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GIUSEPPE SALEMI

Age at menopause predicts age at onset of Parkinson's disease.

  • Authors: RAGONESE P; D'AMELIO M; CALLARI G; SALEMI G; MORGANTE L; SAVETTIERI G
  • Publication year: 2006
  • Type: Articolo in rivista (Articolo in rivista)
  • OA Link: http://hdl.handle.net/10447/6145

Abstract

We investigated the association between age at onset of Parkinson's disease (PD) and fertile life characteristics in 145 women. Linear regression analyses showed a significant correlation between age at PD onset and age at menopause (P = 0.003), between age at PD onset and fertile life duration (P = 0.008), and a nonsignificant correlation between PD onset and cumulative duration of pregnancies (P = 0.23). These results support the possible role of estrogens in PD.