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ANTONIO CASCIO

Clinical recrudescence of chronic untreated P. malariae infection after BNT162b2 CoVID-19 vaccine

  • Authors: Ciusa, G; Guida Marascia, F; Virruso, R; Angheben, A; Guaraldi, G; Cascio, A
  • Publication year: 2022
  • Type: Articolo in rivista
  • OA Link: http://hdl.handle.net/10447/574598

Abstract

We described a case of clinical reactivation of chronic P. malariae infection following CoVID-19 vaccination with BNT162b2 (Pifzer-Biontech CoVID-19 vaccine) in a 48-year old Italian man.The patient came to our attention for fever of unknown origin show a quartan pattern (every third day) associated to splenomegaly, the onset of the fever occurred one month after CoVID-19 vaccination with BNT162b2. P. malariae was diagnosed using CarestartTM malaria rapid test and Polymerase-Chain Reaction. Post-vaccine transient reduction of immune reactivity is described in literature, although the mechanism is unknown.(c) 2022 Published by Elsevier Ltd.CC_BY_NC_ND_4.0