Usefulness of the index of NASH - ION for the diagnosis of steatohepatitis in patients with non-alcoholic fatty liver: An external validation study
- Authors: Younes, R.; Rosso, C.; Petta, S.; Cucco, M.; Marietti, M.; Caviglia, G.; Ciancio, A.; Abate, M.; Cammà , C.; Smedile, A.; Craxi, A.; Saracco, G.; Bugianesi, E.
- Publication year: 2017
- Type: Articolo in rivista (Articolo in rivista)
- Key words: fibrosis; non-invasive marker; steatohepatitis
- OA Link: http://hdl.handle.net/10447/248099
Abstract
The non-invasive identification of steatohepatitis (NASH) in patients with Non-Alcoholic Fatty Liver Disease is an unmet need in clinical practice. Index of NASH (ION) is a new tool for the prediction of NASH. We aimed to externally validate ION and to compare it with CK-18. Since necroinflammation precedes fibrosis, we also tested ION in combination with non-invasive tools for fibrosis.