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MARCO TUTONE

OXADIAZOLE DERIVATIVES FOR THE TREATMENT OF GENETIC DISEASES DUE TO NONSENSE MUTATIONS

  • Autori: Ivana Pibiri; Andrea Pace; Marco Tutone; Laura Lentini; Raffaella Melfi; Aldo Di Leonardo
  • Anno di pubblicazione: 2018
  • Tipologia: Brevetto
  • OA Link: http://hdl.handle.net/10447/391635

Abstract

Are disclosed oxadiazole derivatives, their use as medicaments and in particular for the treatment of diseases associated with the presence of a nonsense mutation in the gene or a premature stop codon in the mRNA, pharmaceutical formulation comprising said oxadiazole derivatives and prodrug or mixture thereof and the methods for the preparation of said Oxadiazole derivatives.