Gas-phase ion chemistry of protonated melatonin
- Authors: Bongiorno,D;Ceraulo,L;Camarda,L;Ciofalo,M; Ferrugia,M;Indelicato,S;Mele,A;Turco Liveri,V
- Publication year: 2009
- Type: Articolo in rivista (Articolo in rivista)
- Key words: melatonin, ESI/MS, ESI/MS/MS,ion chemistry
- OA Link: http://hdl.handle.net/10447/38855
Abstract
The gas-phase ion chemistry of protonated melatonin has been investigated by mass spectrometric (MS) techniques involving chemical ionisation, fast atom bombardment and electrospray ionisation. Either naturally- occurring or collision-induced decomposition N-D derivatives obtained by exchange with D(2)O. The analysis of experimental results allows definite pathways for the formation of the ion at m/z 174 to be assigned and sheds some more light on the overall fragmentation pathways. Experiments on labelled derivatives evidenced H-D scrambling processes during fragmentation.