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MARIA GRAZIA ZIZZO

Role of cyclooxygenase pathways in bowel fibrotic remodelling in a murine model of experimental colitis

  • Authors: Colucci, Rocchina; Fornai, Matteo; Antonioli, Luca; Segnani, Cristina; Ippolito, Chiara; Pellegrini, Carolina; Nericcio, Anna; Zizzo, Maria Grazia; Serio, Rosa; Blandizzi, Corrado; Bernardini, Nunzia
  • Publication year: 2022
  • Type: Articolo in rivista
  • Key words: Cyclooxygenase; SMAD; TGF-β; fibrosis; inflammatory bowel disease
  • OA Link: http://hdl.handle.net/10447/576428

Abstract

Gut fibrosis occurs under chronic inflammation. This study examined the effects of different cyclooxygenase (COX) inhibitors on fibrosis in the inflamed colon.