Electrochemical synthesis of coenzymes Qn by oxidation of tetramethoxy precursors
- Authors: Sabatino, MA;Filardo, G;Galia, A; Scialdone, O
- Publication year: 2009
- Type: Articolo in rivista (Articolo in rivista)
- Key words: Electrosynthesis; Coenzymes Qn; Anodic oxidation; Ubiquinones
- OA Link: http://hdl.handle.net/10447/58312
Abstract
The electrochemical oxidation of tetramethoxy precursors (2) to coenzymes Q (n) (1) at a carbon anode was investigated both in a bench-scale batch electrochemical reactor and in a continuous recirculation reaction system equipped with a parallel-plate electrochemical divided cell. High faradic efficiency (> 60%) and excellent selectivity (> 90%) in coenzymes Q (n) were obtained in CH3CN or CH3CN/CH2Cl2 + 0.15 M Bu4NBF4 under potentiostatic or amperostatic alimentation.