Synthesis of the New Ring System 2-Oxo-[1,4]oxazino[3,2-e]indole, Heteroanalogue of Angelicin
- Autori: BARRAJA, P; DIANA, P; MONTALBANO, A; MARTORANA, A; CARBONE, A; CIRRINCIONE, G
- Anno di pubblicazione: 2009
- Tipologia: Articolo in rivista (Articolo in rivista)
- Parole Chiave: 1,4-Oxazinoindoles; 1,4-Benzoxazines; Angelicin heteroanalogue; 4-Amino-5-hydroxy indoles
- OA Link: http://hdl.handle.net/10447/43884
Abstract
A series of 2-oxo-[1,4]oxazino[3,2-e ]indoles, heteroanalogues of Angelicin, have been synthesized by a multistep sequence consisting of the annelation of the oxazine ring on the indole moiety. The phototoxicity and the antiproliferative activity of the new derivatives were investigated.