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LUISA AGNELLO

Prostate health index (PHI) as a reliable biomarker for prostate cancer: a systematic review and meta-analysis

  • Authors: Agnello, Luisa; Vidali, Matteo; Giglio, Rosaria Vincenza; Gambino, Caterina Maria; Ciaccio, Anna Maria; Lo Sasso, Bruna; Ciaccio, Marcello
  • Publication year: 2022
  • Type: Articolo in rivista
  • OA Link: http://hdl.handle.net/10447/567471

Abstract

Prostate cancer (PCa) represents the second most common solid cancer in men worldwide. In the last decades, the prostate health index (PHI) emerged as a reliable biomarker for detecting PCa and differentiating between non-aggressive and aggressive forms. However, before introducing it in clinical practice, more evidence is required. Thus, we performed a systematic review and meta-analysis for assessing the diagnostic performance of PHI for PCa and for detecting clinically significant PCa (csPCa).