Monte Carlo analysis of polymer translocation with deterministic and noisy electric fields
- Authors: Valenti , D; Denaro, G; Persano Adorno, D; Pizzolato, N; Zammito, S; Spagnolo, B
- Publication year: 2012
- Type: Articolo in rivista (Articolo in rivista)
- Key words: polymer molecules; transport dynamics of biomolecules; noise in biological systems; Monte Carlo simulations
- OA Link: http://hdl.handle.net/10447/63397
Abstract
Polymer translocation through the nanochannel is studied by means of a Monte Carlo approach, in the presence of a static or oscillating external electric voltage. The polymer is described as a chain molecule according to the two-dimensional "bond fluctuation model". It moves through a piecewise linear channel, which mimics a nanopore in a biological membrane. The monomers of the chain interact with the walls of the channel, modelled as a reflecting barrier. We analyze the polymer dynamics, concentrating on the translocation time through the channel, when an external electric field is applied. By introducing a source of coloured noise, we analyze the effect of correlated random fluctuations on the polymer translocation dynamics.