Synthesis of the new oligopeptide pyrrole derivative isonetropsin and its one pyrrole unit analogue
- Authors: Montalbano, A; Parrino, B; Diana, P; Barraja, P; Carbone, A; Spanò, V; Cirrincione, G
- Publication year: 2013
- Type: Articolo in rivista (Articolo in rivista)
- Key words: Netropsin;DNA minor groove binders; Isonetropsin; Oligopeptide pyrrole
- OA Link: http://hdl.handle.net/10447/72064
Abstract
We have designed and synthesized isonetropsin and its one pyrrole unit analogue in which the amine and carbonyl groups have been switched in positions 2 and 4, respectively instead of 4 and 2 positions of the natural antibiotic netropsin.