Towards bioarrays of cellular-like compartments for monitoring few molecular binding events
- Authors: Arrabito, G.; Cavaleri, F.; Montalbano, V.; Vetri, V.; Leone, M.; Pignataro, B.
- Publication year: 2016
- Type: Abstract in atti di convegno pubblicato in volume
- OA Link: http://hdl.handle.net/10447/227891
Abstract
The aim of this work is to artificially reproduce scalable cellular-like compartments on a chip, thus realizing specialized small volume systems to study the behaviour of interacting biomolecules by few binding events. In particular, we show an unprecedented solution-based protein-binding assay based on arrays of oil-confined water droplets containing protein targets, labelled ligands and other compounds.