Beta-glucans and cancer: The influence of inflammation and gut peptide
- Authors: Baldassano, Sara; Accardi, Giulia; Vasto, Sonya
- Publication year: 2017
- Type: Articolo in rivista (Articolo in rivista)
- Key words: Cancer; Ghrelin; GLP-1; GLP-2; Glucose; Inflammation; Insulin; PYY; β-Glucans; Animals; Ghrelin; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Humans; Inflammation; Neoplasms; Peptide YY; beta-Glucans; Functional Food; Pharmacology; Drug Discovery3003 Pharmaceutical Science; Organic Chemistry
- OA Link: http://hdl.handle.net/10447/305868
Abstract
Dietary β-glucans are soluble fibers with potentially health-promoting effects. Gut peptides are important signals in the regulation of energy and glucose homeostasis. This article reviews the effects of different enriched β-glucan food consumption on immune responses, inflammation, gut hormone and cancer. Gut hormones are influenced by enriched β-glucan food consumption and levels of such peptide as YY, ghrelin, glucagon-like peptide 1 and 2 in humans influence serum glucose concentration as well as innate and adaptive immunity. Cancer cell development is also regulated by obesity and glucose dishomeostasy that are influenced by β-glucan food consumption that in turn regulated gut hormones.