| 2024 |
The Antitumor Potential of Sicilian Grape Pomace Extract: A Balance between ROS-Mediated Autophagy and Apoptosis |
Articolo in rivista |
Vai |
| 2023 |
Effetti benefici degli oli essenziali nel trattamento anti-obesità |
Review essay (rassegna critica) |
Vai |
| 2023 |
Foodomics-Based Approaches Shed Light on the Potential Protective Effects of Polyphenols in Inflammatory
Bowel Disease |
Review essay (rassegna critica) |
Vai |
| 2023 |
A Deadly Liaison between Oxidative Injury and p53 Drives Methyl-Gallate-Induced Autophagy and Apoptosis in HCT116 Colon Cancer Cells |
Articolo in rivista |
Vai |
| 2023 |
Cytotoxic Effect Induced by Sicilian Oregano Essential Oil in Human Breast Cancer Cells |
Articolo in rivista |
Vai |
| 2023 |
Long non-coding RNA H19 enhances the pro-apoptotic activity of ITF2357 (a histone deacetylase inhibitor) in colorectal cancer cells |
Articolo in rivista |
Vai |
| 2023 |
MCL1 Inhibition Overcomes the Aggressiveness Features of Triple-Negative Breast Cancer MDA-MB-231 Cells |
Articolo in rivista |
Vai |
| 2023 |
Oncogenic BRAF and p53 Interplay in Melanoma Cells and the Effects of the HDAC Inhibitor ITF2357 (Givinostat) |
Articolo in rivista |
Vai |
| 2023 |
Hypertrophy and ER Stress Induced by Palmitate Are Counteracted by Mango Peel and Seed Extracts in 3T3-L1 Adipocytes |
Articolo in rivista |
Vai |
| 2022 |
Bortezomib potentiates the antitumor effect of tributyltin(IV) ferulate in colon cancer cells exacerbating ER stress and promoting apoptosis |
Articolo in rivista |
Vai |
| 2022 |
Organotin(IV) complexes with epigenetic modulator ligands: New promising candidates in cancer therapy |
Articolo in rivista |
Vai |
| 2022 |
The Histone Deacetylase Inhibitor ITF2357 (Givinostat) Targets Oncogenic BRAF in Melanoma Cells and Promotes a Switch from Pro-Survival Autophagy to Apoptosis |
Articolo in rivista |
Vai |
| 2022 |
Parthenolide and Its Soluble Analogues: Multitasking Compounds with Antitumor Properties |
Review essay (rassegna critica) |
Vai |
| 2022 |
Effetti benefici degli oli essenziali nel trattamento anti-obesità |
Abstract in atti di convegno pubblicato in rivista |
Vai |
| 2022 |
Bio-Waste Products of Mangifera indica L. Reduce Adipogenesis and Exert Antioxidant Effects on 3T3-L1 Cells |
Articolo in rivista |
Vai |
| 2021 |
The good and bad of nrf2: An update in cancer and new perspectives in COVID-19 |
Review essay (rassegna critica) |
Vai |
| 2021 |
SICILIAN MANGO PEEL INDUCES CELLULAR STRESS ACCOMPANIED TO MITOCHONDRIAL DYSFUNCTION IN COLON CANCER CELLS |
Abstract in atti di convegno pubblicato in rivista |
Vai |
| 2021 |
Tributyltin(Iv) butyrate: A novel epigenetic modifier with er stress-and apoptosis-inducing properties in colon cancer cells |
Articolo in rivista |
Vai |
| 2021 |
Redox Imbalance and Mitochondrial Release of Apoptogenic Factors at the Forefront of the Antitumor Action of Mango Peel Extract |
Articolo in rivista |
Vai |
| 2021 |
The beneficial effects of essential oils in anti-obesity treatment |
Review essay (rassegna critica) |
Vai |
| 2021 |
Oncogenic BRAF protein as a molecular target of HDAC inhibitors in melanoma cells |
Abstract in atti di convegno pubblicato in rivista |
Vai |
| 2021 |
Oxidative stress induced by the novel compound tributyltin(iv) ferulate promotes ER stress and autophagy in colon cancer cells |
Abstract in atti di convegno pubblicato in rivista |
Vai |
| 2020 |
Dual function molecules and processes in cell fate decision: A preface to the special issue |
Lettera |
Vai |
| 2020 |
Brain Opioid Activity and Oxidative Injury: Different Molecular Scenarios Connecting Celiac Disease and Autistic Spectrum Disorder |
Articolo in rivista |
Vai |
| 2020 |
Tributyltin(IV) ferulate, a novel synthetic ferulic acid derivative, induces autophagic cell death in colon cancer cells: From chemical synthesis to biochemical effects |
Articolo in rivista |
Vai |
| 2020 |
P62: Friend or foe? Evidences for oncojanus and neurojanus roles |
Review essay (rassegna critica) |
Vai |
| 2020 |
Gluten Free Diet for the Management of Non Celiac Diseases: The Two Sides of the Coin |
Articolo in rivista |
Vai |
| 2020 |
ROS-Dependent ER Stress and Autophagy Mediate the Anti-Tumor Effects of Tributyltin (IV) Ferulate in Colon Cancer Cells |
Articolo in rivista |
Vai |
| 2019 |
The Anti-Cancer Effect of Mangifera indica L. Peel Extract is Associated to γH2AX-mediated Apoptosis in Colon Cancer Cells |
Articolo in rivista |
Vai |
| 2019 |
Ethanol-mediated stress promotes autophagic survival and aggressiveness of colon cancer cells via activation of Nrf2/HO-1 pathway |
Articolo in rivista |
Vai |
| 2019 |
WIN55,212-2-induced expression of Mir-29b1 favours the suppression of osteosarcoma cell migration in a SPARC-independent manner |
Articolo in rivista |
Vai |
| 2018 |
Routes to cell death in animal and plant kingdoms: from classic apoptosis to alternative ways to die—a review |
Articolo in rivista |
Vai |
| 2018 |
Sicilian litchi fruit extracts induce autophagy versus apoptosis switch in human colon cancer cells |
Articolo in rivista |
Vai |
| 2018 |
The Double-Edged Sword Profile of Redox Signaling: Oxidative Events As Molecular Switches in the Balance between Cell Physiology and Cancer |
Review essay (rassegna critica) |
Vai |
| 2018 |
Ethanol promotes survival and tumor progression of colon cancer cells |
Contributo in atti di convegno pubblicato in volume |
Vai |
| 2017 |
Multifaceted Health Benefits of Mangifera indica L. (Mango): The Inestimable Value of Orchards Recently Planted in Sicilian Rural Areas |
Review essay (rassegna critica) |
Vai |
| 2017 |
Litchi chinensis as a Functional Food and a Source of Antitumor Compounds: An Overview and a Description of Biochemical Pathways |
Review essay (rassegna critica) |
Vai |
| 2016 |
The histone deacetylase inhibitor ITF2357 targets oncogenic BRAF in human melanoma cells |
Proceedings |
Vai |
| 2016 |
The histone deacetylase inhibitor SAHA induces HSP60 nitration and its extracellular release by exosomal vesicles in human lung-derived carcinoma cells |
Articolo in rivista |
Vai |
| 2016 |
Autophagic cell death induced by Litchi fruit extracts in human colon cancer cells |
Abstract in atti di convegno pubblicato in volume |
Vai |
| 2015 |
The Synergistic Effect of SAHA and Parthenolide in MDA-MB231 Breast Cancer Cells |
Articolo in rivista |
Vai |
| 2014 |
The oxygen radicals involved in the toxicity induced by parthenolide in MDA-MB-231 cells |
Articolo in rivista |
Vai |
| 2014 |
Synergistic effect of the HDAC inhibitor SAHA and the sesquiterpene lactone parthenolide in triple negative breast cancer cells. |
Proceedings |
Vai |
| 2014 |
The synergistic effect exerted by the HDAC inhibitor SAHA and the sesquiterpene
lactone parthenolide on triple negative breast canc
er cells |
Proceedings |
Vai |
| 2014 |
Heat shock protein 60 (Hsp60) modulation by the Histon Deacetylase Inhibitor (HDAC-i) SAHA in mucoepidermoid tumor H292 cells |
Proceedings |
Vai |
| 2014 |
The HDAC inhibitor SAHA synergistically stimulates
the cytotoxic effect induced by Parthenolide in
MDA-MB231 cells |
Proceedings |
Vai |
| 2013 |
Parthenolide induces superoxide anion production by stimulating EGF receptor in MDA-MB-231 breast cancer cells. |
Articolo in rivista |
Vai |
| 2013 |
Parthenolide induces EGF receptor phosphorylation and superoxide anion production in MDA-MB231 breast cancer cells. |
Proceedings |
Vai |
| 2013 |
Il partenolide stimola la produzione di ROS e autofagia in cellule di carcinoma mammario MDA-MB231.Il suo analogo solubile DMAPT inibisce la crescita e le metastasi di xenotrapianti di tumori mammari. |
Proceedings |
Vai |
| 2013 |
Synergistic cytotoxic interaction of the HDAC inhibitor SAHA with the natural compound parthenolide in MDA-MB231 breast cancer cells. |
Proceedings |
Vai |
| 2013 |
Parthenolide induces caspase-independent and AIF-mediated cell death in human osteosarcoma and melanoma cells. |
Articolo in rivista |
Vai |
| 2013 |
Parthenolide generates reactive oxygen species and autophagy in MDA-MB231 cells. A soluble parthenolide analogue inhibits tumour growth and metastasis in a xenograft model of breast cancer. |
Articolo in rivista |
Vai |
| 2012 |
Parthenolide induces caspase-independent cell death mediated by AIF in osteosarcoma and melanoma cells. |
Proceedings |
Vai |
| 2012 |
Parthenolide induces caspase-independent cell death in osteosarcoma, melanoma and breast cancer cells through the induction of oxidative stress. |
Proceedings |
Vai |
| 2012 |
Evaluation of the in vitro and in vivo antineoplastic effects of
Parthenolide on MDA-MB231 breast cancer cells |
Proceedings |
Vai |
| 2012 |
Parthenolide induces caspase-independent and AIF mediated cell death in tumor cells |
Proceedings |
Vai |
| 2011 |
Parthenolide sensitizes hepatocellular carcinoma cells to TRAIL by inducing the expression of death receptors through inhibition of STAT3 activation. |
Articolo in rivista |
Vai |
| 2011 |
The mechanism of parthenolide-induced cell death in tumor cell lines. |
Proceedings |
Vai |
| 2010 |
Anti tumor action of the natural compound parthenolide |
Proceedings |
Vai |
| 2009 |
Il partenolide sensibilizza le cellule di epatocarcinoma all'apoptosi indotta da TRAIL |
Proceedings |
Vai |
| 2009 |
Parthenolide sensitizes human hepatocarcinoma cells to TRAIL-induced apoptosis |
Proceedings |
Vai |
| 2009 |
Composizioni farmaceutiche per il trattamento di tumori epatici |
Brevetto |
Vai |
| 2009 |
Synergistic interaction between
Parthenolide and TRAIL induces apoptosis
in human hepatocarcinoma cells. |
Proceedings |
Vai |
| 2009 |
The histone deacetylase inhibitor suberoylanilide hydroxamic acid sensitizes human hepatocellular carcinoma cells to TRAIL-induced apoptosis by TRAIL-DISC activation |
Articolo in rivista |
Vai |
| 2008 |
Tumor models: in vivo applications |
Capitolo o Saggio |
Vai |
| 2008 |
C-DNA Microarray Analysis |
Capitolo o Saggio |
Vai |
| 2008 |
The sensitization of HepG2 and HT29 cells to TRAIL-induced apoptosis by histone deacetylase inhibitors is mediated by down-regulation of AKT and NF-kB. |
Proceedings |
Vai |
| 2008 |
The mechanism by which histone deacetylase inhibitors sensitize hepatoma and colon cancer cells to TRAIL-induced apoptosis |
Proceedings |
Vai |
| 2008 |
Histone deacetylase inhibitors: apoptotic effects and clinical implications (Review). |
Articolo in rivista |
Vai |
| 2008 |
Histone deacetylase inhibitors induce in human hepatoma HepG2 cells acetylation of p53 and histones in correlation with apoptotic effects. |
Articolo in rivista |
Vai |
| 2008 |
HISTONE DEACETYLASE INHIBITORS SENSITIZE HEPATOMA CELLS TO TRAIL_INDUCED APOPTOSIS |
Proceedings |
Vai |
| 2007 |
SAHA induces apoptosis in hepatoma cells and synergistically interacts with the proteasome inhibitor Bortezomib. |
Articolo in rivista |
Vai |
| 2007 |
Novel Apoptotic drugs in targeting tumor cells |
Curatela |
Vai |
| 2007 |
Histone deacetylase inhibitors: Epigenetic drugs acting by pleiotropic apoptotic mechanism in tumor cells and highly potent in combination with other antitumor agents. |
Proceedings |
Vai |
| 2007 |
THE APOPTOTIC EFFECT INDUCED IN HepG2 CELLS BY INHIBITORS OF HISTONE DEACETYLASES IS CORRELATED WITH ACETYLATION OF p53 AND HISTONES. |
Proceedings |
Vai |
| 2007 |
Role of the acetylation of p53 and histones in SAHA-induced apoptosis in human hepatoma HepG2 cells. |
Proceedings |
Vai |
| 2007 |
Histone deacetylase inhibitors in cancer therapy: Biological and clinical implications. |
Monografia |
Vai |
| 2007 |
WIN55,212-2, a synthetic agonist of cannabinoid receptors, sensitizes tumor cells to TRAIL-induced apoptosis. |
Proceedings |
Vai |
| 2007 |
The proteasome inhibitor bortezomib in programmed cell death and cancer therapy |
Monografia |
Vai |
| 2006 |
New perspectives in tumor therapy: molecular aspects, 2006 |
Curatela |
Vai |
| 2006 |
Synergistic apoptotic effect in HepG2 cells between bortezomib and hystone deacetylase inhibitors |
Proceedings |
Vai |
| 2006 |
JNK and AP-1 mediate apoptosis induced by bortezomib in HepG2 cells via FasL/caspase-8 and mitochondria-dependent pathways |
Articolo in rivista |
Vai |
| 2006 |
“Acetilazione di p53 e degli istoni nell’apoptosi indotta dal SAHA in cellule di epatoma umano HepG2” |
Proceedings |
Vai |
| 2006 |
“Effects of histone deacetylase inhibitors in human hepatoma cells and synergistic apoptotic interaction with the proteasome inhibitor Bortezomib” |
Proceedings |
Vai |
| 2006 |
SAHA induces acetylation of p53 and histones in human hepatoma HepG2 cells |
Proceedings |
Vai |
| 2006 |
THE ROLE OF THE EXTRINSIC PATHWAY OF APOPTOSIS IN THE EFFECT INDUCED BY SAHA IN HUMAN HEPATOMA CELLS. |
Proceedings |
Vai |
| 2005 |
JNK AND AP-1 MEDIATE APOPTOSIS INDUCED BY BORTEZOMIB IN HEPATOMA HEPG2 CELLS. |
Proceedings |
Vai |
| 2005 |
SYNERGISTIC APOPTOTIC INTERACTION BETWEEN THE HDAC INHIBITOR SAHA AND THE PROTEASOME INHIBITOR BORTEZOMIB IN HUMAN HEPATOMA CELLS. |
Proceedings |
Vai |
| 2005 |
THE APOPTOTIC EFFECT EXERTED IN HUMAN HEPATOMA CELLS BY THE INHIBITOR OF HISTONE DEACETYLASE SAHA EITHER ALONE OR IN COMBINATION WITH BORTEZOMIB. |
Proceedings |
Vai |
| 2004 |
Sodium butyrate induces apoptosis in human hepatoma cells by a mitochondria/caspase pathway, associated with degradation of beta-catenin, pRb and Bcl-XL. |
Articolo in rivista |
Vai |
| 2004 |
Proteasome inhibitor Velcade induces apoptosis in hepatoma HepG2 cells stimulating both the extrinsic and the intrinsic apoptotic pathways. |
Proceedings |
Vai |
| 2004 |
The involvement of the c-Jun/JNK/AP-1 pathway and HSPs in apoptosis induced by the proteasome inhibitor PS-341 (Velcade) in human hepatoma cells. |
Proceedings |
Vai |
| 2003 |
The effect of 3-aminobenzamide, inhibitor of poly(ADP-ribose) polymerase, on human osteosarcoma cells |
Articolo in rivista |
Vai |
| 2003 |
Induction of apoptosis in human osteosarcoma Saos-2 cells by the proteasome inhibitor MG132 and the protective effect of pRb |
Articolo in rivista |
Vai |
| 2002 |
Apoptosis induced in hepatoblastoma HepG2 cells by the proteasome inhibitor MG132 is associated with hydrogen peroxide production, expression of Bcl-Xs and activation of caspase-3 |
Articolo in rivista |
Vai |
| 2001 |
pRb suppresses camptothecin-induced apoptosis in human osteosarcoma Saos-2 cells by inhibiting c-Jun N-terminal kinase. |
Articolo in rivista |
Vai |
| 2000 |
Synergistic cytotoxic interactions between sodium butyrate, MG132 and camptothecin in human retinoblastoma Y79 cells |
Articolo in rivista |
Vai |
| 1999 |
The apoptotic effects and synergistic interaction of sodium butyrate and MG132 in human retinoblastoma Y79 cells |
Articolo in rivista |
Vai |
| 1998 |
Apoptotic effects of different drugs on cultured retinoblastoma Y79 cells |
Articolo in rivista |
Vai |
| 1998 |
The apoptotic effects of cisplatin and carboplatin in retinoblastoma Y79 cells |
Articolo in rivista |
Vai |
| 1998 |
Increased cyclin E level in retinoblastoma cells during programmed cell death |
Articolo in rivista |
Vai |
