Guaianolides from the aerial parts of Centaurea hololeuca
- Authors: ROSSELLI S; MAGGIO A; RACCUGLIA R A; SIMMONDS; M S J; ARNOLD N A; BRUNO M
- Publication year: 2006
- Type: Articolo in rivista (Articolo in rivista)
- OA Link: http://hdl.handle.net/10447/1866
Abstract
Seven guaianolides were isolated from the acetone extract of the aerial parts of Centaurea hololeuca Boiss. The antifeedant activity of the natural compounds (1-7) and of four chloro derivatives (8-11), synthesized from repin (1) and janerin (3) were tested against larvae of Spodoptera littoralis. Cebellin J (6) and chlorojanerin (11) showed significant antifeedant activity at 100 ppm, whereas at this concentration cebellin G (4) and 15-deschloro-15- hydroxychlorojanerin (7) stimulated feeding. Cebellin G (4) stimulated larvae of S. littoralis to feed at low concentration, but deterred feeding at high concentrations. The addition of chlorine to repin (1) resulted in an increase in antifeedant activity.