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ANTONIO PALUMBO PICCIONELLO

Synthesis of oxazolidinones from N-aryl-carbamate and epichlorohydrin under mild conditions

  • Authors: Moreno L.M.; Marzullo P.; Buscemi S.; Insuasty B.; Palumbo Piccionello A.
  • Publication year: 2022
  • Type: Articolo in rivista
  • OA Link: http://hdl.handle.net/10447/549999

Abstract

The reaction conditions for an enantiospecific synthesis of various N-aryl-oxazolidinones from N-aryl-carbamates and (R) or (S) epichlorohydrin were optimized. The N-aryl-oxazolidinones were applied to the synthesis of compounds of biological interest such as DuP 721, toloxatone and a linezolid analogue.