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SIMONA DE GRAZIA

Unusual assortment of segments in 2 rare human rotavirus genomes

  • Authors: De Grazia, S; Giammanco, G; Potgieter, CA; Matthijnssens, J; Bányai, K; Platia, MA; Colomba, C; Martella, V
  • Publication year: 2010
  • Type: Articolo in rivista (Articolo in rivista)
  • Key words: human rotavirus; G3P[9]; full genome sequencing; genotyping; interspecies transmission; reassortment
  • OA Link: http://hdl.handle.net/10447/49486

Abstract

Using full-length genome sequence analysis, we investigated 2 rare G3P[9] human rotavirus strains isolated from children with diarrhea. The genomes were recognized as assortments of genes closely related to rotaviruses originating from cats, ruminants, and humans. Results suggest multiple transmissions of genes from animal to human strains of rotaviruses.