A synthetic approach to new polycyclic ring system of biologial interest through domino reaction: indolo[2,3-e][1,2,3]triazolo[1,5-a]pyrimidine
- Authors: LAURIA A; PATELLA C; DIANA P; BARRAJA P; MONTALBANO A; CIRRINCIONE G; DATTOLO G; ALMERICO AM
- Publication year: 2006
- Type: Articolo in rivista (Articolo in rivista)
- OA Link: http://hdl.handle.net/10447/34517
Abstract
The title indolo-triazolo-pyrimidines were obtained from 3-azidoindoles and can be used as models for the design of DNA-interactive compounds. Hetero-domino reaction of azidoindoles/pyrroles and acetonitriles constitutes the synthetic entry to annelated 1,2,3-triazolo[1,5-a]pyrimidines.