| 2024 |
Evaluation of the anticancer effects exerted by 5-fluorouracil and heme oxygenase-1 inhibitor hybrids in HTC116 colorectal cancer cells |
Articolo in rivista |
Vai |
| 2024 |
The Antitumor Potential of Sicilian Grape Pomace Extract: A Balance between ROS-Mediated Autophagy and Apoptosis |
Articolo in rivista |
Vai |
| 2023 |
A Deadly Liaison between Oxidative Injury and p53 Drives Methyl-Gallate-Induced Autophagy and Apoptosis in HCT116 Colon Cancer Cells |
Articolo in rivista |
Vai |
| 2023 |
Effetti benefici degli oli essenziali nel trattamento anti-obesità |
Review essay (rassegna critica) |
Vai |
| 2023 |
MCL1 Inhibition Overcomes the Aggressiveness Features of Triple-Negative Breast Cancer MDA-MB-231 Cells |
Articolo in rivista |
Vai |
| 2023 |
Discovery of SI 1/20 and SI 1/22 as Mutual Prodrugs of 5-Fluorouracil and Imidazole-Based Heme Oxygenase 1 Inhibitor with Improved Cytotoxicity in DU145 Prostate Cancer Cells |
Articolo in rivista |
Vai |
| 2023 |
Foodomics-Based Approaches Shed Light on the Potential Protective Effects of Polyphenols in Inflammatory
Bowel Disease |
Review essay (rassegna critica) |
Vai |
| 2023 |
Hypertrophy and ER Stress Induced by Palmitate Are Counteracted by Mango Peel and Seed Extracts in 3T3-L1 Adipocytes |
Articolo in rivista |
Vai |
| 2023 |
Oncogenic BRAF and p53 Interplay in Melanoma Cells and the Effects of the HDAC Inhibitor ITF2357 (Givinostat) |
Articolo in rivista |
Vai |
| 2023 |
Cytotoxic Effect Induced by Sicilian Oregano Essential Oil in Human Breast Cancer Cells |
Articolo in rivista |
Vai |
| 2022 |
Effetti benefici degli oli essenziali nel trattamento anti-obesità |
Abstract in atti di convegno pubblicato in rivista |
Vai |
| 2022 |
Bio-Waste Products of Mangifera indica L. Reduce Adipogenesis and Exert Antioxidant Effects on 3T3-L1 Cells |
Articolo in rivista |
Vai |
| 2022 |
The Histone Deacetylase Inhibitor ITF2357 (Givinostat) Targets Oncogenic BRAF in Melanoma Cells and Promotes a Switch from Pro-Survival Autophagy to Apoptosis |
Articolo in rivista |
Vai |
| 2022 |
Bortezomib potentiates the antitumor effect of tributyltin(IV) ferulate in colon cancer cells exacerbating ER stress and promoting apoptosis |
Articolo in rivista |
Vai |
| 2022 |
Parthenolide and Its Soluble Analogues: Multitasking Compounds with Antitumor Properties |
Review essay (rassegna critica) |
Vai |
| 2022 |
Organotin(IV) complexes with epigenetic modulator ligands: New promising candidates in cancer therapy |
Articolo in rivista |
Vai |
| 2021 |
SICILIAN MANGO PEEL INDUCES CELLULAR STRESS ACCOMPANIED TO MITOCHONDRIAL DYSFUNCTION IN COLON CANCER CELLS |
Abstract in atti di convegno pubblicato in rivista |
Vai |
| 2021 |
Tributyltin(Iv) butyrate: A novel epigenetic modifier with er stress-and apoptosis-inducing properties in colon cancer cells |
Articolo in rivista |
Vai |
| 2021 |
The good and bad of nrf2: An update in cancer and new perspectives in COVID-19 |
Review essay (rassegna critica) |
Vai |
| 2021 |
Oxidative stress induced by the novel compound tributyltin(iv) ferulate promotes ER stress and autophagy in colon cancer cells |
Abstract in atti di convegno pubblicato in rivista |
Vai |
| 2021 |
The beneficial effects of essential oils in anti-obesity treatment |
Review essay (rassegna critica) |
Vai |
| 2021 |
Oncogenic BRAF protein as a molecular target of HDAC inhibitors in melanoma cells |
Abstract in atti di convegno pubblicato in rivista |
Vai |
| 2021 |
Redox Imbalance and Mitochondrial Release of Apoptogenic Factors at the Forefront of the Antitumor Action of Mango Peel Extract |
Articolo in rivista |
Vai |
| 2020 |
Tributyltin(IV) ferulate, a novel synthetic ferulic acid derivative, induces autophagic cell death in colon cancer cells: From chemical synthesis to biochemical effects |
Articolo in rivista |
Vai |
| 2020 |
P62: Friend or foe? Evidences for oncojanus and neurojanus roles |
Review essay (rassegna critica) |
Vai |
| 2020 |
Dual function molecules and processes in cell fate decision: A preface to the special issue |
Lettera |
Vai |
| 2020 |
Gluten Free Diet for the Management of Non Celiac Diseases: The Two Sides of the Coin |
Articolo in rivista |
Vai |
| 2020 |
ROS-Dependent ER Stress and Autophagy Mediate the Anti-Tumor Effects of Tributyltin (IV) Ferulate in Colon Cancer Cells |
Articolo in rivista |
Vai |
| 2020 |
Brain Opioid Activity and Oxidative Injury: Different Molecular Scenarios Connecting Celiac Disease and Autistic Spectrum Disorder |
Articolo in rivista |
Vai |
| 2019 |
Ethanol-mediated stress promotes autophagic survival and aggressiveness of colon cancer cells via activation of Nrf2/HO-1 pathway |
Articolo in rivista |
Vai |
| 2019 |
WIN55,212-2-induced expression of Mir-29b1 favours the suppression of osteosarcoma cell migration in a SPARC-independent manner |
Articolo in rivista |
Vai |
| 2019 |
The Anti-Cancer Effect of Mangifera indica L. Peel Extract is Associated to γH2AX-mediated Apoptosis in Colon Cancer Cells |
Articolo in rivista |
Vai |
| 2018 |
The Double-Edged Sword Profile of Redox Signaling: Oxidative Events As Molecular Switches in the Balance between Cell Physiology and Cancer |
Review essay (rassegna critica) |
Vai |
| 2018 |
Sicilian litchi fruit extracts induce autophagy versus apoptosis switch in human colon cancer cells |
Articolo in rivista |
Vai |
| 2018 |
Ethanol promotes survival and tumor progression of colon cancer cells |
Contributo in atti di convegno pubblicato in volume |
Vai |
| 2018 |
Routes to cell death in animal and plant kingdoms: from classic apoptosis to alternative ways to die—a review |
Articolo in rivista |
Vai |
| 2018 |
Let-7d-5p miRNA shows oncogenic functions in triple negative breast cancer |
Abstract in atti di convegno pubblicato in volume |
Vai |
| 2017 |
Multifaceted Health Benefits of Mangifera indica L. (Mango): The Inestimable Value of Orchards Recently Planted in Sicilian Rural Areas |
Review essay (rassegna critica) |
Vai |
| 2017 |
Litchi chinensis as a Functional Food and a Source of Antitumor Compounds: An Overview and a Description of Biochemical Pathways |
Review essay (rassegna critica) |
Vai |
| 2016 |
The analysis of estrogen receptor-α positive breast cancer stem-like cells unveils a high expression of the serpin proteinase inhibitor PI-9: Possible regulatory mechanisms |
Articolo in rivista |
Vai |
| 2016 |
Autophagic cell death induced by Litchi fruit extracts in human colon cancer cells |
Abstract in atti di convegno pubblicato in volume |
Vai |
| 2016 |
DNA-Binding and Anticancer Activity of Pyrene-Imidazolium Derivatives |
Articolo in rivista |
Vai |
| 2016 |
The secreted protein acidic and rich in cysteine is a critical mediator of cell death program induced by WIN/TRAIL combined treatment in osteosarcoma cells |
Articolo in rivista |
Vai |
| 2015 |
Different modulatory effect of the synthetic cannabinoid WIN55,212-2 on tumor cell migration. |
Proceedings |
Vai |
| 2015 |
WIN-induced vesiculation cooperates to the inhibition of osteosarcoma cell migration |
Proceedings |
Vai |
| 2015 |
Il sostegno e il miglioramento delle coltivazioni sub-tropicali in Sicilia traggono vantaggio dallo studio e dalla promozione delle loro proprietà nutrizionali. |
Contributo in atti di convegno pubblicato in volume |
Vai |
| 2015 |
ER+-derived breast cancer stem cells reveal a high expression of the serpin protease inhibitor PI-9. |
Proceedings |
Vai |
| 2015 |
Possible regulatory mechanisms responsible for the high expression of serpin protease inhibitor PI-9 in ER+ -derived breast cancer stem cells. |
Proceedings |
Vai |
| 2014 |
Role of sparc and MIR-29B1 in molecular effects induced by win in
osteosarcoma MG63 cells |
Proceedings |
Vai |
| 2014 |
WIN modulates osteosarcoma MG63 cell migration by inhibiting MMPs activity and
adjusting intra- and extra-cellular SPARC differential expression |
Proceedings |
Vai |
| 2014 |
MicroRNA-29b-1 impairs in vitro cell proliferation, self‑renewal and chemoresistance of human osteosarcoma 3AB-OS cancer stem cells |
Articolo in rivista |
Vai |
| 2014 |
WIN induces apoptotic cell death in
human colon cancer cells through a block
of autophagic flux dependent on PPARγ
down-regulation |
Articolo in rivista |
Vai |
| 2014 |
Involvement of PAR-4 in Cannabinoid-Dependent Sensitization of Osteosarcoma Cells to TRAIL-Induced Apoptosis |
Articolo in rivista |
Vai |
| 2014 |
Mutant p53 gain of function can be at the root of dedifferentiation of human osteosarcoma MG63 cells into 3AB-OS cancer stem cells. |
Articolo in rivista |
Vai |
| 2013 |
Studio dell'autofagia nella citotossicità indotta dai cannabinoidi in cellule tumorali |
Proceedings |
Vai |
| 2013 |
Okadaic acid-Parthenolide combination at subtoxic doses induces potent synergistic apoptotic effects in human retinoblastoma Y79 cells by upregulating PTEN. |
Proceedings |
Vai |
| 2013 |
Genetic and molecular characterization of the human osteosarcoma 3AB-OS cancer stem cell line: a possible model for studying osteosarcoma origin and stemness. |
Articolo in rivista |
Vai |
| 2013 |
Synthesis, chemical characterization and biological activity of new
histone acetylation/deacetylation specific inhibitors: A novel and
potential approach to cancer therapy. |
Articolo in rivista |
Vai |
| 2013 |
In human retinoblastoma Y79 cells okadaic acid–parthenolide co-treatment induces synergistic apoptotic effects, with PTEN as a key player. |
Articolo in rivista |
Vai |
| 2013 |
Notch inhibition restores TRAIL-mediated apoptosis via AP1-dependent upregulation of DR4 and DR5 TRAIL receptors in MDA-MB-231 breast cancer cells. |
Articolo in rivista |
Vai |
| 2012 |
Different expression of PPARs in WIN-treated cells: the game of roles |
Proceedings |
Vai |
| 2012 |
Autophagy and ER-stress participate to cannabinoid-induced apoptosis in colon carcinoma cells |
Proceedings |
Vai |
| 2012 |
A comparison between the role of SPARC in osteogenic differentiation of mesenchymal stem cells and in WIN/TRAIL-induced apoptosis in osteosarcoma cells |
Proceedings |
Vai |
| 2012 |
Stromal SPARC contributes to the
detrimental fibrotic changes associated with myeloproliferation whereas its
deficiency favors myeloid cell expansion. |
Articolo in rivista |
Vai |
| 2012 |
INVOLVEMENT OF ER-STRESS IN SPARC UP-REGULATION INDUCED BY WIN AND IN APOPTOSIS OF MG63 CELLS |
Proceedings |
Vai |
| 2012 |
Cannabinoid-associated cell death mechanisms in tumor models (review) |
Articolo in rivista |
Vai |
| 2012 |
Organotin(IV) and simple fatty acids: preliminary assessments |
Proceedings |
Vai |
| 2011 |
New histone acetylation/deacetylation specific inhibitors: a novel and potential approach to cancer therapy |
Proceedings |
Vai |
| 2010 |
p8 (candidate of metasiasis 1) drives ER-stress/autophagy/apoptosis axis induced by the synthetic cannabinoid WIN in HCC cells. |
Proceedings |
Vai |
| 2010 |
Diorganotin(IV) N-acetyl-L-cysteinate complexes: Synthesis, solid state, solution phase, DFT and biological investigations. |
Articolo in rivista |
Vai |
| 2010 |
USO TERAPEUTICO COMBINATO DI ORGANOSTAGNO(IV) ED INIBITORI DELLE DEACETILASI ISTONICHE |
Brevetto |
Vai |
| 2010 |
Bu2Sn(N-acetyl-L-cysteinate) antitumor activity on HepG2 cells |
Proceedings |
Vai |
| 2010 |
Paclitaxel and beta-lapachone synergistically induce apoptosis in human retinoblastoma Y79 cells by downregulating the levels of phospho-Akt. |
Articolo in rivista |
Vai |
| 2010 |
The synthetic cannabinoid WIN sensitizes hepatocellular carcinoma cells to TRAIL-induced apoptosis by activating p8/CHOP/DR5 axis. |
Articolo in rivista |
Vai |
| 2009 |
The cannabinoid WIN induces DR5 receptor expression in hepatoma cells sensitizing them to TRAIL signal |
Proceedings |
Vai |
| 2009 |
COINVOLGIMENTO DELLO STRESS DEL RETICOLO E DEL PROCESSO AUTOFAGICO NELL’APOPTOSI INDOTTA DAL CANNABINOIDE SINTETICO WIN IN CELLULE DI EPATOMA UMANO IN COLTURA |
Proceedings |
Vai |
| 2009 |
Apoptosis induced in HepG2 cells by the synthetic cannabinoid WIN: involvement of the transcription factor PPARgamma. |
Articolo in rivista |
Vai |
| 2009 |
Identification and expansion of human osteosarcoma-cancer-stem cells by long-term 3-aminobenzamide treatment. |
Articolo in rivista |
Vai |
| 2009 |
The transcription factor CHOP is critical for WIN-mediated DR5 up-regulation in apoptosis induced by WIN/TRAIL co-treatment in hepatoma cells |
Proceedings |
Vai |
| 2008 |
The role of oxidative stress in apoptosis induced by the histone deacetylase inhibitor suberoylanilide hydroxamic acid in human colon adenocarcinoma HT-29 cells. |
Articolo in rivista |
Vai |
| 2008 |
TWO-DIMENSIONAL ANALYSIS OF PROTEIN EXPRESSION PATTERNS |
Monografia |
Vai |
| 2008 |
The synthetic cannabinoid WIN55,212-2 synergizes with the death receptor ligand TRAIL to induce apoptotic effect in HepG2 hepatoma cells. |
Proceedings |
Vai |
| 2008 |
ORGANOSTAGNO(IV) COMPLESSI CON
N-ACETILCISTEINA AD ATTIVITÀ ANTITUMORALE,
PROCEDIMENTO PER LA LORO PRODUZIONE E LORO
USO. |
Brevetto |
Vai |
| 2008 |
Low doses of paclitaxel potently induce apoptosis in human retinoblastoma Y79 cells by up-regulating E2F1. |
Articolo in rivista |
Vai |
| 2008 |
Synergistic effects induced by combinations of the synthetic cannabinoid WIN55,212-2 and the death receptor ligand TRAIL in hepatoma HepG2 cells. |
Proceedings |
Vai |
| 2008 |
CELL CULTURES |
Monografia |
Vai |
| 2007 |
Hsp72 controls bortezomib-induced HepG2 cell death via interaction with pro-apoptotic factors. |
Articolo in rivista |
Vai |
| 2007 |
WIN55,212-2, a synthetic agonist of cannabinoid receptors, sensitizes tumor cells to TRAIL-induced apoptosis. |
Proceedings |
Vai |
| 2007 |
Role of PPARγ in apoptosis induced by cannabinoids in hepatoma HepG2 cells. |
Proceedings |
Vai |
| 2007 |
Poly(ADP-ribose) polymerase (PARP): The advantages of using PARP inhibitors to modulate its activity in pathological conditions and to kill cancer cells |
Monografia |
Vai |
| 2007 |
The cannabinoid system and its potential therapeutic applications in cancer. |
Monografia |
Vai |
| 2006 |
Apoptosis induced by the histone deacetylase inhibitor SAHA in human colon adenocarcinoma cell line HT29 |
Proceedings |
Vai |
| 2006 |
Anandamide-induced apoptosis in Chang liver cells involves ceramide and JNK/AP-1 pathway. |
Articolo in rivista |
Vai |
| 2006 |
Hsp-72 contrasta l'effetto apoptotico indotto dal bortezomib in cellule di epatoblastoma umano Hep-G2 |
Proceedings |
Vai |
| 2006 |
Bortezomib induces in HepG2 cells IkappaBalpha degradation mediated by caspase-8. |
Articolo in rivista |
Vai |
| 2006 |
Factors that protect HepG2 cells by anandamide-induced cell death |
Proceedings |
Vai |
| 2006 |
THE CANNABINOID AGONIST WIN55,212-2 INDUCES APOPTOSIS IN HUMAN HEPATOMA CELLS. |
Proceedings |
Vai |
| 2006 |
Complessi di nuova sintesi di derivati della cisteina con ioni metallici |
Proceedings |
Vai |
| 2006 |
Synthesis, structural investigation and biological activity of metal ions complexes of N-acetylcysteine and carbocysteine |
Proceedings |
Vai |
| 2006 |
Hsp72 and NF-κB protect human hepatoma HepG2 cells in the first phase of treatment with bortezomib |
Proceedings |
Vai |
| 2005 |
APOPTOTIC EFFECTS INDUCED BY ANANDAMIDE IN HEPATIC CELLS. |
Proceedings |
Vai |
| 2005 |
SYNERGISTIC APOPTOTIC INTERACTION BETWEEN THE HDAC INHIBITOR SAHA AND THE PROTEASOME INHIBITOR BORTEZOMIB IN HUMAN HEPATOMA CELLS. |
Proceedings |
Vai |
| 2004 |
The involvement of the c-Jun/JNK/AP-1 pathway and HSPs in apoptosis induced by the proteasome inhibitor PS-341 (Velcade) in human hepatoma cells. |
Proceedings |
Vai |
| 2004 |
Staurosporine-induced apoptosis in Chang liver cells is associated with down-regulation of Bcl-2 and Bcl-XL. |
Articolo in rivista |
Vai |
| 2004 |
Degradation of IkBalfa during apoptosis induced by proteasome inhibitors in hepatoma cells. |
Proceedings |
Vai |
| 2003 |
Apoptosis meets proteasome, an invaluable therapeutic target of anticancer drugs |
Articolo in rivista |
Vai |
| 2003 |
The effect of 3-aminobenzamide, inhibitor of poly(ADP-ribose) polymerase, on human osteosarcoma cells |
Articolo in rivista |
Vai |
| 2003 |
Macrophage-mediated clearance of cells undergoing caspase-3-independent death |
Articolo in rivista |
Vai |
| 2003 |
Induction of apoptosis in human osteosarcoma Saos-2 cells by the proteasome inhibitor MG132 and the protective effect of pRb |
Articolo in rivista |
Vai |
| 2002 |
Apoptosis induced in hepatoblastoma HepG2 cells by the proteasome inhibitor MG132 is associated with hydrogen peroxide production, expression of Bcl-Xs and activation of caspase-3 |
Articolo in rivista |
Vai |
| 2001 |
Sodium phenylbutyrate induces apoptosis in human retinoblastoma Y79 cells: The effect of combined treatment with the topoisomerase I-inhibitor topotecan |
Articolo in rivista |
Vai |
| 2001 |
pRb suppresses camptothecin-induced apoptosis in human osteosarcoma Saos-2 cells by inhibiting c-Jun N-terminal kinase. |
Articolo in rivista |
Vai |
| 2000 |
Synergistic cytotoxic interactions between sodium butyrate, MG132 and camptothecin in human retinoblastoma Y79 cells |
Articolo in rivista |
Vai |
| 2000 |
Induction of apoptosis by arachidonic acid in human retinoblastoma Y79 cells: involvement of oxidative stress |
Articolo in rivista |
Vai |
| 1999 |
The apoptotic effects and synergistic interaction of sodium butyrate and MG132 in human retinoblastoma Y79 cells |
Articolo in rivista |
Vai |
| 1998 |
Increased cyclin E level in retinoblastoma cells during programmed cell death |
Articolo in rivista |
Vai |
| 1998 |
Induction of programmed cell death in human retinoblastoma Y79 cells by C2-ceramide |
Articolo in rivista |
Vai |
| 1998 |
Induction of apoptosis in human retinoblastoma cells by topoisomerase inhibitors |
Articolo in rivista |
Vai |
| 1998 |
The apoptotic effects of cisplatin and carboplatin in retinoblastoma Y79 cells |
Articolo in rivista |
Vai |
| 1998 |
Apoptotic effects of different drugs on cultured retinoblastoma Y79 cells |
Articolo in rivista |
Vai |
| 1997 |
Differentiation of Y79 cells induced by prolonged exposure to insulin |
Articolo in rivista |
Vai |
| 1996 |
Role of insulin-like growth factors in autocrine growth of human retinoblastoma Y79 cells |
Articolo in rivista |
Vai |
| 1994 |
Insulin synthesis in chick embryo retinas during development |
Articolo in rivista |
Vai |
| 1994 |
High-performance liquid chromatographic method for the determination of insulin synthesis in biological systems |
Articolo in rivista |
Vai |
| 1994 |
Synthesis of insulin and its effects in Y79 human retinoblastoma cells |
Articolo in rivista |
Vai |
| 1992 |
Identification and synthesis of insulin in human retinoblastoma Y-79 cells |
Articolo in rivista |
Vai |
| 1992 |
Identification of insulin in chick embryo retina during development and its inhibitory effect on DNA synthesis |
Articolo in rivista |
Vai |
| 1992 |
A factor derived from chick embryo retina which inhibits DNA synthesis of retina itself |
Articolo in rivista |
Vai |
| 1990 |
Effects of dexamethasone on human synovial fibroblast-like cells, from osteoarthritic joints, in culture |
Articolo in rivista |
Vai |
| 1990 |
The effects of dexamethasone on human synovial fibroblast-like cells, from ostheoarthritic joints, in culture |
Articolo in rivista |
Vai |
| 1989 |
Inhibition of DNA synthesis in chick embryo retinas, in vitro, by a factor from fetal bovine serum |
Articolo in rivista |
Vai |
| 1988 |
Morphological and biochemical effects of glucocorticoids in chick embryo hepatocytes during development |
Articolo in rivista |
Vai |
| 1987 |
DNA content and thymidine incorporation during chick embryo retina development:hydrocortisone effect |
Articolo in rivista |
Vai |
| 1987 |
Ornithine decarboxylase activity during chick embryo retina development:hydrocortisone effect |
Articolo in rivista |
Vai |
| 1987 |
Influence of hydrocortisone on chick embryo retina development |
Articolo in rivista |
Vai |
| 1985 |
Inhibitory effect of hydrocortisone administered in ovo on thymidine kinase in chick embryo retina during development |
Articolo in rivista |
Vai |
| 1985 |
Growth-inhibitory response elicited by hydrocortisone in chick embryo hepatocytes |
Articolo in rivista |
Vai |
| 1985 |
Nucleoside phosphotransferase in animal tissues. Tissue distribution and kinetic properties |
Articolo in rivista |
Vai |
| 1984 |
The effects of glucocorticoids on thymidine kinase and nucleoside phosphotransferase during development of chicken embryo retina |
Articolo in rivista |
Vai |
| 1984 |
The inhibitory effect of D-glucosamine on thymidine kinase in chick embryo retinas and HeLa cells |
Articolo in rivista |
Vai |
| 1984 |
Nucleoside phosphotransferase in animal tissues |
Articolo in rivista |
Vai |
| 1984 |
The purification and properties of nucleoside phosphotransferase from mucosa of chicken intestine |
Articolo in rivista |
Vai |
| 1983 |
Purification of nucleoside phosphotransferase from mucosa of chicken intestine |
Articolo in rivista |
Vai |
| 1983 |
The effects of glucocorticoids on thymidine kinase and nucleoside phosphotransferase during development of chicken embryo retina |
Articolo in rivista |
Vai |
| 1983 |
Inhibitory effect of phosphate on nucleoside phosphotransferase from chicken intestinal mucosa |
Articolo in rivista |
Vai |
| 1983 |
Regulatory properties of nucleoside phosphotransferase from mucosa of chicken intestine |
Articolo in rivista |
Vai |
