From cellular senescence to age-associated diseases: miRNAs as tools and targets for healthy ageing
- Authors: Accardi, G.; Caruso, C.; Grillari, J.
- Publication year: 2017
- Type: Contributo in atti di convegno pubblicato in volume
- OA Link: http://hdl.handle.net/10447/251189
Abstract
miRNAs are the most abundant RNA species to be found in cell-free blood, encapsulated within microvesicles or bound to proteins. miRNAs play essential roles in the regulation of various biological processes. Moreover, specific changes in miRNA transcription levels or miRNA secretory levels have been linked to the development and progression of certain age-related diseases. So, they might be an ideal target for modulating healthy ageing