Isolation and characterization of Citrus limon L. derived nanovesicles: potential use as antineoplastic agent
- Autori: Raimondo, S.; Naselli, F.; Fontana, S.; Monteleone, F.; Lo Dico, A.; Saieva, L.; Zito, G.; Flugy Pape', AM.; Manno, M.; Di Bella, MA.; De Leo, G.; Alessandro, R.
- Anno di pubblicazione: 2015
- Tipologia: Proceedings
- Parole Chiave: nanovesicles, citrus limon
- OA Link: http://hdl.handle.net/10447/132213
Abstract
We isolated and characterized nanovesicles from edible Citrus limon with size and composition similar to mammalian-derived exosomes. Furthermore we show an in vitro and in vivo anti-proliferative and pro-apoptotic effect of these vesicles. This study opens to the possibility of using this natural plant-derived nanovesicles as antineoplastic agents.