| 2024 |
The Antitumor Potential of Sicilian Grape Pomace Extract: A Balance between ROS-Mediated Autophagy and Apoptosis |
Articolo in rivista |
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| 2024 |
MANGIFERA INDICA L. EXTRACTS: A SOURCE OF BIOACTIVE COMPOUNDS TO TARGET REDOX BALANCE CIRCUITS IN CANCER AND OBESITY MODELS |
Abstract in atti di convegno pubblicato in volume |
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| 2024 |
Cow’s Milk: A Benefit for Human Health? Omics Tools and Precision Nutrition for Lactose Intolerance Management |
Review essay (rassegna critica) |
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| 2023 |
Foodomics-Based Approaches Shed Light on the Potential Protective Effects of Polyphenols in Inflammatory
Bowel Disease |
Review essay (rassegna critica) |
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| 2023 |
A Deadly Liaison between Oxidative Injury and p53 Drives Methyl-Gallate-Induced Autophagy and Apoptosis in HCT116 Colon Cancer Cells |
Articolo in rivista |
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| 2023 |
Effetti benefici degli oli essenziali nel trattamento anti-obesità |
Review essay (rassegna critica) |
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| 2023 |
Oncogenic BRAF and p53 Interplay in Melanoma Cells and the Effects of the HDAC Inhibitor ITF2357 (Givinostat) |
Articolo in rivista |
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| 2023 |
Curcumin and Andrographolide Co-Administration Safely Prevent Steatosis Induction and ROS Production in HepG2 Cell Line |
Articolo in rivista |
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| 2023 |
Hypertrophy and ER Stress Induced by Palmitate Are Counteracted by Mango Peel and Seed Extracts in 3T3-L1 Adipocytes |
Articolo in rivista |
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| 2023 |
MCL1 Inhibition Overcomes the Aggressiveness Features of Triple-Negative Breast Cancer MDA-MB-231 Cells |
Articolo in rivista |
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| 2023 |
Red and golden tomato administration improves fat diet-induced hepatic steatosis in rats by modulating HNF4α, Lepr, and GK expression |
Articolo in rivista |
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| 2023 |
Cytotoxic Effect Induced by Sicilian Oregano Essential Oil in Human Breast Cancer Cells |
Articolo in rivista |
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| 2023 |
Biomarkers in Laryngeal Squamous Cell Carcinoma: The Literature Review |
Articolo in rivista |
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| 2022 |
Parthenolide and Its Soluble Analogues: Multitasking Compounds with Antitumor Properties |
Review essay (rassegna critica) |
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| 2022 |
The Histone Deacetylase Inhibitor ITF2357 (Givinostat) Targets Oncogenic BRAF in Melanoma Cells and Promotes a Switch from Pro-Survival Autophagy to Apoptosis |
Articolo in rivista |
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| 2022 |
Bio-Waste Products of Mangifera indica L. Reduce Adipogenesis and Exert Antioxidant Effects on 3T3-L1 Cells |
Articolo in rivista |
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| 2022 |
Effetti benefici degli oli essenziali nel trattamento anti-obesità |
Abstract in atti di convegno pubblicato in rivista |
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| 2021 |
Oxidative stress induced by the novel compound tributyltin(iv) ferulate promotes ER stress and autophagy in colon cancer cells |
Abstract in atti di convegno pubblicato in rivista |
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| 2021 |
Oncogenic BRAF protein as a molecular target of HDAC inhibitors in melanoma cells |
Abstract in atti di convegno pubblicato in rivista |
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| 2021 |
Redox Imbalance and Mitochondrial Release of Apoptogenic Factors at the Forefront of the Antitumor Action of Mango Peel Extract |
Articolo in rivista |
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| 2021 |
The beneficial effects of essential oils in anti-obesity treatment |
Review essay (rassegna critica) |
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| 2021 |
The good and bad of nrf2: An update in cancer and new perspectives in COVID-19 |
Review essay (rassegna critica) |
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| 2021 |
SICILIAN MANGO PEEL INDUCES CELLULAR STRESS ACCOMPANIED TO MITOCHONDRIAL DYSFUNCTION IN COLON CANCER CELLS |
Abstract in atti di convegno pubblicato in rivista |
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| 2020 |
Lipid chaperones and associated diseases: a group of chaperonopathies defining a new nosological entity with implications for medical research and practice |
Articolo in rivista |
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| 2020 |
Brain Opioid Activity and Oxidative Injury: Different Molecular Scenarios Connecting Celiac Disease and Autistic Spectrum Disorder |
Articolo in rivista |
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| 2020 |
Amminoacidi e proteine |
Capitolo o Saggio |
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| 2020 |
P62: Friend or foe? Evidences for oncojanus and neurojanus roles |
Review essay (rassegna critica) |
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| 2020 |
ROS-Dependent ER Stress and Autophagy Mediate the Anti-Tumor Effects of Tributyltin (IV) Ferulate in Colon Cancer Cells |
Articolo in rivista |
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| 2020 |
Gluten Free Diet for the Management of Non Celiac Diseases: The Two Sides of the Coin |
Articolo in rivista |
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| 2019 |
Extracellular vesicle-mediated cell–cell communication in the nervous system: Focus on neurological diseases |
Review essay (rassegna critica) |
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| 2019 |
Ethanol-mediated stress promotes autophagic survival and aggressiveness of colon cancer cells via activation of Nrf2/HO-1 pathway |
Articolo in rivista |
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| 2019 |
The Anti-Cancer Effect of Mangifera indica L. Peel Extract is Associated to γH2AX-mediated Apoptosis in Colon Cancer Cells |
Articolo in rivista |
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| 2018 |
Ethanol promotes survival and tumor progression of colon cancer cells |
Contributo in atti di convegno pubblicato in volume |
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| 2017 |
Parthenolide prevents resistance of MDA-MB231 cells to doxorubicin and mitoxantrone: the role of Nrf2 |
Articolo in rivista |
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| 2017 |
Suppressive role exerted by microRNA-29b-1-5p in triple negative breast cancer through SPIN1 regulation |
Articolo in rivista |
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| 2016 |
Let-7d miRNA Shows Both Antioncogenic and Oncogenic Functions in Osteosarcoma-Derived 3AB-OS Cancer Stem Cells |
Articolo in rivista |
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| 2016 |
The analysis of estrogen receptor-α positive breast cancer stem-like cells unveils a high expression of the serpin proteinase inhibitor PI-9: Possible regulatory mechanisms |
Articolo in rivista |
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| 2016 |
Parthenolide and DMAPT exert cytotoxic effects on breast cancer stem-like cells by inducing oxidative stress, mitochondrial dysfunction and necrosis |
Articolo in rivista |
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| 2016 |
Unusual roles of caspase-8 in triple-negative breast cancer cell line MDA-MB-231 |
Articolo in rivista |
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| 2015 |
Janus-Faced role of microRNA let-7d in osteosarcoma 3AB-OS cancer stem cells |
Abstract in atti di convegno pubblicato in volume |
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| 2015 |
The Synergistic Effect of SAHA and Parthenolide in MDA-MB231 Breast Cancer Cells |
Articolo in rivista |
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| 2015 |
Possible regulatory mechanisms responsible for the high expression of serpin protease inhibitor PI-9 in ER+ -derived breast cancer stem cells. |
Proceedings |
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| 2015 |
ER+-derived breast cancer stem cells reveal a high expression of the serpin protease inhibitor PI-9. |
Proceedings |
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| 2015 |
In human osteosarcoma 3AB-OS cancer stem cells let-7d seems to have the dual function of oncogene/tumor-suppressor miRNA |
Abstract in atti di convegno pubblicato in volume |
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| 2015 |
Non-canonical roles of caspase-8 in MDA-MB-231 breast cancer cell line |
Abstract in atti di convegno pubblicato in volume |
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| 2015 |
The cytotoxic effect exerted by parthenolide and DMAPT on breast cancer stem-like cells |
Abstract in atti di convegno pubblicato in volume |
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| 2014 |
Synthesis and antiproliferative activity of a natural like glucosyl polycyclic compound |
Proceedings |
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| 2014 |
The oxygen radicals involved in the toxicity induced by parthenolide in MDA-MB-231 cells |
Articolo in rivista |
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| 2014 |
Retinoblastoma: History of His Identification, Characterization and Treatment |
Articolo in rivista |
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| 2014 |
Synthesis and antiproliferative activity of new derivatives containing the polycyclic system 5,7:7,13-dimethanopyrazolo[3,4-b]pyrazolo[3’,4’:2,3]azepino[4,5-f]azocine |
Articolo in rivista |
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| 2014 |
The synergistic effect exerted by the HDAC inhibitor SAHA and the sesquiterpene
lactone parthenolide on triple negative breast canc
er cells |
Proceedings |
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| 2014 |
Synthesis and antirpoliferative activity of isoxazolo[3,4-d]pyridazin-7(6H)-one derivatives |
Proceedings |
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| 2014 |
Synergistic effect of the HDAC inhibitor SAHA and the sesquiterpene lactone parthenolide in triple negative breast cancer cells. |
Proceedings |
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| 2014 |
The HDAC inhibitor SAHA synergistically stimulates
the cytotoxic effect induced by Parthenolide in
MDA-MB231 cells |
Proceedings |
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| 2014 |
A short story of 3AB-OS cancer stem cells, a possible model
for studying cancer stemness |
Articolo in rivista |
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| 2014 |
Mutant p53 gain of function can be at the root of dedifferentiation of human osteosarcoma MG63 cells into 3AB-OS cancer stem cells. |
Articolo in rivista |
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| 2014 |
MicroRNA-29b-1 impairs in vitro cell proliferation, self‑renewal and chemoresistance of human osteosarcoma 3AB-OS cancer stem cells |
Articolo in rivista |
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| 2013 |
Parthenolide induces superoxide anion production by stimulating EGF receptor in MDA-MB-231 breast cancer cells. |
Articolo in rivista |
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| 2013 |
Parthenolide generates reactive oxygen species and autophagy in MDA-MB231 cells. A soluble parthenolide analogue inhibits tumour growth and metastasis in a xenograft model of breast cancer. |
Articolo in rivista |
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| 2013 |
In human retinoblastoma Y79 cells okadaic acid–parthenolide co-treatment induces synergistic apoptotic effects, with PTEN as a key player. |
Articolo in rivista |
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| 2013 |
Differentiation of human osteosarcoma 3AB-OS stem-like cells in derivatives of the three primary germ layers as an useful in vitro model to develop several purposes |
Articolo in rivista |
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| 2013 |
Parthenolide induces EGF receptor phosphorylation and superoxide anion production in MDA-MB231 breast cancer cells. |
Proceedings |
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| 2013 |
Synergistic cytotoxic interaction of the HDAC inhibitor SAHA with the natural compound parthenolide in MDA-MB231 breast cancer cells. |
Proceedings |
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| 2013 |
Parthenolide induces caspase-independent and AIF-mediated cell death in human osteosarcoma and melanoma cells. |
Articolo in rivista |
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| 2013 |
Il partenolide stimola la produzione di ROS e autofagia in cellule di carcinoma mammario MDA-MB231.Il suo analogo solubile DMAPT inibisce la crescita e le metastasi di xenotrapianti di tumori mammari. |
Proceedings |
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| 2013 |
Okadaic acid-Parthenolide combination at subtoxic doses induces potent synergistic apoptotic effects in human retinoblastoma Y79 cells by upregulating PTEN. |
Proceedings |
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| 2012 |
Evaluation of the in vitro and in vivo antineoplastic effects of
Parthenolide on MDA-MB231 breast cancer cells |
Proceedings |
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| 2012 |
Parthenolide induces caspase-independent and AIF mediated cell death in tumor cells |
Proceedings |
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| 2012 |
Modeling human osteosarcoma in mice through 3AB-OS cancer stem cell xenografts |
Articolo in rivista |
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| 2012 |
Parthenolide induces caspase-independent cell death in osteosarcoma, melanoma and breast cancer cells through the induction of oxidative stress. |
Proceedings |
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| 2012 |
Parthenolide induces caspase-independent cell death mediated by AIF in osteosarcoma and melanoma cells. |
Proceedings |
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| 2012 |
SAHA/TRAIL combination induces detachment and anoikis of MDA-MB231
and MCF-7 breast cancer cells |
Articolo in rivista |
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| 2012 |
Il partenolide induce morte in cellule di osteosarcoma umano MG63 mediante un meccanismi caspasi-indipendente, mediato da AIF. |
Proceedings |
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| 2011 |
Parthenolide sensitizes hepatocellular carcinoma cells to TRAIL by inducing the expression of death receptors through inhibition of STAT3 activation. |
Articolo in rivista |
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| 2011 |
The mechanism of parthenolide-induced cell death in tumor cell lines. |
Proceedings |
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| 2010 |
Anti tumor action of the natural compound parthenolide |
Proceedings |
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| 2009 |
Il partenolide sensibilizza le cellule di epatocarcinoma all'apoptosi indotta da TRAIL |
Proceedings |
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| 2009 |
The histone deacetylase inhibitor suberoylanilide hydroxamic acid sensitizes human hepatocellular carcinoma cells to TRAIL-induced apoptosis by TRAIL-DISC activation |
Articolo in rivista |
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| 2009 |
Parthenolide sensitizes human hepatocarcinoma cells to TRAIL-induced apoptosis |
Proceedings |
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| 2009 |
Synergistic interaction between
Parthenolide and TRAIL induces apoptosis
in human hepatocarcinoma cells. |
Proceedings |
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| 2008 |
Quaderni del Dottorato di Ricerca in Oncobiologia Sperimentale: Tecniche e Procedure di Ricerca |
Curatela |
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| 2008 |
Identification of Protein Complexes by Coimmunoprecipitation |
Capitolo o Saggio |
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| 2008 |
The mechanism by which histone deacetylase inhibitors sensitize hepatoma and colon cancer cells to TRAIL-induced apoptosis |
Proceedings |
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| 2008 |
C-DNA Microarray Analysis |
Capitolo o Saggio |
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| 2008 |
HISTONE DEACETYLASE INHIBITORS SENSITIZE HEPATOMA CELLS TO TRAIL_INDUCED APOPTOSIS |
Proceedings |
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| 2008 |
Histone deacetylase inhibitors induce in human hepatoma HepG2 cells acetylation of p53 and histones in correlation with apoptotic effects. |
Articolo in rivista |
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| 2008 |
The sensitization of HepG2 and HT29 cells to TRAIL-induced apoptosis by histone deacetylase inhibitors is mediated by down-regulation of AKT and NF-kB. |
Proceedings |
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| 2007 |
THE APOPTOTIC EFFECT INDUCED IN HepG2 CELLS BY INHIBITORS OF HISTONE DEACETYLASES IS CORRELATED WITH ACETYLATION OF p53 AND HISTONES. |
Proceedings |
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| 2007 |
SAHA induces apoptosis in hepatoma cells and synergistically interacts with the proteasome inhibitor Bortezomib. |
Articolo in rivista |
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| 2007 |
Histone deacetylase inhibitors: Epigenetic drugs acting by pleiotropic apoptotic mechanism in tumor cells and highly potent in combination with other antitumor agents. |
Proceedings |
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| 2007 |
Role of the acetylation of p53 and histones in SAHA-induced apoptosis in human hepatoma HepG2 cells. |
Proceedings |
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| 2006 |
JNK and AP-1 mediate apoptosis induced by bortezomib in HepG2 cells via FasL/caspase-8 and mitochondria-dependent pathways |
Articolo in rivista |
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| 2006 |
“Acetilazione di p53 e degli istoni nell’apoptosi indotta dal SAHA in cellule di epatoma umano HepG2” |
Proceedings |
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| 2006 |
THE ROLE OF THE EXTRINSIC PATHWAY OF APOPTOSIS IN THE EFFECT INDUCED BY SAHA IN HUMAN HEPATOMA CELLS. |
Proceedings |
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| 2006 |
Anandamide-induced apoptosis in Chang liver cells involves ceramide and JNK/AP-1 pathway. |
Articolo in rivista |
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| 2006 |
SAHA induces acetylation of p53 and histones in human hepatoma HepG2 cells |
Proceedings |
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| 2006 |
“Effects of histone deacetylase inhibitors in human hepatoma cells and synergistic apoptotic interaction with the proteasome inhibitor Bortezomib” |
Proceedings |
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| 2005 |
SYNERGISTIC APOPTOTIC INTERACTION BETWEEN THE HDAC INHIBITOR SAHA AND THE PROTEASOME INHIBITOR BORTEZOMIB IN HUMAN HEPATOMA CELLS. |
Proceedings |
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| 2005 |
JNK AND AP-1 MEDIATE APOPTOSIS INDUCED BY BORTEZOMIB IN HEPATOMA HEPG2 CELLS. |
Proceedings |
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| 2005 |
THE APOPTOTIC EFFECT EXERTED IN HUMAN HEPATOMA CELLS BY THE INHIBITOR OF HISTONE DEACETYLASE SAHA EITHER ALONE OR IN COMBINATION WITH BORTEZOMIB. |
Proceedings |
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| 2004 |
The involvement of the c-Jun/JNK/AP-1 pathway and HSPs in apoptosis induced by the proteasome inhibitor PS-341 (Velcade) in human hepatoma cells. |
Proceedings |
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| 2004 |
Proteasome inhibitor Velcade induces apoptosis in hepatoma HepG2 cells stimulating both the extrinsic and the intrinsic apoptotic pathways. |
Proceedings |
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