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SIMONA RUBINO

Novel platinum(II) complexes with heterociclyc ligands: Synthesis and structural chracterization.

  • Autori: Rubino, S; Girasolo, MA; Stocco, GC
  • Anno di pubblicazione: 2008
  • Tipologia: Articolo in rivista (Breve introduzione)
  • Parole Chiave: mononuclear platinum complexes, heterocyclic ligands
  • OA Link: http://hdl.handle.net/10447/44171

Abstract

An array of mononuclear complexes of Pt(II) with triazine and (benzimidazolyl)pyridine heterocycles is reported. The mononuclear complexes [PtCl2(Kdptdn)] [dbtdn=5,6- diphenyl-3-(2-pyridyl)-1,2,4-triazine-4’,4’’-disulfonate sodium salt hydrate], [PtCl2(bbp)] [bbp=2,6-bis(2-benzimidazolyl)pyridine] and [PtCl2(H2dpt)]PtCl4 [dpt=5,6-diphenyl-3-(2- pyridyl)-1,2,4-triazine] have been prepared and structurally characterized. Both neutral and ionic complexes are present, with bifunctional Pt(II) moieties, whose size and shape enable them to behave as novel scaffolds for DNA binding.