Electrochemical oxidation of tetramethoxy precursor as a key step for the synthesis of coenzyme Q10
- Autori: Sabatino, MA; Galia, A; Filardo, G; Scialdone, O
- Anno di pubblicazione: 2007
- Tipologia: Articolo in rivista
- Parole Chiave: AnodesAnodic oxidationCarbonElectrooxidationPlatinumSynthesis (chemical)Water content
- OA Link: http://hdl.handle.net/10447/6614
Abstract
The feasibility of electrosynthesis of coenzyme Q10 (1) by electrooxidation of tetramethoxy precursor (2) has been investigated at carbon, Pt and BDD anodes in a divided cell. The process strongly depends on the applied potential, anode material and water content of the solvent. At carbon anodes in CH3CN/CH2Cl2 + 0.15 M Bu4NBF4 at proper operative conditions high faradic efficiency (>60%) and excellent selectivity (95-97%) of the target product were obtained.