Research Area
Active Research fields
Proteins which bind mRNA (RBP) encoding H1.0 and H3.3 histone variants in developing rat brain;
Production and release of extracellular vesicles (EV) by normal and tumor brain cells;
Isolation of EVs from biological fluids in normal and pathological conditions ;
Events controlling formation and maintenance of the blood brain barrier (BBB ) in in vitro systems;
Preparation of three-dimensional cultures of brain cells on poly-lactate scaffolds
Research projects of the last 5 years
No national or international project.
Collaborations
Prof. Dr. Daniel Gygax
Hochschule für Life Sciences FHNW
Studiengangleiter MLS
Gründenstrasse 40
4132 Muttenz
Active research
The research group uses essentially the laboratories of the STEBICEF Department, which has laboratories for cultures of eukaryotic and prokaryotic cells, fluorescence microscopes, a confocal microscope, refrigerated centrifuges and ultracentrifuges, equipped with different types of rotors, sonicators , a laboratory equipped for the use of radioisotopes , micromanipulators, thermostatic baths, instruments for the amplification of nucleic acids , etc .
Services delivered under the right of third parties
In the last 5 years, the research group has been involved with searching cyplasin receptors on behalf of Cyplasin Biomedical Ltd (Prof. Petzelt). In general terms, the group has the know-how for applying biochemical and biomolecular methods.