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PAOLA BARRAJA

Synthesis of the new oligopeptide pyrrole derivative isonetropsin and its one pyrrole unit analogue

  • Autori: Montalbano, A; Parrino, B; Diana, P; Barraja, P; Carbone, A; Spanò, V; Cirrincione, G
  • Anno di pubblicazione: 2013
  • Tipologia: Articolo in rivista (Articolo in rivista)
  • Parole Chiave: Netropsin;DNA minor groove binders; Isonetropsin; Oligopeptide pyrrole
  • OA Link: http://hdl.handle.net/10447/72064

Abstract

We have designed and synthesized isonetropsin and its one pyrrole unit analogue in which the amine and carbonyl groups have been switched in positions 2 and 4, respectively instead of 4 and 2 positions of the natural antibiotic netropsin.