Nanoreactors for the multi-functionalization of poly-histidine fragments
- Autori: Paolino, Marco; Reale, Annalisa; Razzano, Vincenzo; Giuliani, Germano; Donati, Alessandro; Bonechi, Claudia; Caselli, Gianfranco; Visintin, Michela; Makovec, Francesco; Scialabba, Cinzia; Licciardi, Mariano; Paccagnini, Eugenio; Gentile, Mariangela; Salvini, Laura; Tavanti, Francesco; Menziani, Maria Cristina; Cappelli, Andrea
- Anno di pubblicazione: 2019
- Tipologia: Articolo in rivista (Articolo in rivista)
- OA Link: http://hdl.handle.net/10447/368730
Abstract
Water-soluble MBHA derivatives were found to self-assemble in a water environment to generate aggregates showing core–shell architectures. The aggregates appeared to be capable of working as nanoreactors performing a multi-functionalization of polyhistidine fragments, which after an initial interaction with the solvated oligo(ethylene glycol) shell reach the reactive core.