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CINZIA SCIALABBA

Nanoreactors for the multi-functionalization of poly-histidine fragments

  • Authors: Paolino, Marco; Reale, Annalisa; Razzano, Vincenzo; Giuliani, Germano; Donati, Alessandro; Bonechi, Claudia; Caselli, Gianfranco; Visintin, Michela; Makovec, Francesco; Scialabba, Cinzia; Licciardi, Mariano; Paccagnini, Eugenio; Gentile, Mariangela; Salvini, Laura; Tavanti, Francesco; Menziani, Maria Cristina; Cappelli, Andrea
  • Publication year: 2019
  • Type: Articolo in rivista (Articolo in rivista)
  • OA Link: http://hdl.handle.net/10447/368730

Abstract

Water-soluble MBHA derivatives were found to self-assemble in a water environment to generate aggregates showing core–shell architectures. The aggregates appeared to be capable of working as nanoreactors performing a multi-functionalization of polyhistidine fragments, which after an initial interaction with the solvated oligo(ethylene glycol) shell reach the reactive core.