Genetic heterogeneity and recombination in human type 2 astroviruses
- Authors: De Grazia, S; Medici, MC; Pinto, P; Moschidou, P; Tummolo, F; Calderaro, A; Bonura, F; Banyai, K; Giammanco, G; Martella, V
- Publication year: 2012
- Type: Articolo in rivista (Articolo in rivista)
- OA Link: http://hdl.handle.net/10447/77925
Abstract
Novel lineages of human astrovirus (HAstV) types 2, 2c, and 2d have been identified. Upon sequencing of the 3= end of the genome, the type 2c and 2d HAstVs were found to be open reading frame 1b (ORF1b)-ORF2 recombinant, with ORF1b being derived from type 3 and type 1 HAstVs, respectively. An ORF2 interlineage recombinant strain, 2c/2b, was also identified.