Triiodothyronine accelerates the synthesis of Synapsin I in developing neurons from fetal rat brain cultured in a synthetic medium
- Autori: Salemi, G.; Ferraro, D.; Savettieri, G.
- Anno di pubblicazione: 1990
- Tipologia: Articolo in rivista (Articolo in rivista)
- Parole Chiave: chemically defined medium; CNS development; immunofluorescence; neuronal culture; Synapsin 1; triiodothyronine; Neuroscience (all); Biochemistry
- OA Link: http://hdl.handle.net/10447/207496
Abstract
The effect of Triiodothyronine (T3) on Synapsin I appearance in rat cortical neurons has been investigated in vitro. Neuronal cultures from 16-day-old fetal rat brain grown in the absence of T3, express immunohystochemically detectable Synapsin I at the 14th day in vitro. The addition of the hormone to the culture medium determines an early (at the 7th day in vitro) appearance of fluorescent dots specific for Synapsin I. © 1990 Plenum Publishing Corporation.