Sequence type 101 (ST101) as the predominant carbapenem-non-susceptible Klebsiella pneumoniae clone in an acute general hospital in Italy.
- Authors: Mammina, C; Bonura, C; Aleo, A; Fasciana, T; Brunelli, T; Pesavento, G; Degl'Innocenti, R; Nastasi, A
- Publication year: 2012
- Type: Articolo in rivista (Articolo in rivista)
- OA Link: http://hdl.handle.net/10447/64906
Abstract
Klebsiella pneumoniae is one of the most common multidrug-resistant (MDR) Gram-negative organisms worldwide, responsible for high morbidity and mortality both in hospitals and alternative healthcare settings. Recently, increasing use of carbapenems has promoted the emergence and dissemination of carbapenem-non-susceptible MDR K. pneumoniae strains. All of the CNSKP strains isolated between January 2009 and December 2011 in the General Hospital of Prato (Prato, Italy) were studied. Our findings indicate that, unlike previously reported by other authors from different regions of Italy, K. pneumoniae producing KPC-2 and belonging to ST101 have been established in the area of Prato, Tuscany, Italy. This study confirms the previously reported involvement of multiple clones of K. pneumoniae in the spread of carbapenem resistance in Italy.