplemental Therapy with High Doses of Oral Calcium Articolo in rivista Vai
2017 Circulating adipokine levels in diabetic patients with Cushing disease on pasireotide treatment compared with patients with type 2 diabetes mellitus Proceedings Vai
2017 Clinical and metabolic impact of three-times-weekly versus daily growth hormone (GH) treatment in naïve GH-deficient children Proceedings Vai
2017 The visceral adiposity index is associated with insulin sensitivity and IGF-I levels in adults with growth hormone deficiency Articolo in rivista Vai
2016 Efficacy and safety of everolimus in extrapancreatic neuroendocrine tumor: A comprehensive review of literature Articolo in rivista Vai
2016 Resistin, visfatin, leptin and omentin are differently related to hormonal and metabolic parameters in growth hormone-deficient children Articolo in rivista Vai
2016 Miglioramento dell'insulino-sensibilità e dell'insulino-secrezione dopo switch da terapia con glucocorticoidi tradizionali a idrocortisone "dual release" in pazienti affetti da iposurrenalismo Proceedings Vai
2016 Modificazioni di insulino-secrezione, insulino-sensibilità e funzione adiposa durante terapia con pasireotide in un gruppo di pazienti con malattia di Cushing Proceedings Vai
2016 The treatment of hyperinsulinemic hypoglycaemia in adults: an update Articolo in rivista Vai
2015 Revaluation of the clinical and metabolic behavior of GHD children during GH treatment according to newly proposed note 39 of the Italian Medicines Agency (AIFA) Proceedings Vai
2015 IS THE DEGREE OF URINARY FREE CORTISOL AN EXHAUSTIVE PARAMETER FOR DEFINING CUSHING SYNDROME SEVERITY? Proceedings Vai
2015 INSULIN SECRETION AND SENSITIVITY DURING PASIREOTIDE TREATMENT IN PATIENTS WITH RECURRENT CUSHING DISEASE: A CASE SERIES Proceedings Vai
2014 Valutazione dell’insulino-sensibilità e della funzione adiposa viscerale nel diabete mellito tipo 1 autoimmune ed idiopatico. Proceedings Vai
2014 No phenotypic differences for polycystic ovary syndrome (PCOS) between women with and without type 1 diabetes mellitus. Articolo in rivista Vai
2014 IL CONSUMO DI BEVANDE RICCHE DI ACIDO ORTOFOSFORICO COME FATTORE DI RISCHIO PER LO SVILUPPO DI IPOCALCEMIA: IL CASO DI UNA DONNA CON IPOPARATIROIDISMO POST-CHIRURGICO Proceedings Vai
2014 Is diabetes in Cushing's syndrome only a consequence of hypercortisolism? Articolo in rivista Vai
2014 EFFECT OF SWITCH FROM CONVENTIONAL GLUCOCORTICOIDS TO “DUAL RELEASE HYDROCORTISONE” (DR-HC) ON METABOLIC PROFILE AND QUALITY OF LIFE IN ADULT PATIENTS WITH SECONDARY ADRENAL INSUFFICIENCY (SAI): RESULTS OF THREE MONTHS FOLLOW-UP Proceedings Vai
2014 Correlation between Severity of Growth Hormone Deficiency and Thyroid Metabolism and Effects of Long-Term Growth Hormone Treatment on Thyroid Function in Children with Idiopathic Growth Hormone Deficiency. Articolo in rivista Vai
2014 IPOVITAMINOSI D ED EFFETTI BENEFICI DELLA TERAPIA SOSTITUTIVA CON GH SUI LIVELLI DI VITAMINA D IN BAMBINI AFFETTI DA DEFICIT DI GH Proceedings Vai
2013 Body composition assessment for the definition of cardiometabolic risk. Articolo in rivista Vai
2013 Higher doses of cabergoline further improve metabolic parameters in patients with prolactinoma regardless of the degree of reduction in prolactin levels. Articolo in rivista Vai
2013 Maggior rischio cardiometabolico nelle donne affette da Cushing, anche in assenza di una franca Sindrome Metabolica. Proceedings Vai
2013 LONG-TERM METABOLIC EFFECTS OF GH THERAPY IN CHILDREN WITH IDIOPATHIC GH DEFICIENCY Proceedings Vai
2013 Alte dosi di cabergolina migliorano i parametri metabolici in pazienti affetti da prolattinoma. Proceedings Vai
2013 The adipose visceral dysfunction plays an important role in diabetes in Cushing disease. Proceedings Vai
2013 Poor diagnostic value of the euglycemic-hyperinsulinemic clamp in the clinical assessment of insulin resistant women with PCOS. Proceedings Vai
2013 Metabolically healthy polycystic ovary syndrome (MH-PCOS) and metabolically unhealthy polycystic ovary syndrome (MU-PCOS): a comparative analysis of four simple methods useful for metabolic assessment. Articolo in rivista Vai
2012 Visceral adiposity index is associated with insulin sensitivity and adipocytokine levels in newly diagnosed acromegalic patients. Proceedings Vai
2012 Janus kinase (JAK) 2 V617F mutation as the cause of primary thrombocythemia in acromegaly with severe visceromegaly and divergence between growth hormone and insulin-like growth factor-1 concentrations during the follow-up: causal or casual association? Articolo in rivista Vai
2012 Alta prevalenza di Sindrome dell’ovaio policistico in donne diabetiche di tipo 1 in età fertile. Proceedings Vai
2012 Thyroid function during long-term GH treatment in children affected by idiopathic GH deficiency Proceedings Vai
2012 Utilizzo del Visceral Adiposity Index per l’identificazione di donne con sindrome iperandrogenica a rischio cardiometabolico. Proceedings Vai
2012 Traitement séquential avec des corticostéroides dans les ophtalmopathy Graves Proceedings Vai
2012 Off-line control of the postprandial glycemia in type 1 diabetes patients by a fuzzy logic decision support Articolo in rivista Vai
2011 Development of a fuzzy expert system for the control of glycemia in type 1 diabetic patients Proceedings Vai
2011 Predictors of microvascular complications in type 1 diabetic patients at onset: The role of metabolic memory Articolo in rivista Vai
2011 GH-treatment improves growth and reduces the severity of fibrosis and hypertansaminasemia in a prepubertal child with sclerosant cholangiopathy Proceedings Vai
2011 Janus kinase (JAK) 2 V617F mutation as the cause of primary thrombocythemia, severe visceromegaly and divergence between growth hormone and insulin-like growth factor-1 concentrations in acromegaly due to a therapeutically resistant pituitary GH-secreting macroadenoma Proceedings Vai
2011 Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal-Dystrophy (APECED) in Sicily: confirmation that R203X is the peculiar AIRE gene mutation. Articolo in rivista Vai
2011 Insulin sensitivity and visceral adiposity index (VAI) in women with functional secondary amenorrhea. Proceedings Vai
2010 Sviluppo di un sistema di supporto decisionale tipo Fuzzy per il controllo della glicemia post-prandiale nel diabete mellito tipo 1 Proceedings Vai
2010 Efficacy and safety of long-term ezetimibe/simvastatin treatment in patients with familial hypercholesterolemia Articolo in rivista Vai
2009 Impact of atorvastatin plus n-3 PUFA on metabolic, inflammatory and coagulative parameters in metabolic syndrome without and with type 2 diabetes mellitus Articolo in rivista Vai
2008 Effetti a lungo termine del trattamento con Simvastatina ed Ezetimibe sui livelli di HDL-C e hs-PCR in pazienti affetti da Ipercolesterolemia familare(FH) con pregresso IMA e/o Lesione carotidea Proceedings Vai
2008 Relationship between body fat distribution and blood disorders in patients with visceral obesity with and without diabetes mellitus Articolo in rivista Vai
2008 Efficacia della associazione Atorvastatina e n-3 PUFA in pazienti affetti da dislipidemia combinata e ad alto rischio di eventi cardiovascolari Proceedings Vai