Effects of apomorphine on orienting reaction in the rat
- Authors: Casarrubea,M;Sorbera,F;Crescimanno,G
- Publication year: 2009
- Type: Capitolo o Saggio (Capitolo o saggio)
- Key words: Dopamine; A9 and A10 neurons; Head turning; apomorphine; sensorimotor integration
- OA Link: http://hdl.handle.net/10447/50585
Abstract
Aim of the research was to study the possible relationship between rapid apomorphine-induced modifications of midbrain dopaminergic neuron activity and rapid modifications of a motor response triggered by sensory stimuli (sensory-motor integration. Following apomorphine administration, ANOVA test revealed significant decrease of head turning latency and duration. A change on dopamine release, leading to an inhibition or facilitation of dopamine-mediated responses to environmental stimuli, may be hypothesized.