A Protein-Interaction Array Inside a Living Cell
- Autori: Gandor S; Reisewitz R; Venkatachalapathy M; Arrabito G; Reibner R; Schroeder H; Ruf K; Niemeyer C.M.; Bastiaens P.I.H; Dehmelt L
- Anno di pubblicazione: 2013
- Tipologia: Articolo in rivista (Articolo in rivista)
- OA Link: http://hdl.handle.net/10447/98143
Abstract
Protein-interaction arrays were generated in living cells by the interaction of bait-presenting artificial receptor constructs (bait-PARCs) with micrometer-scaled antibody surface patterns (see figure). This method was applied to simultaneously monitor the interaction kinetics of a prey protein with two distinct bait proteins in individual living cells.